Structure Therapeutics Inc. (GPCR) fair value: what the stock is really worth
As of Sep 23, 2026: fair value of Structure Therapeutics Inc. $17.91, price $35.95, upside -50.2%, quality 36 out of 100. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 24, 2026.
How to read this chart
44‑month range $14.15 – $93.79 · fair‑value band $11.82 – $22.39 · the $35.95 price screens above the $17.91 fair value. Dashed = 300-day average. As of Sep 24, 2026.
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Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States.
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Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, which is in two phase 2 clinical trials for the treatment of obesity, overweight, and related conditions. The company also develops ACCG-2671 and ACCG-3535, an oral small molecule amylin receptor agonist that is in phase1 clinical trial for the treatment of obesity; ANPA-0073, an oral small molecule APJ receptor agonist; and LTSE-2578, an antagonist that targets lysophosphatidic acid 1 receptor, a G-protein coupled receptors implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of idiopathic pulmonary fibrosis. In addition, it develops programs, including glucose-dependent insulinotropic polypeptide receptor (GIPR) program, which identified multiple GIPR agonist, dual GLP-1R/GIPR agonist, and GIPR antagonist hits for small molecule GIPR modulation that has the potential to provide a treatment in obesity; and GCG program, which identified multiple GCG receptor (GCGR) agonist and dual GLP-1R/GCGR agonist hits for small molecule GCGR modulation. The company was formerly known as ShouTi Inc. Structure Therapeutics Inc. was incorporated in 2016 and is headquartered in South San Francisco, California.
Stock analysis
Structure Therapeutics Inc. American Depositary Shares (GPCR) currently trades at $35.95, while our model-based Fair Value estimate is $17.91, implying the stock looks roughly 100.7% overvalued today.
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Valuation
How firm this estimate is: it rests on 1 models at a data quality of 96/100, which puts the evidence level at low.
Scenario range: $11.82 (bear) to $22.39 (bull), the price of $35.95 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 36/100 (below-average quality), in the Healthcare sector.
Structure Therapeutics Inc. American Depositary Shares reported revenue of $0 in FY2025 versus $0 in FY2021. Reported net income was −$141M in FY2025.
Key figures
Market cap $2.6B · EPS (TTM) $−3.03 · Return on equity −20.2% · Return on assets (EBIT) −28.9% · Free cash flow −$226M · Net cash $793M.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 28 out of 100 (low confidence).
What moves the price
The share trades about 62% below its 52-week high and 50% above its 52-week low, currently below its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at −5% fair-value upside, at −50%, GPCR screens richer than that median.
Fair Value models
Bear $11.82Fair Value $17.91Bull $22.39
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above is their evidence-weighted blend, not the output of a single model.Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target.Evidence ⓘEvidence = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
News mood ⓘNews mood, the average tone of recent news (94 articles), rated against how stocks are usually covered. 🚀 Hype = unusually upbeat · 🙂 Positive = above average · 😐 Neutral = typical · 🙁 Negative = below average · 😨 Very negative = unusually downbeat. It reflects the tone of coverage, not our valuation.Positive
Recent news coverage is more positive than average.
Compare Structure Therapeutics Inc. American Depositary Shares with another stock
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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 651 stocks
Beats the industry median on 3/6 measures
A mixed picture versus its industry peers.
Valuation
Quality Score45 · Above median
Fair Value upside−50% · Below median
Profitability
Return on assets−15% · Below median
Operating margin (TTM)0% · Above median
Growth and dividend
Revenue growth0% · Above median
Valuation Multiplesvs Biotechnology median · lower = cheaper
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Cite: Fair Value Calculator (2026). "Structure Therapeutics Inc. American Depositary Shares Fair Value". https://www.fairvalue-calculator.com/stock/GPCR
Frequently asked questions
Is Structure Therapeutics Inc. (GPCR) overvalued or undervalued?
As of Sep 24, 2026, our model estimates a fair value of $17.91 versus a price of $35.95, about −50% upside (overvalued).
What is the fair value of GPCR?
Our model-based fair value for Structure Therapeutics Inc. American Depositary Shares is $17.91 (as of Sep 24, 2026), built from audited fundamentals. The current price: $35.95.
What is the quality score of GPCR?
Structure Therapeutics Inc. American Depositary Shares has a Quality Score of 36/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Structure Therapeutics Inc. (GPCR)?
Our model-based price target is the fair value of $17.91 (as of Sep 24, 2026) from 1 valuation models. Cautious scenario $11.82, optimistic scenario $22.39. It is a calculation from audited fundamentals, not an analyst target.
