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STOCK COMPARISON

Anavex Life Sciences vs Vertex Pharmaceuticals: Fair Value & Quality

Both stocks run through our valuation models. Here is how Anavex Life Sciences (AVXL) and Vertex Pharmaceuticals (VRTX) compare, as of Sep 25, 2026.

As of Sep 25, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the more attractively valued of the two: Anavex Life Sciences trades at $2.34 versus a fair value of $1.02 (-56%), while Vertex Pharmaceuticals trades at $522 versus $575 (+10%).
Anavex Life Sciences
AVXL · USD · Health Care
-56%
upside to fair value
overvalued
Price$2.34
Fair Value$1.02
Quality51/100
Vertex Pharmaceuticals
VRTX · USD · Health Care
+10%
upside to fair value
undervalued
Price$522
Fair Value$575
Quality80/100
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Head-to-head numbers

Green is the better side of a row, red the weaker one (for valuation multiples: lower = cheaper). Grey rows are for reference only and are not scored.

betterweakerfor reference, not scored

Anavex Life SciencesVertex Pharmaceuticals
Valuation
n/aP/E (TTM)30.4×
n/aP/E ex one-offs (FY2025)31.0×
n/aP/S (TTM)10.61×
2.54×P/B7.16×
n/aEV/EBITDA25.3×
n/aPEG1.89×
−56.4%Fair value upside+10.0%
Profitability
0%Operating margin38%
n/aEBIT margin trend (5Y)0.86×
-13%Return on equity24%
-10%Return on assets12%
Growth
0%Revenue growth (YoY)13%
n/aAvg. growth/yr (3Y)10.6%
n/aAvg. growth/yr (5Y)14.2%
n/aValue creation/yr+13.5%
Balance & size
n/aInterest coverage (EBIT/interest)357.9×
n/aDebt / equity0.03×
$241MMarket cap$134B
n/aGrowth qualityhealthy
The P/E excluding one-off items is only shown where the special items are documented in the accounts (our own raw data or SEC filings). If one side lacks it, the reported P/E stays scored.

Vertex Pharmaceuticals leads: 1 to 3 metric wins.

n/a = not meaningfully computable, for example with negative equity.

Quality in detail

The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.

Anavex Life Sciencesof which business quality 50 · market factors 17 Vertex Pharmaceuticalsof which business quality 78 · market factors 75
ProfitabilityMargins and returns on capital today
0
72
Quality GrowthAre margins and returns improving?
25
65
CashflowEarnings quality: real cash, not paper profit
61
79
Fin. StrengthBalance sheet, leverage, solvency risk
100
92
InvestmentDisciplined investing over empire-building
100
58
Low VolatilityCalm price path (market factor)
25
85
MomentumPrice trend over the last 3–12 months (market factor)
21
66
52W MomentumDistance to the 52-week high (market factor)
0
78
Net IssuanceShare count: buybacks or dilution?
21
89

What the models say

How far the median fair value (base case) per model family sits from the current price, in percent. The amount in the currency of the trading venue is shown underneath.

above the price, more than 15% above close to the price, 85% to 115% of the price below the price, more than 15% below

Model familyAnavex Life SciencesPrice $2.34Vertex PharmaceuticalsPrice $522
DCF Modelsn/a-13%close to the price$454
Earnings-Basedn/a-1%close to the price$517
Multiplesn/a-47%below the price$279
Asset-Based-71%below the price$0.69-91%below the price$49.34
Growth DCFn/a-33%below the price$349
Economic Profitn/a-53%below the price$245
Growth Earningsn/a+33%above the price$693
Minimum-71%below the price$0.69-91%below the price$49.34
Maximum-71%below the price$0.69+33%above the price$693
Median-71%below the price$0.69-33%below the price$349
Geometric mean-71%below the price$0.69-44%below the price$294

Minimum, maximum, median and geometric mean refer to the family values in this table. Geometric because deviations are ratios: half the price and twice the price average to 100%, not 125%.

Anavex Life Sciences: 1 of 1 models see the stock below the current price.

Vertex Pharmaceuticals: 19 of 24 models see the stock below the current price.

Scenario ranges

From our cautious bear scenario to the optimistic bull scenario. The white tick is the current price (value above it), the green tick the fair value (value below it): if the price sits left of the fair value, there is room to rise.

Anavex Life Sciences
Price $2.34
Fair Value $1.02
Bear $0.68Bull $1.28
Vertex Pharmaceuticals
Price $522
Fair Value $575
Bear $345Bull $1,244

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Ranked within their sector

Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.

Anavex Life Sciences · Health Care

Quality score51 · below median
Fair value upside-56% · below median

Vertex Pharmaceuticals · Health Care

Quality score80 · Top 25%
Fair value upside+10% · above median

Bottom line

As of Sep 25, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the more attractively valued of the two: Anavex Life Sciences trades at $2.34 versus a fair value of $1.02 (-56%), while Vertex Pharmaceuticals trades at $522 versus $575 (+10%).

Vertex Pharmaceuticals has the higher quality score (80/100).

Open Vertex Pharmaceuticals live analysis →

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A model-based valuation snapshot from 26 models. Values change with price and fundamentals; the date shown above applies.