Genscript Biotech vs Vertex Pharmaceuticals: Fair Value & Quality
Both stocks run through our valuation models. Here is how Genscript Biotech (1548) and Vertex Pharmaceuticals (VRTX) compare, as of Aug 14, 2026.
As of Aug 14, 2026, Fair Value Calculator sees Genscript Biotech as the less overvalued of the two: Genscript Biotech trades at HK$24.88 versus a fair value of HK$15.14 (-39%), while Vertex Pharmaceuticals trades at $516 versus $279 (-46%).
Genscript Biotech
1548.HK · HKD · Health Care
-39%
upside to fair value
overvalued
PriceHK$24.88
Fair ValueHK$15.14
Quality55/100
Vertex Pharmaceuticals
VRTX · USD · Health Care
-46%
upside to fair value
overvalued
Price$516
Fair Value$279
Quality79/100
Head-to-head numbers
Green value = the better side for that row (for valuation multiples: lower = cheaper).
Genscript BiotechVertex Pharmaceuticals
Valuation
—P/E (TTM)28.8×
3.55×P/S (TTM)10.06×
0.86×P/B6.59×
10.2×EV/EBITDA23.8×
—PEG1.72×
Profitability
-56%Net margin36%
17%Operating margin38%
-13%Return on equity24%
3%Return on assets12%
Growth
43%Revenue growth (YoY)8%
15.3%Avg. growth/yr (3Y)10.6%
19.7%Avg. growth/yr (5Y)14.2%
Balance & size
—Debt / equity0.03×
$3BMarket cap$123B
mixedGrowth qualityhealthy
Genscript Biotech leads: 6 to 4 metric wins.
Dash = not meaningfully computable, for example with negative equity.
Quality in detail
The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.
Genscript Biotechof which business quality 59 · market factors 65Vertex Pharmaceuticalsof which business quality 77 · market factors 73
ProfitabilityMargins and returns on capital today
5
72
Quality GrowthAre margins and returns improving?
79
65
CashflowEarnings quality: real cash, not paper profit
InvestmentDisciplined investing over empire-building
21
58
Low VolatilityCalm price path (market factor)
39
86
MomentumPrice trend over the last 3–12 months (market factor)
67
60
52W MomentumDistance to the 52-week high (market factor)
90
80
Net IssuanceBuybacks instead of dilution
71
82
What the models say
The median fair value (base case) per model family, each in the currency of its trading venue. Green = above the current price, red = below.
Genscript Biotech
DCF ModelsHK$3.03
Earnings-BasedHK$1.06
MultiplesHK$2.07
Asset-BasedHK$1.21
Growth DCFHK$2.92
Economic ProfitHK$1.06
13 of 13 models see the stock below the current price.
Vertex Pharmaceuticals
DCF Models$453
Earnings-Based$516
Dividend Discount$7.07
Multiples$278
Asset-Based$49.27
Growth DCF$348
Economic Profit$254
Growth Earnings$692
21 of 26 models see the stock below the current price.
Scenario ranges
From our cautious bear case to the optimistic bull case. The white tick is the current price: left of fair value means room to run.
Genscript Biotech
Bear HK$11.30Fair Value HK$15.14Bull HK$19.07
HK$24.88 = current price (white tick)
Vertex Pharmaceuticals
Bear $210Fair Value $279Bull $900
$516 = current price (white tick)
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Ranked within their sector
Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.
Genscript Biotech · Health Care
Quality score55 · above median
Fair value upside-39% · below median
Vertex Pharmaceuticals · Health Care
Quality score79 · Top 25%
Fair value upside-46% · below median
Bottom line
As of Aug 14, 2026, Fair Value Calculator sees Genscript Biotech as the less overvalued of the two: Genscript Biotech trades at HK$24.88 versus a fair value of HK$15.14 (-39%), while Vertex Pharmaceuticals trades at $516 versus $279 (-46%).
Vertex Pharmaceuticals has the higher quality score (79/100).
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A model-based valuation snapshot from 21 models. Values change with price and fundamentals; the date shown above applies.
