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AnaptysBio, Inc (ANAB) Fair Value & Analysis

Healthcare · US · Market cap $1.7B

AI AnaptysBio, Inc logo AnaptysBio, Inc ANAB · US
Price$56.61
Fair Value$26.66
Upside-52.9%
Quality57/100
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Mixed Growth
Loss-making · -11.5% net margin
Low debt · generates free cash flow
Trails peers (3/12)
Narrow moat 22/100
Evidence: High Range $19.22 – $31.71 Share as image

Fair value as of: Jul 15, 2026

From 15 valuation models · updated 25 days ago

Share price −13.4% over the past month.

A solid business, but screening 53% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($31.71). The favourable scenario is already priced in.
  • Solid but not exceptional quality (57/100) and above fair value, neither a clear bargain nor a standout compounder.
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Price vs Fair Value (5 years)

$69.81 $8.25 Fair Value $26.66 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 15, 2026.

How to read this chart

60‑month range $8.25 – $69.81 · fair‑value band $19.22 – $31.71 · the $56.61 price screens above the $26.66 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 15, 2026.

Full chart & analysis →

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Analysis

AnaptysBio, Inc (ANAB) currently trades at $56.61, while our model-based Fair Value estimate is $26.66, implying the stock looks roughly 52.9% overvalued today. The Quality Score stands at 57/100 (solid quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: high).

Over the trailing twelve months, AnaptysBio, Inc generated revenue of $232M at a net margin of -11.5%. Revenue declined 8.0% year over year. The balance sheet holds a net cash position of $224M. Fundamentals as of Jul 15, 2026

Our scenario range runs from $19.22 (bear case) to $31.71 (bull case); at $56.61, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 22% below its 52-week high and 396% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at -53%, ANAB screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Growth DCF $16.47 $22.62 $32.29 80
Rev-Margin DCF $23.34 $37.04 $65.57 74
ROIC Compounder $19.67 $21.26 $22.58 72
All 15 models by family
DCF Models
FCF DCF $17.04 $21.18 $33.57 38
5Y Revenue Exit $21.81 $33.42 $57.84 39
5Y EBITDA Exit $23.24 $36.31 $61.98 41
10Y Revenue Exit $19.71 $36.69 $48.45 36
10Y EBITDA Exit $21.22 $39.50 $72.05 37
Earnings-Based
EPV $19.67 $21.26 $22.58 59
Dividend Discount
Gordon GGM $3.08 $5.54 $7.63 70
DDM Multi-Stage $3.08 $5.06 $5.92 61
Multiples
EV/EBIT $28.65 $35.52 $42.40 53
EV/EBITDA $25.87 $31.82 $37.76 54
EV/Revenue $22.74 $29.05 $35.36 43
Asset-Based
NCAV (Graham) $0.6300 $0.8400 $1.26 50
Growth DCF
Growth DCF $16.47 $22.62 $32.29 80
Rev-Margin DCF $23.34 $37.04 $65.57 74
Economic Profit
ROIC Compounder $19.67 $21.26 $22.58 72

Widest divergence: DCF Models ($36.31) versus Asset-Based ($0.8400). Highest evidence: Growth DCF (80).

Key figures & financial health

Revenue (TTM) $232M
Revenue growth (YoY) -8.0%
Net margin -11.5%
Return on equity -115%
Free cash flow $19.6M FY2025
Operating margin -136%
More key figures
EPS (TTM) $-1.02
Net cash $224M FY2025

Figures from reported company fundamentals · as of Jul 15, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 57/100

Of which business quality 57 · Market factors (momentum, volatility) 71

Profitability 30
Margins and returns on capital today
Quality Growth 100
Are margins and returns improving?
Cashflow 61
Earnings quality: real cash, not paper profit
Fin. Strength 52
Balance sheet, leverage, solvency risk
Investment 100
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 76
Price trend over the last 3–12 months (market factor)
52W Momentum 87
Distance to the 52-week high (market factor)
Net Issuance 23
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory diseases in the United States.

Full company description

AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory diseases in the United States. The company's products include Rosnilimab, a selective pathogenic T cell deplete which completed a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis; ANB033, a CD122 antagonist, which is in a Phase 1b trial for celiac disease and eosinophilic esophagitis; ANB101, a BDCA2 modulator antibody which is in Phase 1a trial that specifically targets plasmacytoid dendritic cells and inhibits interferon secretion and modulates antigen presentation; dostarlimab, a PD-1 antagonist for various solid tumor indications; and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. It focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has collaborations agreement with GSK and Vanda. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

AnaptysBio, Inc reported revenue of $235M in FY2025 versus $63.2M in FY2021, a compound +38.8%/yr. Reported net income was −$13.2M in FY2025.

Growth Quality 67/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$235M
Latest YoY
+157.0%
Avg. growth/yr (3Y)
+183.6%
Avg. growth/yr (5Y)
+25.6%
Avg. growth/yr (12Y)
+36.8%
Revenue +38.8%/yr
FY21 $63.2M
FY22 $10.3M
FY23 $17.2M
FY24 $91.3M
FY25 $235M
Net income
FY21 −$57.8M
FY22 −$129M
FY23 −$164M
FY24 −$145M
FY25 −$13.2M

ANAB screens 53% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "AnaptysBio, Inc Fair Value". https://www.fairvalue-calculator.com/stock/ANAB

Earlier news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 57 · Above median
Fair Value upside −53% · Below median
Return on assets 7% · Top 25%
Net margin (TTM) -12% · Bottom 25%
Operating margin (TTM) -136% · Bottom 25%
Revenue growth -8% · Below median
Debt / equity 0.02× · Lower than median

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 44.60× · Pricier than 75% of peers
P/S (TTM) 7.14× · Pricier than median
P/FCF 84.6× · Pricier than 75% of peers
EV/EBITDA 34.4× · Pricier than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 0 · sector 0
FUTURE 0 · sector 0
PAST 0 · sector 0
HEALTH 99 · sector 97
DIVIDEND 0 · sector 23

VALUE 0: the price sits above our fair-value range.

Insider activity: 42/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 15, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is AnaptysBio, Inc (ANAB) overvalued or undervalued?
As of Jul 15, 2026, our model estimates a fair value of $26.66 versus a price of $56.61, about −53% (overvalued).
What is the fair value of ANAB?
Our model-based fair value for AnaptysBio, Inc is $26.66 (as of Jul 15, 2026), built from audited fundamentals. The current price is $56.61.
What is the quality score of ANAB?
AnaptysBio, Inc has a Quality Score of 57/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of AnaptysBio, Inc (ANAB)?
AnaptysBio, Inc reported trailing-twelve-month revenue of about $232M (latest available figure, as of Jul 15, 2026).
What is the net profit margin of ANAB?
The net profit margin of AnaptysBio, Inc is about -11.5%, meaning it is currently running at a net loss. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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