STOCK COMPARISON
Sino Biopharmaceutical vs Vertex Pharmaceuticals: Fair Value & Quality
Both stocks run through our valuation models. Here is how Sino Biopharmaceutical (1177) and Vertex Pharmaceuticals (VRTX) compare, as of Aug 8, 2026.
As of Aug 8, 2026, Fair Value Calculator sees Sino Biopharmaceutical as the less overvalued of the two: Sino Biopharmaceutical trades at HK$4.93 versus a fair value of HK$3.36 (-32%), while Vertex Pharmaceuticals trades at $484 versus $279 (-42%).
Sino Biopharmaceutical
1177.HK · HKD · Health Care
-32%
upside to fair value
overvalued
PriceHK$4.93
Fair ValueHK$3.36
Quality58/100
Vertex Pharmaceuticals
VRTX · USD · Health Care
-42%
upside to fair value
overvalued
Price$484
Fair Value$279
Quality74/100
Head-to-head numbers
Green value = the better side for that row (for valuation multiples: lower = cheaper).
Sino BiopharmaceuticalVertex Pharmaceuticals
Valuation
34.9×P/E (TTM)28.8×
2.92×P/S (TTM)10.06×
3.03×P/B6.59×
12.8×EV/EBITDA23.8×
2.92×PEG1.72×
1.8%Dividend yield—
HK$0.09Dividend per share—
Profitability
7%Net margin36%
20%Operating margin38%
13%Return on equity24%
6%Return on assets12%
Growth
10%Revenue growth (YoY)8%
6.9%Avg. growth/yr (3Y)10.6%
6.1%Avg. growth/yr (5Y)14.2%
Balance & size
0.25×Debt / equity0.03×
$12BMarket cap$123B
healthyGrowth qualityhealthy
Vertex Pharmaceuticals leads: 4 to 9 metric wins.
Dash = not meaningfully computable, for example with negative equity.
Quality in detail
The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.
Sino Biopharmaceuticalof which business quality 71 · market factors 31
Vertex Pharmaceuticalsof which business quality 77 · market factors 60
ProfitabilityMargins and returns on capital today
39
72
Quality GrowthAre margins and returns improving?
48
65
CashflowEarnings quality: real cash, not paper profit
93
79
Fin. StrengthBalance sheet, leverage, solvency risk
72
92
InvestmentDisciplined investing over empire-building
82
58
Low VolatilityCalm price path (market factor)
67
77
MomentumPrice trend over the last 3–12 months (market factor)
18
52
52W MomentumDistance to the 52-week high (market factor)
10
55
Net IssuanceBuybacks instead of dilution
97
82
What the models say
The median fair value (base case) per model family, each in the currency of its trading venue. Green = above the current price, red = below.
Sino Biopharmaceutical
DCF ModelsHK$7.62
Earnings-BasedHK$2.74
Dividend DiscountHK$1.49
MultiplesHK$3.56
Asset-BasedHK$1.16
Growth DCFHK$9.65
Economic ProfitHK$3.23
Growth EarningsHK$3.07
14 of 26 models see the stock below the current price.
Vertex Pharmaceuticals
DCF Models$429
Earnings-Based$516
Dividend Discount$7.07
Multiples$246
Asset-Based$49.27
Growth DCF$333
Economic Profit$254
Growth Earnings$672
19 of 26 models see the stock below the current price.
Scenario ranges
From our cautious bear case to the optimistic bull case. The white tick is the current price: left of fair value means room to run.
Sino Biopharmaceutical
Bear HK$2.52Fair Value HK$3.36Bull HK$4.19
HK$4.93 = current price (white tick)
Vertex Pharmaceuticals
Bear $210Fair Value $279Bull $900
$484 = current price (white tick)
Compare two other stocks
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Ranked within their sector
Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.
Sino Biopharmaceutical · Health Care
Quality score58 · above median
Fair value upside-32% · below median
Vertex Pharmaceuticals · Health Care
Quality score74 · Top 25%
Fair value upside-42% · below median
Bottom line
As of Aug 8, 2026, Fair Value Calculator sees Sino Biopharmaceutical as the less overvalued of the two: Sino Biopharmaceutical trades at HK$4.93 versus a fair value of HK$3.36 (-32%), while Vertex Pharmaceuticals trades at $484 versus $279 (-42%).
Vertex Pharmaceuticals has the higher quality score (74/100).
See the full analysis →
More comparisons
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A model-based valuation snapshot from 21 models. Values change with price and fundamentals; the date shown above applies.
