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Can-Fite BioPharma Ltd (CANF) Fair Value & Analysis

Healthcare · Il · Market cap 22.5M ILA

CF Can-Fite BioPharma Ltd CANF · TA
Price5.17 ILA
Fair Value2.60 ILA
Upside-49.7%
Quality40/100
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Risks

!Trades 99% ABOVE our fair value of 2.60 ILA
!Weak Growth (revenue 5y −10.5 %/yr)
!Thin margins · 0.0% net margin
!negative free cash flow
Weak Growth (revenue 5y −10.5 %/yr)
Thin margins · 0.0% net margin
negative free cash flow
Trails peers (2/8)
Narrow moat 3/100
Evidence: Low Range 1.94 ILA – 3.88 ILA Share as image

Fair value as of: Aug 26, 2026

From 1 valuation models · updated yesterday

Share price +4.5% over the past month.

Below-average quality, and trading another 99% above our fair value.

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69 individual criteria per stock, every one traceable See the method →

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What matters now

  • The price sits above even our optimistic bull case (3.88 ILA). The favourable scenario is already priced in.
  • Weak quality (40/100) and above fair value at the same time, the margin of safety is missing on both counts.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.
  • A fairly wide model range (1.94 ILA to 3.88 ILA) leaves room in how you read the outcome.
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Price vs Fair Value (5 years)

780.00 ILA 3.97 ILA Fair Value 2.60 ILA Apr 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Aug 26, 2026.

How to read this chart

60‑month range 3.97 ILA – 780.00 ILA · fair‑value band 1.94 ILA – 3.88 ILA · the 5.17 ILA price screens above the 2.60 ILA fair value. Dashed = 300-day average. As of Aug 26, 2026.

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Analysis

Can-Fite BioPharma Ltd (CANF) currently trades at 5.17 ILA, while our model-based Fair Value estimate is 2.60 ILA, implying the stock looks roughly 49.7% overvalued today. The Quality Score stands at 40/100 (below-average quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: low).

Trailing-twelve-month revenue stands at 405K ILA. Revenue declined 43.3% year over year. The balance sheet holds a net cash position of 5.5M ILA. Fundamentals as of Aug 26, 2026

Our scenario range runs from 1.94 ILA (bear case) to 3.88 ILA (bull case); at 5.17 ILA, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. For context, the median of 10 Healthcare peers we cover trades at -60% fair-value upside, at -50%, CANF screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
NCAV (Graham) 0.6500 ILA 0.8700 ILA 1.31 ILA 50
All 1 models by family
Asset-Based
NCAV (Graham) 0.6500 ILA 0.8700 ILA 1.31 ILA 50

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Key figures & financial health

P/S ratio 48.3 TTM
Return on equity -178% TTM
Return on assets -66.8% TTM
Operating margin -2,489% TTM
EPS (TTM) -15.54 ILA
Revenue (TTM) 405K ILA TTM
More key figures
Growth
Revenue growth (YoY) -43.3% 3y avg -18.5%
Balance sheet & cash flow
Free cash flow −9.7M ILA FY2025
Net cash 5.5M ILA FY2025

Figures from reported company fundamentals · as of Aug 26, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 40/100

Of which business quality 41 · Market factors (momentum, volatility) 25

Profitability 2
Margins and returns on capital today
Quality Growth 7
Are margins and returns improving?
Cashflow 9
Earnings quality: real cash, not paper profit
Fin. Strength 72
Balance sheet, leverage, solvency risk
Investment 86
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 22
Price trend over the last 3–12 months (market factor)
52W Momentum 2
Distance to the 52-week high (market factor)
Net Issuance 100
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

All values are scores from 0 to 100 (100 = best against fixed, research-based bands), not percentages. The three market factors (momentum, 52-week proximity, low volatility) are displayed but carry zero weight in the headline number: market sentiment is not a business property.

About the company

Can-Fite BioPharma Ltd., a clinical-stage biopharmaceutical company, develops orally bioavailable small molecule therapeutic products for the treatment of cancer, liver inflammatory diseases, and erectile dysfunction in Israel. The company's lead drug candidate Piclidenoson, which has been completed Phase III clinical trial for the treatment of psoriasis.

