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Intellia Therapeutics Inc (NTLA) fair value: what the stock is really worth

As of Nov 6, 2026: fair value (intrinsic value) of Intellia Therapeutics Inc stock $2.17, price $11.35, that is 80.9% below the price, quality 32 out of 100. Rating: strongly overvalued. Calculated from audited financials with one of our 26 valuation models and 37 quality factors, updated daily.

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Healthcare US

IT Intellia Therapeutics Inc logo Thin data Nov 6, 2026

Intellia Therapeutics Inc

NTLA · US
Very expensive, weak quality

Our calculation puts a fair price 81% below what the stock costs today.

Low debt
Mixed Growth (revenue 5y +3.1 %/yr in USD)
Neutral coverage
Insiders sold $637,649 (6M)
Revenue last quarter 46% below a year ago.
Fair value $2.17 · Strongly overvalued (−80.9%)
Quality 32/100
Negative free cash flow
Trails peers (1/8)
Narrow moat 9/100
Thin data
⚠ Dilution
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Price vs Fair Value

$176.78 $6.28 Fair Value $2.17 Aug 2021 Nov 2026

White line = price, green steps = our fair value per fiscal year. As of Nov 6, 2026.

How to read this chart

60‑month range $6.28 – $176.78 · fair‑value band $1.43 – $2.70 · the $11.35 price screens above the $2.17 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 6, 2026.

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Company profile

Intellia Therapeutics, Inc. operates as a clinical-stage genome editing company focused on developing potentially curative therapeutics using CRISPR/Cas9-based technologies.

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The company offers clustered, regularly interspaced short palindromic repeats ("CRISPR")/CRISPR associated 9 ("Cas9") technology for genome editing. The company provides a modular platform, to advance in vivo and ex vivo therapies for diseases.

The company's in vivo product candidates include nexiguran ziclumeran, or NTLA-2001 for the treatment of transthyretin amyloidosis; and NTLA-2002 for the treatment of hereditary angioedema.

Additionally, it offers product candidates for the treatment of immuno-oncology and autoimmune diseases, and multiple in vivo programs to address diseases with significant unmet medical need by delivering gene editing therapeutics to organs outside the liver.

The company has license and collaboration agreement with AvenCell Therapeutics, Inc. to develop allogeneic universal CAR-T cell therapies; Kyverna Therapeutics, Inc. for the development of an allogeneic CD19 CAR-T cell therapy for the treatment of various of B cell-mediated autoimmune diseases; ONK Therapeutics, Ltd. for the development of engineered NK cell therapies to cure patients with cancer; and ReCode Therapeutics, Inc. to develop novel genomic medicines for the treatment of cystic fibrosis.

It also has collaboration agreements with Regeneron Pharmaceuticals, Inc., SparingVision SAS, and Rewrite Therapeutics Inc. The company was formerly known as AZRN, Inc. and changed its name to Intellia Therapeutics, Inc. in July 2014.

Intellia Therapeutics, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.

Stock analysis

Intellia Therapeutics Inc (NTLA) currently trades at $11.35, while our model-based Fair Value estimate is $2.17, 81% below the price, so the stock looks overvalued today.

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Valuation

How firm this estimate is: it rests on 1 models at a data quality of 96/100, which puts the data coverage at low.

Scenario range: $1.43 (bear) to $2.70 (bull), the price of $11.35 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 32/100 (below-average quality), in the Healthcare sector.

Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.

Intellia Therapeutics Inc reported revenue of $67.7M in FY2025 versus $33.1M in FY2021, a compound +19.6%/yr. Reported net income was −$413M in FY2025.

Key figures

Market cap $1.5B Small · P/S ratio 26.1 · EPS (TTM) $−3.35 · Return on equity −55.4% · Return on assets (EBIT) −37.5% (5-year average) · Operating margin −1,472% · Revenue (TTM) $59.5M · Revenue growth (YoY) −46.2%.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 9 out of 100 (medium confidence).

