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Harmony Biosciences Holdings (HRMY) Fair Value & Analysis

Healthcare · US · Market cap $2.1B

HB Harmony Biosciences Holdings logo Harmony Biosciences Holdings HRMY · US
Price$38.41
Fair Value$60.30
Upside+57.0%
Quality73/100
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Mixed Growth
Solidly profitable · 16.2% net margin
Low debt · generates free cash flow
Ranks above peers (10/13)
Wide moat 70/100
Evidence: High Range $45.23 – $123.91 Share as image

Fair value as of: Jul 12, 2026

From 26 valuation models · updated 28 days ago

Share price +0.9% over the past month.

A solid business, screening 57% undervalued on our models.

What matters now

  • The rarer combination: high quality (73/100) AND below fair value. That earns a closer look rather than a quick verdict.
  • The price is below even our cautious bear case ($45.23). The market is more pessimistic than our downside scenario.
  • The model range is unusually wide ($45.23 to $123.91). The outcome hinges heavily on assumptions, so read the point estimate with caution.
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Price vs Fair Value (5 years)

$60.91 $19.20 Fair Value $60.30 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 12, 2026.

How to read this chart

60‑month range $19.20 – $60.91 · fair‑value band $45.23 – $123.91 · the $38.41 price screens below the $60.30 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 12, 2026.

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Analysis

Harmony Biosciences Holdings (HRMY) currently trades at $38.41, while our model-based Fair Value estimate is $60.30, implying the stock looks roughly 57.0% undervalued today. The Quality Score stands at 73/100 (solid quality), in the Healthcare sector. Bull case: trading below our estimate, it may offer upside if the fundamentals hold. Bear case: a low price can be a value trap when quality is weak or the data is thin (evidence: high), always confirm before acting.

Over the trailing twelve months, Harmony Biosciences Holdings generated revenue of $899M at a net margin of 16.2%. Revenue grew 16.6% year over year. It earns a return on equity of 17.9%. The balance sheet holds a net cash position of $513M. Fundamentals as of Jul 12, 2026

Our scenario range runs from $45.23 (bear case) to $123.91 (bull case); at $38.41, the current price sits below that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 6% below its 52-week high and 51% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at 57%, HRMY screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Growth DCF $100.27 $181.36 $312.00 80
Residual Income $17.81 $25.20 $119.52 76
Rev-Margin DCF $67.72 $105.07 $183.81 74
All 26 models by family
DCF Models
FCF DCF $106.09 $157.67 $318.49 38
Owner Earnings $57.64 $114.94 $230.83 31
5Y Revenue Exit $62.76 $93.07 $155.84 39
5Y EBITDA Exit $69.15 $105.98 $177.89 41
5Y P/E Exit $71.23 $133.62 $216.49 38
10Y Revenue Exit $75.25 $134.18 $165.97 36
10Y EBITDA Exit $81.17 $147.62 $257.05 37
10Y P/E Exit $82.66 $152.00 $261.03 35
Earnings-Based
Graham-Dodd $18.64 $129.99 $182.42 54
Lynch FV $67.16 $95.94 $124.72 50
PEG = 1.0 $67.16 $95.94 $124.72 46
EPV $34.40 $38.17 $41.42 59
Dividend Discount
Gordon GGM $0.7700 $1.53 $2.31 70
DDM Multi-Stage $0.7700 $1.32 $1.61 61
Multiples
P/E Multiple $45.23 $60.30 $75.38 63
P/S Multiple $34.95 $46.60 $58.25 58
P/B Multiple $34.95 $46.60 $58.25 55
EV/EBIT $56.43 $71.73 $87.04 53
EV/EBITDA $52.92 $67.06 $81.19 54
EV/Revenue $42.02 $55.52 $69.02 43
Asset-Based
NCAV (Graham) $7.52 $10.07 $15.03 50
Growth DCF
Growth DCF $100.27 $181.36 $312.00 80
Rev-Margin DCF $67.72 $105.07 $183.81 74
Economic Profit
Residual Income $17.81 $25.20 $119.52 76
ROIC Compounder $39.63 $51.91 $67.13 72
Growth Earnings
Growth-Adj P/E $89.14 $127.35 $165.55 68

Widest divergence: DCF Models ($133.62) versus Dividend Discount ($1.32). Highest evidence: Growth DCF (80).

