EN DE
STOCK COMPARISON

Jiangsu Sihuan Bioengineering Co vs Vertex Pharmaceuticals: Fair Value & Quality

Both stocks run through our valuation models. Here is how Jiangsu Sihuan Bioengineering Co (000518) and Vertex Pharmaceuticals (VRTX) compare, as of Sep 24, 2026.

As of Sep 24, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the more attractively valued of the two: Jiangsu Sihuan Bioengineering Co trades at ¥3.78 versus a fair value of ¥1.67 (-56%), while Vertex Pharmaceuticals trades at $516 versus $566 (+10%).
Jiangsu Sihuan Bioengineering Co
000518.SHE · CNY · Health Care
-56%
upside to fair value
overvalued
Price¥3.78
Fair Value¥1.67
Quality70/100
Vertex Pharmaceuticals
VRTX · USD · Health Care
+10%
upside to fair value
fairly valued
Price$516
Fair Value$566
Quality79/100
Get comparisons like this free by email every month: the most undervalued quality stocks.

Head-to-head numbers

Green is the better side of a row, red the weaker one (for valuation multiples: lower = cheaper). Grey rows are for reference only and are not scored.

betterweakerfor reference, not scored

Jiangsu Sihuan Bioengineering CoVertex Pharmaceuticals
Valuation
n/aP/E (TTM)30.7×
1.74×P/S (TTM)10.90×
1.98×P/B7.14×
n/aEV/EBITDA25.8×
n/aPEG1.72×
−55.8%Fair value upside+9.7%
0.0%Dividend yieldn/a
Profitability
-15%Operating margin38%
n/aEBIT margin trend (5Y)0.86×
-10%Return on equity24%
-5%Return on assets12%
Growth
85%Revenue growth (YoY)8%
8.4%Avg. growth/yr (3Y)10.6%
-7.4%Avg. growth/yr (5Y)14.2%
n/aValue creation/yr+13.5%
Balance & size
n/aInterest coverage (EBIT/interest)357.9×
n/aDebt / equity0.03×
$663MMarket cap$133B
weakGrowth qualityhealthy

Vertex Pharmaceuticals leads: 2 to 6 metric wins.

n/a = not meaningfully computable, for example with negative equity.

Quality in detail

The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.

Jiangsu Sihuan Bioengineering Coof which business quality 72 · market factors 76 Vertex Pharmaceuticalsof which business quality 77 · market factors 73
ProfitabilityMargins and returns on capital today
19
72
Quality GrowthAre margins and returns improving?
70
65
CashflowEarnings quality: real cash, not paper profit
89
79
Fin. StrengthBalance sheet, leverage, solvency risk
90
92
InvestmentDisciplined investing over empire-building
100
58
Low VolatilityCalm price path (market factor)
66
85
MomentumPrice trend over the last 3–12 months (market factor)
80
65
52W MomentumDistance to the 52-week high (market factor)
82
75
Net IssuanceShare count: buybacks or dilution?
82
82

What the models say

How far the median fair value (base case) per model family sits from the current price, in percent. The amount in the currency of the trading venue is shown underneath.

above the price, more than 15% above close to the price, 85% to 115% of the price below the price, more than 15% below

Model familyJiangsu Sihuan Bioengineering CoPrice ¥3.78Vertex PharmaceuticalsPrice $516
DCF Models-59%below the price¥1.55-12%close to the price$453
Earnings-Basedn/a0%close to the price$516
Multiples-73%below the price¥1.03-46%below the price$278
Asset-Based-94%below the price¥0.22-90%below the price$49.27
Growth DCF-56%below the price¥1.68-32%below the price$349
Economic Profitn/a-53%below the price$245
Growth Earningsn/a+34%above the price$692
Minimum-94%below the price¥0.22-90%below the price$49.27
Maximum-56%below the price¥1.68+34%above the price$692
Median-66%below the price¥1.29-32%below the price$349
Geometric mean-77%below the price¥0.88-43%below the price$294

Minimum, maximum, median and geometric mean refer to the family values in this table. Geometric because deviations are ratios: half the price and twice the price average to 100%, not 125%.

Jiangsu Sihuan Bioengineering Co: 7 of 7 models see the stock below the current price.

Vertex Pharmaceuticals: 19 of 24 models see the stock below the current price.

Scenario ranges

From our cautious bear scenario to the optimistic bull scenario. The white tick is the current price (value above it), the green tick the fair value (value below it): if the price sits left of the fair value, there is room to rise.

Jiangsu Sihuan Bioengineering Co
Price ¥3.78
Fair Value ¥1.67
Bear ¥0.97Bull ¥2.67
Vertex Pharmaceuticals
Price $516
Fair Value $566
Bear $340Bull $1,226

Compare two other stocks

Tap a field and type again, ticker or company name.

Free, no sign-up

Ranked within their sector

Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.

Jiangsu Sihuan Bioengineering Co · Health Care

Quality score70 · Top 25%
Fair value upside-56% · below median

Vertex Pharmaceuticals · Health Care

Quality score79 · Top 25%
Fair value upside+10% · above median

Bottom line

As of Sep 24, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the more attractively valued of the two: Jiangsu Sihuan Bioengineering Co trades at ¥3.78 versus a fair value of ¥1.67 (-56%), while Vertex Pharmaceuticals trades at $516 versus $566 (+10%).

Vertex Pharmaceuticals has the higher quality score (79/100).

Open Vertex Pharmaceuticals live analysis →
Jiangsu Sihuan Bioengineering Co · Vertex Pharmaceuticals

More comparisons

Popular match-ups from the same sectors, all with fair value and quality score.

Related to Jiangsu Sihuan Bioengineering Co

Microsoft vs NvidiaApple vs MicrosoftNvidia vs Taiwan Semiconductor ManufacturingApple vs Taiwan Semiconductor Manufacturing

Related to Vertex Pharmaceuticals

Alphabet Inc Class C vs Meta PlatformsCisco Systems vs NvidiaMicrosoft vs Taiwan Semiconductor ManufacturingApple vs Cisco Systems
Free · Top-25 report

See the undervalued quality stocks every month

Just your email for the monthly Top-25 report of the most undervalued quality stocks, with fair value, quality and price target. Plus 14 days of Pro to try, no card.

Free. You confirm by email (double opt-in) and can unsubscribe anytime in one click. Not financial advice.

A model-based valuation snapshot from 26 models. Values change with price and fundamentals; the date shown above applies.