What moves the price

The share trades about 36% below its 52-week high and 41% above its 52-week low, currently below its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at 10% fair-value upside, at −81%, NTLA screens richer than that median.

Fair Value models

Bear $1.43 Fair Value $2.17 Bull $2.70
Price $11.35 · Downside -80.9%
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above starts from their evidence-weighted blend, not from a single model. In cyclical trough or peak years, after dilution or a stock split it is adjusted afterwards, so it can sit above or below the models. Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. If a model's bull case is above four times its base value, the table shows that limit with a > sign (like the overall Bull above): beyond it no assumption holds. Coverage ⓘCoverage = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
Best data coverage
NCAV (Graham) $1.68 $2.55 $3.18 55
All 1 models by family
Asset-Based
NCAV (Graham) $1.68 $2.55 $3.18 55

The fair value above starts from this blend and is adjusted for dilution from new shares.

Open the full fair value analysis →

Quality Score breakdown

Overall quality 32/100

It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.

Profitability 2
How much profit the company makes from its sales and capital
Quality Growth 48
Are margins and returns getting better?
Cashflow 8
Do the profits arrive as real cash?
Financial strength 65
Debt, balance sheet and risk of trouble
Investment 88
Does it invest with discipline instead of growing at any price?
Low Volatility 0
How calm the share price moves, does not count
Price momentum 28
Price momentum of the last 3 to 12 months, does not count
Near the 52-week high 25
Distance to the 52-week high, does not count
New shares 0
Buys back shares or issues new ones?

Open the full quality analysis →

Insider trades

In the last 6 months, 3 officers or directors sold shares worth $637,649 and none bought.

  • SaleJohn M LeonardPresident and CEO, Director4× since Dec 11, 2025: 153,967 shares, avg. $10.04$1.5MNov 2, 2026
  • SaleMichael P DubeVP, Chief Accounting Officer3× since Jan 5, 2026: 7,494 shares, avg. $12.68$95,014Oct 2, 2026
  • SaleEdward J Dulac IIIEVP, Chief Financial Officer3× since Jan 5, 2026: 19,167 shares, avg. $12.22$234,185Jul 22, 2026
  • SaleEliana ClarkEVP, Chief Technical Officer2× since Jan 5, 2026: 10,122 shares, avg. $9.48$95,998Mar 2, 2026
  • SaleJames BastaEVP, General Counsel2× since Jan 5, 2026: 11,608 shares, avg. $9.69$112,444Mar 2, 2026
  • SaleDavid LebwohlEVP, Chief Medical Officer11,903 shares at $9.21$109,627Jan 5, 2026
  • BuyFred E CohenDirector150,000 shares at $9.35$1.4MJan 5, 2026
  • SaleBirgit C SchultesEVP, Chief Scientific Officer8,508 shares at $9.21$78,359Jan 5, 2026

Plus 8 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.

Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.

Source: SEC Form 4, as of Nov 6, 2026. All filings at the SEC ↗

Revenue & earnings trend

Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card. 9/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Revenue growth 1 year
+16.9%
Revenue growth 3 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+9.1%
Revenue growth 5 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+3.1%
Start year 2020 (pandemic). Over 10 years: +27.3% a year
Revenue growth 10 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+27.3%
Profit margin (trend) ⓘOperating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−235.5% (2020) → −651.7% (2025)
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

NTLA screens overvalued: fair value 81% below the price. Compare with Vertex Pharmaceuticals Incorporated →

Earlier news

News mood ⓘNews mood, the average tone of recent news (94 articles), rated against how stocks are usually covered. 🚀 Hype = unusually upbeat · 🙂 Positive = above average · 😐 Neutral = typical · 🙁 Negative = below average · 😨 Very negative = unusually downbeat. It reflects the tone of coverage, not our valuation. Neutral
Recent news coverage is roughly neutral, about typical for how stocks are covered.