Full company description

Can-Fite BioPharma Ltd., a clinical-stage biopharmaceutical company, develops orally bioavailable small molecule therapeutic products for the treatment of cancer, liver inflammatory diseases, and erectile dysfunction in Israel. The company's lead drug candidate Piclidenoson, which has been completed Phase III clinical trial for the treatment of psoriasis. It develops Namodenoson that is in Phase III clinical trial for the treatment of liver cancer; and Phase IIa for the treatment of pancreatic cancer; as well as in Phase IIb trial for the treatment of metabolic associated steatohepatitis; and CF602, which is in pre-clinical trial for the treatment of erectile dysfunction. In addition, It offers cannabinoids for treatment of conditions associated with elevated expression of the A3 adenosine receptors. Further, the company develops commercial predictive biomarker blood test kit for A3AR. It has license and collaboration agreement with CMS Medical to develop, manufacture, and commercialize Piclidenoson and Namodenoson. The company was formerly known as Can-Fite Technologies Ltd. and changed its name to Can-Fite BioPharma Ltd. in January 2001. The company was incorporated in 1994 and is headquartered in Ramat Gan, Israel.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Can-Fite BioPharma Ltd reported revenue of 438K ILA in FY2025 versus 853K ILA in FY2021, a compound −15.3%/yr. Reported net income was −10.6M ILA in FY2025.

Growth Quality 0/100
Revenue growth is weak, negative or inconsistent.
Latest Revenue (FY 2025)
438K ILS
Latest YoY
−35.0%
Avg. revenue growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
−18.5%
Avg. revenue growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
−10.5%
Avg. revenue growth/yr (19Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
−16.3%
Value creation/yr We only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed
Revenue −15.3%/yr
FY21 853K ILA
FY22 810K ILA
FY23 743K ILA
FY24 674K ILA
FY25 438K ILA
Net income
FY21 −12.6M ILA
FY22 −10.2M ILA
FY23 −7.6M ILA
FY24 −7.9M ILA
FY25 −10.6M ILA

CANF screens 50% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "Can-Fite BioPharma Ltd Fair Value". https://www.fairvalue-calculator.com/stock/CANF

Peer Group

Biotechnology · 629 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 41 · Below median
Fair Value upside −50% · Below median
Return on assets -67% · Bottom 25%
Net margin (TTM) 0% · Above median
Revenue growth -43% · Bottom 25%

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 1.36× · Cheaper than median
P/S (TTM) 18.74× · Pricier than 75% of peers

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Aug 26, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $525.73 $278.78 -47%
Regeneron Pharmaceuticals, Inc REGN $797.99 $594.40 -26%
argenx SE ARGX €877.60 €292.84 -67%
Samsung Biologics Co 207940 1,549,000 KRW 1,055,793 KRW -32%
Alnylam Pharmaceuticals, Inc ALNY $228.61 $51.70 -77%
Royalty Pharma plc RPRX $60.58 $24.22 -60%
Celltrion, Inc 068270 202,000 KRW 74,519 KRW -63%
BeOne Medicines AG ONC $362.51 $111.35 -69%
Moderna, Inc MRNA $63.67 $12.77 -80%
BioNTech SE 22UA €80.60 €52.92 -34%

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Frequently asked questions

Is Can-Fite BioPharma Ltd (CANF) overvalued or undervalued?
As of Aug 26, 2026, our model estimates a fair value of 2.60 ILA versus a price of 5.17 ILA, about −50% (overvalued).
What is the fair value of CANF?
Our model-based fair value for Can-Fite BioPharma Ltd is 2.60 ILA (as of Aug 26, 2026), built from audited fundamentals. The current price: 5.17 ILA.
What is the quality score of CANF?
Can-Fite BioPharma Ltd has a Quality Score of 40/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Can-Fite BioPharma Ltd (CANF)?
Can-Fite BioPharma Ltd reported trailing-twelve-month revenue of about 405K ILS (latest available figure, as of Aug 26, 2026).
What is the net profit margin of CANF?
The net profit margin of Can-Fite BioPharma Ltd is about 0.0%, meaning it keeps roughly 0.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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