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Akeso, Inc (AKESF) Fair Value & Analysis

Healthcare · US · Market cap $10.5B

AI Akeso, Inc logo Akeso, Inc AKESF · US
Price$12.19
Fair Value$11.13
Upside-8.7%
Quality25/100
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Mixed Growth
Loss-making · -36.4% net margin
Low debt · negative free cash flow
Ranks above peers (6/10)
Narrow moat 12/100
Evidence: Low Range $7.35 – $13.91 Share as image

Fair value as of: Jul 14, 2026

From 1 valuation models · updated 27 days ago

Fair value updated Jul 14, 2026, revised from $4.33 to $11.13 (+157.0%) since Jun 24, 2026. Share price +2.4% over the past month.

Below-average quality, currently priced close to our fair value.

What matters now

  • The price sits close to our fair value, market and models broadly agree here, little valuation tension.
  • A fairly wide model range ($7.35 to $13.91) leaves room in how you read the outcome.
  • Evidence is limited here (fewer models, shorter history), so the fair value is a rougher estimate than usual.
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Price vs Fair Value (3 years)

$22.92 $4.30 Fair Value $11.13 May 2023 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 14, 2026.

How to read this chart

39‑month range $4.30 – $22.92 · fair‑value band $7.35 – $13.91 · the $12.19 price screens above the $11.13 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 14, 2026.

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Analysis

Akeso, Inc (AKESF) currently trades at $12.19, while our model-based Fair Value estimate is $11.13, implying the stock looks roughly 8.7% fairly valued today. The Quality Score stands at 25/100 (below-average quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: low).

Over the trailing twelve months, Akeso, Inc generated revenue of $3.1B at a net margin of -36.4%. Revenue grew 49.6% year over year. It earns a return on equity of -14.5%. Fundamentals as of Jul 14, 2026

Our scenario range runs from $7.35 (bear case) to $13.91 (bull case); at $12.19, the current price sits within that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 47% below its 52-week high and 11% above its 52-week low, currently below its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at -9%, AKESF screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
NCAV (Graham) $4.91 $6.58 $9.82 50
All 1 models by family
Asset-Based
NCAV (Graham) $4.91 $6.58 $9.82 50

Key figures & financial health

Revenue (TTM) $3.1B
Revenue growth (YoY) +49.6%
Net margin -36.4%
Return on equity -14.5%
Free cash flow −$1.7B FY2025
Operating margin -30.7%
More key figures
EPS (TTM) $-0.1800

Figures from reported company fundamentals · as of Jul 14, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 25/100

Of which business quality 30 · Market factors (momentum, volatility) 19

Profitability 6
Margins and returns on capital today
Quality Growth 46
Are margins and returns improving?
Cashflow 8
Earnings quality: real cash, not paper profit
Fin. Strength 67
Balance sheet, leverage, solvency risk
Investment 0
Disciplined investing over empire-building
Low Volatility 51
Calm price path (market factor)
Momentum 5
Price trend over the last 3–12 months (market factor)
52W Momentum 5
Distance to the 52-week high (market factor)
Net Issuance 53
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Akeso, Inc., a biopharmaceutical company, engages in the research, development, manufacture, and commercialization of antibody drugs worldwide.

Full company description

Akeso, Inc., a biopharmaceutical company, engages in the research, development, manufacture, and commercialization of antibody drugs worldwide. The company develops AK104, a PD-1/CTLA-4 bi-specific antibody to treat cervical cancer, gastric cancer, lung cancer, and liver cancer; and AK112, a PD-1/VEGF bi-specific antibody to treat lung cancer, biliary tract cancer, head and neck squamous cell carcinoma, breast cancer, colorectal cancer, and pancreatic cancer. It is also developing AK117, a CD47 monoclonal antibody to treat myelodysplastic syndrome, acute myeloid leukemia, and recurrent or refractory classical Hodgkin lymphoma; AK109, a PD-1 monoclonal antibody to treat G/GEJ patients; penpulimab, a PD-1 for the treatment of recurrent or metastatic nasopharyngeal carcinoma (NPC); and tagitanlimab, a PD-L1 for treating recurrent or metastatic NPC. In addition, the company develops AK102, a PCSK9 monoclonal antibody to treat hypercholesterolemia and mixed hyperlipidemia; AK101, an IL-12/IL-23 monoclonal antibody to treat moderate-to-severe psoriasis and ulcerative colitis; AK111, an IL-17 monoclonal antibody to treat moderate-to-severe psoriasis and ankylosing spondylitis; and AK120, an IL-4R monoclonal antibody to treat moderate-to-severe atopic dermatitis. Further, its preclinical product includes AK120 to treat moderate-to-severe atopic dermatitis. The company was founded in 2012 and is headquartered in Zhongshan, the People's Republic of China.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Akeso, Inc reported revenue of $3.1B in FY2025 versus $226M in FY2021, a compound +91.8%/yr. Reported net income was −$1.1B in FY2025.

Growth Quality 28/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$3.1B
Latest YoY
+43.9%
Avg. growth/yr (3Y)
+53.9%
Revenue +91.8%/yr
FY21 $226M
FY22 $838M
FY23 $4.5B
FY24 $2.1B
FY25 $3.1B
Net income
FY21 −$1.1B
FY22 −$1.2B
FY23 $2.0B
FY24 −$515M
FY25 −$1.1B

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Cite: Fair Value Calculator (2026). "Akeso, Inc Fair Value". https://www.fairvalue-calculator.com/stock/AKESF

Earlier news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 30 · Bottom 25%
Fair Value upside −9% · Above median
Return on assets -4% · Above median
Net margin (TTM) -36% · Bottom 25%
Operating margin (TTM) -31% · Bottom 25%
Revenue growth 50% · Top 25%
Debt / equity 0.44× · Higher than 75% of peers

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 1.16× · Cheaper than median
P/S (TTM) 3.42× · Cheaper than median

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 22 · sector 0
FUTURE 100 · sector 0
PAST 0 · sector 0
HEALTH 78 · sector 97
DIVIDEND 0 · sector 23

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 14, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is Akeso, Inc (AKESF) overvalued or undervalued?
As of Jul 14, 2026, our model estimates a fair value of $11.13 versus a price of $12.19, about −9% (fairly valued).
What is the fair value of AKESF?
Our model-based fair value for Akeso, Inc is $11.13 (as of Jul 14, 2026), built from audited fundamentals. The current price is $12.19.
What is the quality score of AKESF?
Akeso, Inc has a Quality Score of 25/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Akeso, Inc (AKESF)?
Akeso, Inc reported trailing-twelve-month revenue of about $3.1B (latest available figure, as of Jul 14, 2026).
What is the net profit margin of AKESF?
The net profit margin of Akeso, Inc is about -36.4%, meaning it is currently running at a net loss. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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