Compare Intellia Therapeutics Inc with another stock

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 558 stocks

Beats the industry median on 0/6 measures
Overall it trails its industry peers.
Valuation
Quality Score 32 · Bottom 25%
Fair Value upside −80.9% · Bottom 25%
Profitability
Return on assets −49.0% · Bottom 25%
Growth and dividend
Revenue growth (quarter YoY) −46.2% · Bottom 25%

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/B 2.26× · Pricier than median
P/S (12 months) 25.46× · Priciest 25%

Strength profile in five axes (Snowflake)

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE (fair-value potential)0 · sector 0
FUTURE (revenue growth)0 · sector 0
PAST (return on equity)0 · sector 0
HEALTH (low debt)100 · sector 97
DIVIDEND (yield)0 · sector 22

VALUE 0: the price sits above our fair-value range.

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value Compare
Incyte Corporation INCY $119.65 $199.23 +67% vs NTLA
Regeneron Pharmaceuticals, Inc REGN $904.35 $1,275 +41% vs NTLA
Genmab A/S GMAB kr 3,527 kr 3,999 +13% vs NTLA
Samsung Biologics Co 207940 1,516,000 KRW 1,667,600 KRW +10% vs NTLA
WuXi Biologics (Cayman) Inc 2269 HK$47.62 HK$52.38 +10% vs NTLA
Vertex Pharmaceuticals Incorporated VRTX $547.09 $596.75 +9% vs NTLA
argenx SE ARGX $927.21 $908.40 −2% vs NTLA
CSL Limited CSL A$202.04 A$183.04 −9% vs NTLA
Celltrion, Inc 068270 211,000 KRW 74,945 KRW −64% vs NTLA
Royalty Pharma plc RPRX $67.30 $19.01 −72% vs NTLA

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Intellia Therapeutics Inc: fair value per Fair Value Calculator

Cite: Fair Value Calculator (2026). "Intellia Therapeutics Inc Fair Value". https://www.fairvalue-calculator.com/stock/NTLA