Key figures & financial health

Revenue (TTM) $899M
Revenue growth (YoY) +16.6%
Net margin 16.2%
Return on equity 17.9%
Free cash flow $348M FY2025
P/E ratio 14.9
More key figures
Operating margin 17.3%
EPS (TTM) $2.48
EPS growth (YoY) -29.5%
Net cash $513M FY2025

Figures from reported company fundamentals · as of Jul 12, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 73/100

Of which business quality 75 · Market factors (momentum, volatility) 54

Profitability 72
Margins and returns on capital today
Quality Growth 42
Are margins and returns improving?
Cashflow 100
Earnings quality: real cash, not paper profit
Fin. Strength 94
Balance sheet, leverage, solvency risk
Investment 33
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 52
Price trend over the last 3–12 months (market factor)
52W Momentum 63
Distance to the 52-week high (market factor)
Net Issuance 83
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Harmony Biosciences Holdings, Inc., a commercial-stage pharmaceutical company, focuses on developing and commercializing therapies for patients with rare neurological diseases in the United States.

Full company description

Harmony Biosciences Holdings, Inc., a commercial-stage pharmaceutical company, focuses on developing and commercializing therapies for patients with rare neurological diseases in the United States. The company offers WAKIX (pitolisant), a molecule with a novel mechanism of action for the treatment of excessive daytime sleepiness in adult patients with narcolepsy. It also develops Pitolisant that is in Phase 3 clinical trial for the treatment of Prader-Willi Syndrome (PWS); in Phase 2 clinical trial to treat Myotonic Dystrophy (DM1); and is in Phase 2 clinical trials for the treatment of Pitolisant Gastro-Resistant (GR) and Pitolisant High-Dose (HD). In addition, the company's products under development include BP1.15205, an orexin 2 receptor agonist for the treatment of narcolepsy and other potential indications; and HBS-102, a melanin-concentrating hormone receptor type 1 (MCHR1) antagonist. Further, it develops ZYN-002 that is in a Phase 3 registrational trial for the treatment of Fragile X Syndrome; and 22q Deletion Syndrome, a disorder caused by a small missing piece on the long arm of the 22nd chromosome. Additionally, the company is developing EPX-100 (clemizole hydrochloride), a serotonin (5HT-2) receptor agonist to treat dravet syndrome and lenox-gastaut syndrome; EPX-200 (liquid formulation of lorcaserin), a selective 5HT-2C agonist to treat developmental and epileptic encephalopathies; CBS105 for the treatment-resistant narcolepsy; and CBS104 for refractory epilepsy. The company was formerly known as Harmony Biosciences II, Inc. and changed its name to Harmony Biosciences Holdings, Inc. in February 2020. Harmony Biosciences Holdings, Inc. was incorporated in 2017 and is headquartered in Plymouth Meeting, Pennsylvania.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Harmony Biosciences Holdings reported revenue of $868M in FY2025 versus $305M in FY2021, a compound +29.9%/yr. Reported net income was $159M in FY2025, compounding +46.3%/yr from FY2021.

Growth Quality 91/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$868M
Latest YoY
+21.5%
Avg. growth/yr (3Y)
+25.6%
Avg. growth/yr (5Y)
+40.3%
Avg. growth/yr (6Y)
+129.2%
Revenue +29.9%/yr
FY21 $305M
FY22 $438M
FY23 $582M
FY24 $715M
FY25 $868M
Net income +46.3%/yr
FY21 $34.6M
FY22 $181M
FY23 $129M
FY24 $145M
FY25 $159M

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Cite: Fair Value Calculator (2026). "Harmony Biosciences Holdings Fair Value". https://www.fairvalue-calculator.com/stock/HRMY

Earlier news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 73 · Top 25%
Fair Value upside +57% · Top 25%
Return on equity (TTM) 18% · Top 25%
Return on assets 10% · Top 25%
Net margin (TTM) 16% · Top 25%
Operating margin (TTM) 17% · Top 25%
Revenue growth 17% · Above median
Debt / equity 0.17× · Higher than median

Valuation Multiples vs Biotechnology median · lower = cheaper

P/E (TTM) 14.9× · Cheaper than median
P/B 2.45× · Pricier than median
P/S (TTM) 2.37× · Cheaper than median
P/FCF 6.1× · Pricier than median
EV/EBITDA 7.1× · Cheaper than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 100 · sector 0
FUTURE 83 · sector 0
PAST 71 · sector 0
HEALTH 92 · sector 97
DIVIDEND 0 · sector 23

Insider activity: 45/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 12, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is Harmony Biosciences Holdings (HRMY) overvalued or undervalued?
As of Jul 12, 2026, our model estimates a fair value of $60.30 versus a price of $38.41, about +57% (undervalued).
What is the fair value of HRMY?
Our model-based fair value for Harmony Biosciences Holdings is $60.30 (as of Jul 12, 2026), built from audited fundamentals. The current price is $38.41.
What is the quality score of HRMY?
Harmony Biosciences Holdings has a Quality Score of 73/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Harmony Biosciences Holdings (HRMY)?
Harmony Biosciences Holdings reported trailing-twelve-month revenue of about $899M (latest available figure, as of Jul 12, 2026).
What is the net profit margin of HRMY?
The net profit margin of Harmony Biosciences Holdings is about 16.2%, meaning it keeps roughly 16.2% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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