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STOCK COMPARISON

Vertex Pharmaceuticals vs Regeneron Pharmaceuticals: Fair Value & Quality

Both stocks run through our valuation models. Here is how Vertex Pharmaceuticals (VRTX) and Regeneron Pharmaceuticals (REGN) compare, as of Aug 8, 2026.

As of Aug 8, 2026, Fair Value Calculator sees Regeneron Pharmaceuticals as the less overvalued of the two: Vertex Pharmaceuticals trades at $484 versus a fair value of $279 (-42%), while Regeneron Pharmaceuticals trades at $772 versus $594 (-23%).
Vertex Pharmaceuticals
VRTX · USD · Health Care
-42%
upside to fair value
overvalued
Price$484
Fair Value$279
Quality74/100
Regeneron Pharmaceuticals
REGN · USD · Health Care
-23%
upside to fair value
overvalued
Price$772
Fair Value$594
Quality72/100

Head-to-head numbers

Green value = the better side for that row (for valuation multiples: lower = cheaper).

Vertex PharmaceuticalsRegeneron Pharmaceuticals
Valuation
28.8×P/E (TTM)16.2×
10.06×P/S (TTM)4.61×
6.59×P/B2.20×
23.8×EV/EBITDA15.4×
1.72×PEG1.15×
Dividend yield0.5%
Dividend per share$3.58
Profitability
36%Net margin30%
38%Operating margin21%
24%Return on equity15%
12%Return on assets6%
Growth
8%Revenue growth (YoY)19%
10.6%Avg. growth/yr (3Y)5.6%
14.2%Avg. growth/yr (5Y)11.0%
Balance & size
0.03×Debt / equity0.06×
$123BMarket cap$69B
healthyGrowth qualityhealthy

Vertex Pharmaceuticals leads: 7 to 6 metric wins.

Dash = not meaningfully computable, for example with negative equity.

Quality in detail

The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.

Vertex Pharmaceuticalsof which business quality 77 · market factors 60 Regeneron Pharmaceuticalsof which business quality 72 · market factors 68
ProfitabilityMargins and returns on capital today
72
60
Quality GrowthAre margins and returns improving?
65
45
CashflowEarnings quality: real cash, not paper profit
79
80
Fin. StrengthBalance sheet, leverage, solvency risk
92
84
InvestmentDisciplined investing over empire-building
58
54
Low VolatilityCalm price path (market factor)
77
79
MomentumPrice trend over the last 3–12 months (market factor)
52
53
52W MomentumDistance to the 52-week high (market factor)
55
80
Net IssuanceBuybacks instead of dilution
82
99

What the models say

The median fair value (base case) per model family, each in the currency of its trading venue. Green = above the current price, red = below.

Vertex Pharmaceuticals

DCF Models$429
Earnings-Based$516
Dividend Discount$7.07
Multiples$246
Asset-Based$49.27
Growth DCF$333
Economic Profit$254
Growth Earnings$672

19 of 26 models see the stock below the current price.

Regeneron Pharmaceuticals

DCF Models$1,093
Earnings-Based$1,116
Dividend Discount$63.24
Multiples$584
Asset-Based$203
Growth DCF$946
Economic Profit$371
Growth Earnings$1,399

13 of 26 models see the stock below the current price.

Scenario ranges

From our cautious bear case to the optimistic bull case. The white tick is the current price: left of fair value means room to run.

Vertex Pharmaceuticals
Bear $210Fair Value $279Bull $900
$484 = current price (white tick)
Regeneron Pharmaceuticals
Bear $447Fair Value $594Bull $1,731
$772 = current price (white tick)

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Ranked within their sector

Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.

Vertex Pharmaceuticals · Health Care

Quality score74 · Top 25%
Fair value upside-42% · below median

Regeneron Pharmaceuticals · Health Care

Quality score72 · Top 25%
Fair value upside-23% · above median

Bottom line

As of Aug 8, 2026, Fair Value Calculator sees Regeneron Pharmaceuticals as the less overvalued of the two: Vertex Pharmaceuticals trades at $484 versus a fair value of $279 (-42%), while Regeneron Pharmaceuticals trades at $772 versus $594 (-23%).

Vertex Pharmaceuticals has the higher quality score (74/100).

See the full analysis →

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A model-based valuation snapshot from 21 models. Values change with price and fundamentals; the date shown above applies.