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STOCK COMPARISON

Shanghai Serum Bio-Technology Co. Ltd. A vs Vertex Pharmaceuticals: Fair Value & Quality

Both stocks run through our valuation models. Here is how Shanghai Serum Bio-Technology Co. Ltd. A (688163) and Vertex Pharmaceuticals (VRTX) compare, as of Aug 10, 2026.

As of Aug 10, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the less overvalued of the two: Shanghai Serum Bio-Technology Co. Ltd. A trades at ¥32.68 versus a fair value of ¥7.95 (-76%), while Vertex Pharmaceuticals trades at $496 versus $279 (-44%).
Shanghai Serum Bio-Technology Co. Ltd. A
688163.SHG · CNY · Health Care
-76%
upside to fair value
overvalued
Price¥32.68
Fair Value¥7.95
Quality56/100
Vertex Pharmaceuticals
VRTX · USD · Health Care
-44%
upside to fair value
overvalued
Price$496
Fair Value$279
Quality79/100

Head-to-head numbers

Green value = the better side for that row (for valuation multiples: lower = cheaper).

Shanghai Serum Bio-Technology Co. Ltd. AVertex Pharmaceuticals
Valuation
97.9×P/E (TTM)28.8×
24.66×P/S (TTM)10.06×
4.38×P/B6.59×
71.2×EV/EBITDA23.8×
PEG1.72×
1.0%Dividend yield
¥0.38Dividend per share
Profitability
25%Net margin36%
-6%Operating margin38%
4%Return on equity24%
3%Return on assets12%
Growth
6%Revenue growth (YoY)8%
4.0%Avg. growth/yr (3Y)10.6%
1.1%Avg. growth/yr (5Y)14.2%
Balance & size
Debt / equity0.03×
$723MMarket cap$123B
weakGrowth qualityhealthy

Vertex Pharmaceuticals leads: 1 to 10 metric wins.

Dash = not meaningfully computable, for example with negative equity.

Quality in detail

The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.

Shanghai Serum Bio-Technology Co. Ltd. Aof which business quality 56 · market factors 70 Vertex Pharmaceuticalsof which business quality 77 · market factors 65
ProfitabilityMargins and returns on capital today
39
72
Quality GrowthAre margins and returns improving?
35
65
CashflowEarnings quality: real cash, not paper profit
41
79
Fin. StrengthBalance sheet, leverage, solvency risk
82
92
InvestmentDisciplined investing over empire-building
67
58
Low VolatilityCalm price path (market factor)
52
86
MomentumPrice trend over the last 3–12 months (market factor)
80
54
52W MomentumDistance to the 52-week high (market factor)
74
59
Net IssuanceBuybacks instead of dilution
82
82

What the models say

The median fair value (base case) per model family, each in the currency of its trading venue. Green = above the current price, red = below.

Shanghai Serum Bio-Technology Co. Ltd. A

DCF Models¥4.26
Earnings-Based¥4.99
Dividend Discount¥3.58
Multiples¥8.53
Asset-Based¥6.89
Growth DCF¥0.42
Economic Profit¥6.17
Growth Earnings¥7.95

23 of 23 models see the stock below the current price.

Vertex Pharmaceuticals

DCF Models$453
Earnings-Based$516
Dividend Discount$7.07
Multiples$278
Asset-Based$49.27
Growth DCF$348
Economic Profit$254
Growth Earnings$692

18 of 26 models see the stock below the current price.

Scenario ranges

From our cautious bear case to the optimistic bull case. The white tick is the current price: left of fair value means room to run.

Shanghai Serum Bio-Technology Co. Ltd. A
Bear ¥5.57Fair Value ¥7.95Bull ¥7.95
¥32.68 = current price (white tick)
Vertex Pharmaceuticals
Bear $210Fair Value $279Bull $900
$496 = current price (white tick)

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Ranked within their sector

Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.

Shanghai Serum Bio-Technology Co. Ltd. A · Health Care

Quality score56 · above median
Fair value upside-76% · bottom 25%

Vertex Pharmaceuticals · Health Care

Quality score79 · Top 25%
Fair value upside-44% · below median

Bottom line

As of Aug 10, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the less overvalued of the two: Shanghai Serum Bio-Technology Co. Ltd. A trades at ¥32.68 versus a fair value of ¥7.95 (-76%), while Vertex Pharmaceuticals trades at $496 versus $279 (-44%).

Vertex Pharmaceuticals has the higher quality score (79/100).

See the full analysis →

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A model-based valuation snapshot from 21 models. Values change with price and fundamentals; the date shown above applies.