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STOCK COMPARISON

Jacobio Pharmaceuticals Group Co Lt vs Vertex Pharmaceuticals: Fair Value & Quality

Both stocks run through our valuation models. Here is how Jacobio Pharmaceuticals Group Co Lt (1167) and Vertex Pharmaceuticals (VRTX) compare, as of Aug 16, 2026.

As of Aug 16, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the less overvalued of the two: Jacobio Pharmaceuticals Group Co Lt trades at HK$5.28 versus a fair value of HK$0.68 (-87%), while Vertex Pharmaceuticals trades at $506 versus $279 (-45%).
Jacobio Pharmaceuticals Group Co Lt
1167.HK · HKD · Health Care
-87%
upside to fair value
overvalued
PriceHK$5.28
Fair ValueHK$0.68
Quality42/100
Vertex Pharmaceuticals
VRTX · USD · Health Care
-45%
upside to fair value
overvalued
Price$506
Fair Value$279
Quality79/100

Head-to-head numbers

Green value = the better side for that row (for valuation multiples: lower = cheaper).

Jacobio Pharmaceuticals Group Co LtVertex Pharmaceuticals
Valuation
P/E (TTM)28.8×
8.91×P/S (TTM)10.06×
0.62×P/B6.59×
EV/EBITDA23.8×
PEG1.72×
0.5%Dividend yield0.1%
Profitability
Net margin36%
Operating margin38%
-17%Return on equity24%
-8%Return on assets12%
Growth
-95%Revenue growth (YoY)8%
-18.3%Avg. growth/yr (3Y)10.6%
-36.0%Avg. growth/yr (5Y)14.2%
Balance & size
0.12×Debt / equity0.03×
$477MMarket cap$123B
weakGrowth qualityhealthy

Vertex Pharmaceuticals leads: 3 to 6 metric wins.

Dash = not meaningfully computable, for example with negative equity.

Quality in detail

The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.

Jacobio Pharmaceuticals Group Co Ltof which business quality 42 · market factors 27 Vertex Pharmaceuticalsof which business quality 77 · market factors 70
ProfitabilityMargins and returns on capital today
1
72
Quality GrowthAre margins and returns improving?
14
65
CashflowEarnings quality: real cash, not paper profit
18
79
Fin. StrengthBalance sheet, leverage, solvency risk
71
92
InvestmentDisciplined investing over empire-building
100
58
Low VolatilityCalm price path (market factor)
50
86
MomentumPrice trend over the last 3–12 months (market factor)
24
58
52W MomentumDistance to the 52-week high (market factor)
8
74
Net IssuanceBuybacks instead of dilution
77
82

What the models say

The median fair value (base case) per model family, each in the currency of its trading venue. Green = above the current price, red = below.

Jacobio Pharmaceuticals Group Co Lt

Dividend DiscountHK$0.23
Asset-BasedHK$0.66

3 of 3 models see the stock below the current price.

Vertex Pharmaceuticals

DCF Models$453
Earnings-Based$516
Dividend Discount$7.07
Multiples$278
Asset-Based$49.27
Growth DCF$348
Economic Profit$254
Growth Earnings$692

19 of 26 models see the stock below the current price.

Scenario ranges

From our cautious bear case to the optimistic bull case. The white tick is the current price: left of fair value means room to run.

Jacobio Pharmaceuticals Group Co Lt
Bear HK$0.45Fair Value HK$0.68Bull HK$0.85
HK$5.28 = current price (white tick)
Vertex Pharmaceuticals
Bear $210Fair Value $279Bull $900
$506 = current price (white tick)

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Ranked within their sector

Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.

Jacobio Pharmaceuticals Group Co Lt · Health Care

Quality score42 · below median
Fair value upside-87% · bottom 25%

Vertex Pharmaceuticals · Health Care

Quality score79 · Top 25%
Fair value upside-45% · below median

Bottom line

As of Aug 16, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the less overvalued of the two: Jacobio Pharmaceuticals Group Co Lt trades at HK$5.28 versus a fair value of HK$0.68 (-87%), while Vertex Pharmaceuticals trades at $506 versus $279 (-45%).

Vertex Pharmaceuticals has the higher quality score (79/100).

See the full analysis →

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A model-based valuation snapshot from 21 models. Values change with price and fundamentals; the date shown above applies.