Canf vs Vertex Pharmaceuticals: Fair Value & Quality
Both stocks run through our valuation models. Here is how Canf (CANF) and Vertex Pharmaceuticals (VRTX) compare, as of Aug 27, 2026.
As of Aug 27, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the less overvalued of the two: Canf trades at ILS 5.17 versus a fair value of ILS 2.60 (-50%), while Vertex Pharmaceuticals trades at $547 versus $279 (-49%).
Canf
CANF.TA · ILA · Health Care
-50%
upside to fair value
overvalued
PriceILS 5.17
Fair ValueILS 2.60
Quality41/100
Vertex Pharmaceuticals
VRTX · USD · Health Care
-49%
upside to fair value
overvalued
Price$547
Fair Value$279
Quality79/100
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Head-to-head numbers
Green value = the better side for that row (for valuation multiples: lower = cheaper).
CanfVertex Pharmaceuticals
Valuation
—P/E (TTM)28.8×
18.74×P/S (TTM)10.06×
1.36×P/B6.59×
—EV/EBITDA23.8×
—PEG1.72×
—Dividend yield0.1%
Profitability
0%Net margin36%
—Operating margin38%
-178%Return on equity24%
-67%Return on assets12%
Growth
-43%Revenue growth (YoY)8%
-18.5%Avg. growth/yr (3Y)10.6%
-10.5%Avg. growth/yr (5Y)14.2%
Balance & size
—Debt / equity0.03×
$8MMarket cap$123B
weakGrowth qualityhealthy
Vertex Pharmaceuticals leads: 1 to 7 metric wins.
Dash = not meaningfully computable, for example with negative equity.
Quality in detail
The quality score, broken down into the same factor families as on the stock page, 0 to 100 per family.
Canfof which business quality 41 · market factors 25Vertex Pharmaceuticalsof which business quality 77 · market factors 78
ProfitabilityMargins and returns on capital today
2
72
Quality GrowthAre margins and returns improving?
7
65
CashflowEarnings quality: real cash, not paper profit
InvestmentDisciplined investing over empire-building
86
58
Low VolatilityCalm price path (market factor)
50
85
MomentumPrice trend over the last 3–12 months (market factor)
22
67
52W MomentumDistance to the 52-week high (market factor)
2
89
Net IssuanceBuybacks instead of dilution
100
82
What the models say
The median fair value (base case) per model family, each in the currency of its trading venue. Green = above the current price, red = below.
Canf
Asset-BasedILS 0.87
1 of 1 models see the stock below the current price.
Vertex Pharmaceuticals
DCF Models$453
Earnings-Based$516
Dividend Discount$7.07
Multiples$278
Asset-Based$49.27
Growth DCF$348
Economic Profit$254
Growth Earnings$692
22 of 26 models see the stock below the current price.
Scenario ranges
From our cautious bear case to the optimistic bull case. The white tick is the current price: left of fair value means room to run.
Canf
Bear ILS 1.94Fair Value ILS 2.60Bull ILS 3.88
ILS 5.17 = current price (white tick)
Vertex Pharmaceuticals
Bear $210Fair Value $279Bull $900
$547 = current price (white tick)
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Ranked within their sector
Where each stock sits within its sector peer group. Band = middle 50% of peers, tick = median, dot = this stock.
Canf · Health Care
Quality score41 · below median
Fair value upside-50% · below median
Vertex Pharmaceuticals · Health Care
Quality score79 · Top 25%
Fair value upside-49% · below median
Bottom line
As of Aug 27, 2026, Fair Value Calculator sees Vertex Pharmaceuticals as the less overvalued of the two: Canf trades at ILS 5.17 versus a fair value of ILS 2.60 (-50%), while Vertex Pharmaceuticals trades at $547 versus $279 (-49%).
Vertex Pharmaceuticals has the higher quality score (79/100).
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A model-based valuation snapshot from 26 models. Values change with price and fundamentals; the date shown above applies.
