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STOCK COMPARISON

Coltene Holding vs Intuitive Surgical: Fair Value & Quality

Both stocks run through our valuation models. Here is how Coltene Holding (CLTN) and Intuitive Surgical (ISRG) compare, as of Sep 29, 2026.

As of Sep 29, 2026, Fair Value Calculator sees Coltene Holding as the less overvalued of the two: Coltene Holding trades at CHF 45.60 versus a fair value of CHF 38.40 (−15.8%), while Intuitive Surgical trades at $415 versus $349 (−15.9%).
Coltene Holding
CLTN.SW · CHF · Health Care
−15.8%
upside to fair value
overvalued
PriceCHF 45.60
Fair ValueCHF 38.40
Quality62/100
Intuitive Surgical
ISRG · USD · Health Care
−15.9%
upside to fair value
overvalued
Price$415
Fair Value$349
Quality74/100
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Head-to-head numbers

Green is the better side of a row, red the weaker one (for valuation multiples: lower = cheaper). Grey rows are for reference only and are not scored.

betterweakerfor reference, not scored

Coltene HoldingIntuitive Surgical
Valuation
18.2×P/E (TTM)47.4×
n/aForward P/E (FY2027)34.3×
n/aMedian P/E at FY-end (5 FY, ex one-offs where documented)71.9×
1.32×P/S (TTM)13.48×
3.14×P/B8.34×
11.1×EV/EBITDA34.8×
4.34×PEG1.87×
−15.8%Fair value upside−15.9%
0.6%Dividend yieldn/a
CHF 0.28Dividend per sharen/a
Profitability
11.1%Operating margin33.6%
0.90×EBIT margin trend (5Y)1.22×
14.3%Return on equity17.4%
7.1%Return on assets10.5%
Growth
-0.5%Revenue growth (YoY)18.5%
-3.5%Avg. growth/yr (3Y)17.4%
-0.7%Avg. growth/yr (5Y)18.2%
−5.1%Value creation/yr+21.8%
Balance & size
40.1×Interest coverage (EBIT/interest)99.2×
$380MMarket cap$149B
weakGrowth qualityhealthy
Intuitive Surgical, median P/E at fiscal year-end, 5 fiscal years (2021 to 2025), reported earnings, FY2022 ex one-offs: 71.9.
Forward P/E: price divided by the analyst consensus for the first fiscal year that has not started yet. The current year carries special items from quarters already reported.

Intuitive Surgical leads: 5 to 9 metric wins.

n/a = not meaningfully computable, for example with negative equity.

Quality in detail

The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.

Coltene Holdingof which business quality 61 · market factors 43 Intuitive Surgicalof which business quality 72 · market factors 33
ProfitabilityMargins and returns on capital today
61
66
Quality GrowthAre margins and returns improving?
17
66
CashflowEarnings quality: real cash, not paper profit
35
79
Fin. StrengthBalance sheet, leverage, solvency risk
79
82
InvestmentDisciplined investing over empire-building
100
37
Low VolatilityCalm price path (market factor)
68
39
MomentumPrice trend over the last 3–12 months (market factor)
37
31
52W MomentumDistance to the 52-week high (market factor)
26
30
Net IssuanceShare count: buybacks or dilution?
82
87

What the models say

How far the median fair value (base case) per model family sits from the current price, in percent. The amount in the currency of the trading venue is shown underneath.

above the price, more than 15% above close to the price, 85% to 115% of the price below the price, more than 15% below

Model familyColtene HoldingPrice CHF 45.60Intuitive SurgicalPrice $415
DCF Models−19.1%below the priceCHF 36.87−47.7%below the price$217
Earnings-Based−35.2%below the priceCHF 29.54−61.8%below the price$158
Dividend Discount−46.5%below the priceCHF 24.40−99.9%below the price$0.40
Multiples+13.0%close to the priceCHF 51.53−65.7%below the price$142
Asset-Based−75.3%below the priceCHF 11.27−92.0%below the price$33.33
Growth DCF−35.4%below the priceCHF 29.48−55.7%below the price$184
Economic Profit−46.6%below the priceCHF 24.37−75.0%below the price$104
Growth Earnings−8.9%close to the priceCHF 41.55−46.6%below the price$222
Minimum−75.3%below the priceCHF 11.27−99.9%below the price$0.40
Maximum+13.0%close to the priceCHF 51.53−46.6%below the price$222
Median−35.3%below the priceCHF 29.51−63.8%below the price$150
Geometric mean−37.1%below the priceCHF 28.70−84.6%below the price$63.73

Minimum, maximum, median and geometric mean refer to the family values in this table. Geometric because deviations are ratios: half the price and twice the price average to 100%, not 125%.

Coltene Holding: 19 of 24 models see the stock below the current price.

Intuitive Surgical: 26 of 26 models see the stock below the current price.

Scenario ranges

From our cautious bear scenario to the optimistic bull scenario. The white tick is the current price (value above it), the green tick the fair value (value below it): if the price sits left of the fair value, there is room to rise.

Coltene Holding
Price CHF 45.60
Fair Value CHF 38.40
Bear CHF 26.15Bull CHF 53.90
Intuitive Surgical
Price $415
Fair Value $349
Bear $214Bull $576

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Ranked within their sector

Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.

Coltene Holding · Health Care

Quality score62 · Top 25%
Fair value upside−15.8% · above median

Intuitive Surgical · Health Care

Quality score74 · Top 25%
Fair value upside−15.9% · above median

Bottom line

As of Sep 29, 2026, Fair Value Calculator sees Coltene Holding as the less overvalued of the two: Coltene Holding trades at CHF 45.60 versus a fair value of CHF 38.40 (−15.8%), while Intuitive Surgical trades at $415 versus $349 (−15.9%).

Intuitive Surgical has the higher quality score (74/100).

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A model-based valuation snapshot from 26 models. Values change with price and fundamentals; the date shown above applies.