What is the Structure Therapeutics Inc. American Depositary Shares stock forecast for 2026?
Our models put fair value at $17.91, about −50% upside versus a price of $35.95 (overvalued). Cautious scenario $11.82, optimistic scenario $22.39. The calculation is refreshed regularly with new filings.
What is the intrinsic value of Structure Therapeutics Inc. (GPCR)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Structure Therapeutics Inc. American Depositary Shares it is $17.91 per share (as of Sep 24, 2026), against a price of $35.95. It is the blended result of 1 valuation models (cash flow, earnings, asset, dividend).
Is Structure Therapeutics Inc. American Depositary Shares stock overvalued or undervalued in 2026?
As of Sep 24, 2026, GPCR trades above its calculated fair value: price $35.95, fair value $17.91, a gap of about −50% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of GPCR?
No. The price is what the market pays today ($35.95); the fair value is what the company's own numbers justify ($17.91). For Structure Therapeutics Inc. American Depositary Shares the two are $18.04 per share apart. That gap is exactly why we show both numbers side by side.
How much is Structure Therapeutics Inc. American Depositary Shares worth?
The market values Structure Therapeutics Inc. American Depositary Shares at about $2.6B (market capitalisation, as of Sep 24, 2026). Per share that is $35.95; our models calculate a fair value of $17.91 per share.
What do the bullish and bearish scenarios say about GPCR?
Our models span a range for Structure Therapeutics Inc. American Depositary Shares: cautious scenario $11.82, base $17.91, optimistic $22.39 per share (as of Sep 24, 2026, price $35.95). The range comes from different growth and margin assumptions, not from analyst opinions.
How solid is the balance sheet of Structure Therapeutics Inc. (GPCR)?
Balance-sheet figures for Structure Therapeutics Inc. American Depositary Shares (as of Sep 24, 2026): return on equity −20.2%. They feed the Quality Score of 36/100, which measures business quality independently of the share price.
How far is GPCR from its 52-week high?
Structure Therapeutics Inc. American Depositary Shares trades at $35.95, about 62% below its 52-week high of $93.79 and 50% above the low of $24.01 (as of Sep 23, 2026). Distance from the high says nothing about value: that is what the fair value of $17.91 is for.
Which stocks are comparable to Structure Therapeutics Inc. American Depositary Shares?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, Samsung Biologics Co, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Structure Therapeutics Inc. American Depositary Shares stock attractive at the current price?
The data as of Sep 24, 2026: price $35.95, calculated fair value $17.91 (−50%), Quality Score 36/100, from 1 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of GPCR calculated?
We run Structure Therapeutics Inc. American Depositary Shares through 1 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of $17.91, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.1 % above its aggregate fair value. Structure Therapeutics Inc. American Depositary Shares itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Structure Therapeutics Inc. (GPCR)?
The closing price on Sep 23, 2026 was $35.95. Our model-based fair value is $17.91, about −50% upside (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Structure Therapeutics Inc. American Depositary Shares right now?
The price sits above even our optimistic bull case ($22.39). The favourable scenario is already priced in. Weak quality (36/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution. A fairly wide model range ($11.82 to $22.39) leaves room in how you read the outcome.
Key figures of Structure Therapeutics Inc. American Depositary Shares
How large is the market capitalisation of Structure Therapeutics Inc. (GPCR)?
The market capitalisation of Structure Therapeutics Inc. American Depositary Shares is $2.6B. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What are the earnings per share of Structure Therapeutics Inc. (GPCR)?
Earnings per share at Structure Therapeutics Inc. American Depositary Shares are $−3.03. Earnings per share over the last twelve months: total profit spread across every single share.
What is the return on equity of Structure Therapeutics Inc. (GPCR)?
The return on equity (ROE) of Structure Therapeutics Inc. American Depositary Shares is −20.2% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Structure Therapeutics Inc. (GPCR)?
On an EBIT basis the return on assets of Structure Therapeutics Inc. American Depositary Shares is −28.9% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
How much free cash flow does Structure Therapeutics Inc. (GPCR) generate?
The free cash flow of Structure Therapeutics Inc. American Depositary Shares is −$226M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net cash does Structure Therapeutics Inc. (GPCR) hold?
Structure Therapeutics Inc. American Depositary Shares holds more cash than debt, $793M net (fiscal year 2025). The company holds more cash than debt, a safety cushion.
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Thin data
Sep 24, 2026