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STOCK COMPARISON

Amgen vs Gilead Sciences: Fair Value & Quality

Both stocks run through our valuation models. Here is how Amgen (AMGN) and Gilead Sciences (GILD) compare, as of Oct 27, 2026.

As of Oct 27, 2026, Fair Value Calculator sees Gilead Sciences as the more attractively valued of the two: Amgen trades at $445 versus a fair value of $492 (+10.7%), while Gilead Sciences trades at $159 versus $199 (+25.3%).
Amgen
AMGN · USD · Health Care
+10.7%
upside to fair value
undervalued
Price$445
Fair Value$492
Quality64/100
Gilead Sciences
GILD · USD · Health Care
+25.3%
upside to fair value
undervalued
Price$159
Fair Value$199
Quality81/100
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Head-to-head numbers

Green is the better side of a row, red the weaker one (for valuation multiples: lower = cheaper). Grey rows are for reference only and are not scored.

betterweakerfor reference, not scored

AmgenGilead Sciences
Valuation
27.6×P/E (TTM)18.5×
36.5×P/E ex one-offs (FY2025)21.9×
18.2×Forward P/E (FY2027)16.0×
21.8×Median P/E at FY-end (10 FY, ex one-offs where documented)15.8×
6.35×P/S (TTM)6.48×
27.94× · book value is mostly goodwillP/B8.72× · book value is mostly goodwill
16.4×EV/EBITDA14.5×
2.45×PEG2.27×
+10.7%Fair value upside+25.3%
2.2%Dividend yield2.0%
$9.80Dividend per share$3.22
Profitability
35.6%Operating margin33.7%
0.81×EBIT margin trend (5Y)2.41×
91.5%Return on equity-20.7%
8.5%Return on assets14.4%
Growth
9.5%Revenue growth (YoY)10.2%
11.8%Avg. growth/yr (3Y)2.6%
7.6%Avg. growth/yr (5Y)3.6%
+2.0%Value creation/yr+10.4%
Balance & size
3.9×Interest coverage (EBIT/interest)11.4×
5.78×Debt / equity0.98×
$242BMarket cap$197B
healthyGrowth qualityhealthy
The P/E excluding one-off items is scored: for at least one of the two companies, special items (write-downs, restructuring, litigation) move the reported P/E by 15 % or more. The trailing P/E is shown for reference.
Amgen, median P/E at fiscal year-end, 10 fiscal years (2016 to 2025), reported earnings, FY2017, FY2024, FY2025 ex one-offs: 21.8. Gilead Sciences, median P/E at fiscal year-end, 10 fiscal years (2016 to 2025), reported earnings, 8 of the years ex one-offs: 15.8.
Forward P/E: price divided by the analyst consensus for the first fiscal year that has not started yet. The current year carries special items from quarters already reported.

Gilead Sciences leads: 5 to 9 metric wins.

n/a = not meaningfully computable, for example with negative equity.

Quality in detail

The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.

Amgen Gilead Sciences
ProfitabilityHow much profit the company makes from its sales and capital
64
77
Quality GrowthAre margins and returns getting better?
79
67
CashflowDo the profits arrive as real cash?
78
86
Financial strengthDebt, balance sheet and risk of trouble
23
64
InvestmentDoes it invest with discipline instead of growing at any price?
42
97
Low VolatilityHow calm the share price moves, does not count
84
87
MomentumPrice trend of the last 3 to 12 months, does not count
78
70
Near the 52-week highDistance to the 52-week high, does not count
97
86
New sharesBuys back shares or issues new ones?
78
89

What the models say

How far the median fair value (base case) per model family sits from the current price, in percent. The amount in the currency of the trading venue is shown underneath.

above the price, more than 15% above close to the price, 85% to 115% of the price below the price, more than 15% below

Model familyAmgenPrice $445Gilead SciencesPrice $159
DCF Models−15.7%below the price$375+54.5%above the price$245
Earnings-Based−65.9%below the price$152−8.8%close to the price$145
Dividend Discount−52.2%below the price$213−58.1%below the price$66.51
Multiples−43.4%below the price$252−7.6%close to the price$147
Growth DCF−23.0%below the price$342+32.0%above the price$210
Economic Profit−64.2%below the price$159−28.5%below the price$114
Growth Earnings−41.4%below the price$261+25.3%above the price$199
Matching families7 of 7
Minimum−65.9%below the price$152−58.1%below the price$66.51
Maximum−15.7%below the price$375+54.5%above the price$245
Median−43.4%below the price$252−7.6%close to the price$147
Geometric mean−46.5%below the price$238−6.1%close to the price$149
Ahead family by family1 of 76 of 7

Minimum, maximum, median and geometric mean only use the families both stocks have (matching families: 7 of 7), so a family without a value on one side does not distort the comparison. Ahead in a family is the stock whose fair value there sits higher relative to its price. Geometric because deviations are ratios: half the price and twice the price average to 100%, not 125%.

Family by family: Gilead Sciences is ahead in 6 of 7 shared families, Amgen in 1.

Amgen: 21 of 24 models see the stock below the current price.

Gilead Sciences: 14 of 24 models see the stock below the current price.

Scenario ranges

From our cautious bear scenario to the optimistic bull scenario. The white tick is the current price (value above it), the green tick the fair value (value below it): if the price sits left of the fair value, there is room to rise.

Amgen
Price $445
Fair Value $492
Bear $337Bull $640
Gilead Sciences
Price $159
Fair Value $199
Bear $118Bull $258

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Ranked within their sector

Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.

Amgen · Health Care

Quality score64 · above median
Fair value upside+10.7% · above median

Gilead Sciences · Health Care

Quality score81 · Top 25%
Fair value upside+25.3% · Top 25%

Bottom line

As of Oct 27, 2026, Fair Value Calculator sees Gilead Sciences as the more attractively valued of the two: Amgen trades at $445 versus a fair value of $492 (+10.7%), while Gilead Sciences trades at $159 versus $199 (+25.3%).

Gilead Sciences has the higher quality score (81/100).

Open Gilead Sciences live analysis →

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A model-based valuation snapshot from 26 models. Values change with price and fundamentals; the date shown above applies.