Frequently asked questions

Is Intellia Therapeutics Inc (NTLA) overvalued or undervalued?
As of Nov 6, 2026, our model estimates a fair value of $2.17 versus a price of $11.35, about 81% lower (overvalued).
What is the fair value of NTLA?
Our model-based fair value for Intellia Therapeutics Inc is $2.17 (as of Nov 6, 2026), built from audited fundamentals. The current price: $11.35.
What is the quality score of NTLA?
Intellia Therapeutics Inc has a Quality Score of 32/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Intellia Therapeutics Inc (NTLA)?
Our model-based price target is the fair value of $2.17 (as of Nov 6, 2026) from 1 valuation models. Cautious scenario $1.43, optimistic scenario $2.70. It is a calculation from audited fundamentals, not an analyst target.
What is the Intellia Therapeutics Inc stock forecast for 2026?
Our models put fair value at $2.17, about 81% lower versus a price of $11.35 (overvalued). Cautious scenario $1.43, optimistic scenario $2.70. The calculation is refreshed regularly with new filings.
What is the revenue of Intellia Therapeutics Inc (NTLA)?
Intellia Therapeutics Inc reported trailing-twelve-month revenue of about $59.5M (latest available figure, as of Nov 6, 2026).
What is the intrinsic value of Intellia Therapeutics Inc (NTLA)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Intellia Therapeutics Inc it is $2.17 per share (as of Nov 6, 2026), against a price of $11.35. It is the blended result of 1 valuation models in 1 family (Asset-Based).
Is Intellia Therapeutics Inc stock overvalued or undervalued in 2026?
As of Nov 6, 2026, NTLA trades above its calculated fair value: price $11.35, fair value $2.17, a gap of about −81% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of NTLA?
No. The price is what the market pays today ($11.35); the fair value is what the company's own numbers justify ($2.17). For Intellia Therapeutics Inc the two are $9.18 per share apart. That gap is exactly why we show both numbers side by side.
How much is Intellia Therapeutics Inc worth?
The market values Intellia Therapeutics Inc at about $1.5B (market capitalisation, as of Nov 6, 2026). Per share that is $11.35; our models calculate a fair value of $2.17 per share.
What do the bullish and bearish scenarios say about NTLA?
Our models span a range for Intellia Therapeutics Inc: cautious scenario $1.43, base $2.17, optimistic $2.70 per share (as of Nov 6, 2026, price $11.35). The range comes from different growth and margin assumptions, not from analyst opinions.
How solid is the balance sheet of Intellia Therapeutics Inc (NTLA)?
Balance-sheet figures for Intellia Therapeutics Inc (as of Nov 6, 2026): return on equity −55.4%. They feed the Quality Score of 32/100, which measures business quality independently of the share price.
How far is NTLA from its 52-week high?
Intellia Therapeutics Inc trades at $11.35, about 36% below its 52-week high of $17.84 and 41% above the low of $8.04 (as of Nov 6, 2026). Distance from the high says nothing about value: that is what the fair value of $2.17 is for.
Which stocks are comparable to Intellia Therapeutics Inc?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, CSL Limited, argenx SE, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Intellia Therapeutics Inc stock attractive at the current price?
The data as of Nov 6, 2026: price $11.35, calculated fair value $2.17 (−81%), Quality Score 32/100, from 1 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of NTLA calculated?
We run Intellia Therapeutics Inc through 1 models from 1 family: Asset-Based. Every model gets the same audited fundamentals; the fair value of $2.17 builds on their evidence-weighted average, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 13.0% above its aggregate fair value. Intellia Therapeutics Inc itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Intellia Therapeutics Inc (NTLA)?
The closing price on Nov 6, 2026 was $11.35. Our model-based fair value is $2.17, about 81% lower (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Intellia Therapeutics Inc right now?
The price sits above even our optimistic bull case ($2.70). The favourable scenario is already priced in. Weak quality (32/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution. A fairly wide model range ($1.43 to $2.70) leaves room in how you read the outcome.

Key figures of Intellia Therapeutics Inc

How large is the market capitalisation of Intellia Therapeutics Inc (NTLA)?
The market capitalisation of Intellia Therapeutics Inc is $1.5B. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What is the P/S ratio of Intellia Therapeutics Inc (NTLA)?
The price-to-sales ratio of Intellia Therapeutics Inc is 26.1 (last twelve months). Price to sales: market value relative to yearly revenue. Useful when profit is thin or distorted.
What are the earnings per share of Intellia Therapeutics Inc (NTLA)?
Earnings per share at Intellia Therapeutics Inc are $−3.35. Earnings per share over the last twelve months: total profit spread across every single share.
What is the return on equity of Intellia Therapeutics Inc (NTLA)?
The return on equity (ROE) of Intellia Therapeutics Inc is −55.4% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Intellia Therapeutics Inc (NTLA)?
On an EBIT basis the return on assets of Intellia Therapeutics Inc is −37.5% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
What is the operating margin of Intellia Therapeutics Inc (NTLA)?
The operating margin of Intellia Therapeutics Inc is −1,472% (last twelve months). Profit from the core business (before interest and taxes) relative to revenue.
How fast is revenue growing at Intellia Therapeutics Inc (NTLA)?
Revenue at Intellia Therapeutics Inc is growing −46.2% versus a year earlier (3y avg +9.1%). How much revenue grew versus a year earlier (YoY). The 3-year average next to it puts the single year in context.
How much free cash flow does Intellia Therapeutics Inc (NTLA) generate?
The free cash flow of Intellia Therapeutics Inc is −$355M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net cash does Intellia Therapeutics Inc (NTLA) hold?
Intellia Therapeutics Inc holds more cash than debt, $62.1M net (fiscal year 2025). The company holds more cash than debt, a safety cushion.
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