Halozyme Therapeutics Inc (HALO) fair value: what the stock is really worth
As of Nov 6, 2026: fair value (intrinsic value) of Halozyme Therapeutics Inc stock $128, price $104, upside +23.5%, quality 79 out of 100. Rating: undervalued. Calculated from audited financials with 22 of our 26 valuation models and 37 quality factors, updated daily.
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Halozyme Therapeutics Inc
HALO · USThe stock costs 19% less than our calculation considers fair.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 7, 2026.
How to read this chart
60‑month range $30.28 – $131.18 · fair‑value band $57.13 – $168.63 · the $103.63 price screens below the $127.95 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 7, 2026.
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Company profile
Halozyme Therapeutics, Inc., a biopharmaceutical company, researches, develops, and commercializes of proprietary enzymes and devices in the United States, Switzerland, Belgium, Japan, and internationally.
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The company's products are based on the patented recombinant human hyaluronidase enzyme (rHuPH20) that enables delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids.
It offers Hylenex recombinant, a formulation of rHuPH20 that facilitates subcutaneous (SC) administration to enhance the dispersion and absorption of other injected drugs in SC urography and to enhance resorption of radiopaque agents; and XYOSTED, an injection for SC administration of testosterone replacement therapy.
The company also provides Herceptin (trastuzumab) under the brand name Herceptin Hylecta; and Phesgo to treat breast cancer; Mabthera SC for chronic lymphocytic leukemia treatment; Tecentriq SC for IV infusion; Ocrevus SC for multiple sclerosis; HYQVIA to treat primary immunodeficiency disorders; DARZALEX to treat amyloidosis, and smoldering and multiple myeloma; epinephrine Injection to treat allergic reactions; nivolumab and relatlimab to treat metastatic or unresectable melanoma; teriparatide injections; ARGX-113; and ARGX-117 to treat severe autoimmune diseases in multifocal motor neuropathy.
It has collaborations and licensing agreements with F. Hoffmann-La Roche, Ltd. and Hoffmann-La Roche, Inc.; Takeda Pharmaceuticals International AG and Baxalta US Inc.; Pfizer Inc.; Janssen Biotech, Inc.; AbbVie, Inc.; Eli Lilly and Company; Bristol Myers Squibb Company; argenx BVBA; ViiV Healthcare; Chugai Pharmaceutical Co., Ltd.; Acumen Pharmaceuticals, Inc.; Merus N.V.; and Skye Bioscience, Inc. The company was founded in 1998 and is headquartered in San Diego, California.
Stock analysis
Halozyme Therapeutics Inc (HALO) currently trades at $103.63, while our model-based Fair Value estimate is $127.95, implying the stock looks roughly 19% undervalued today.
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Valuation
Bull case: the Growth Earnings group reads highest at a median of $129.72 per share, and 9 of the 22 models we run sit above the $103.63 price.
Bear case: the Economic Profit group reads lowest at $51.61, and 13 of the 22 models stay below the price. Data coverage for this calculation is medium.
Scenario range: $57.13 (bear) to $168.63 (bull), the price of $103.63 sits inside it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 79/100 (high quality), in the Healthcare sector.
Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.
Halozyme Therapeutics Inc reported revenue of $1.4B in FY2025 versus $443M in FY2021, a compound +33.2%/yr. Reported net income was $317M in FY2025, compounding −5.8%/yr from FY2021.
Key figures
Market cap $14.0B Large · P/E ratio 30.3 · P/S ratio 8.39 · EPS (TTM) $3.42 · Net margin 24.9% · Return on equity 174% · Return on assets (EBIT) 23.6% (5-year average) · Operating margin 59.8%.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 89 out of 100 (low confidence).
What moves the price
The last reported earnings sit well below what analysts expect (earnings in transition, for example after write-downs or an earnings dip); whether the stock is cheap or expensive hinges on the expected recovery actually arriving. Read the fair value with that caveat.
The share trades about 21% below its 52-week high and 68% above its 52-week low, currently above its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at 10% fair-value upside, at 23%, HALO screens cheaper than that median.
Fair Value models
All 22 models by family
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Insider trades
In the last 6 months, 4 officers or directors sold shares worth $29.8M and none bought.
- SaleHelen TorleyPRESIDENT AND CEO, Director12× since Nov 10, 2025: 508,492 shares, avg. $82.89$42.1MOct 8, 202610b5-1 plan
- SaleMatthew L. PosardDirector2× since Sep 16, 2026: 24,226 shares, avg. $107.91$2.6MOct 1, 202610b5-1 plan
- SaleBernadette ConnaughtonDirector7× since Nov 10, 2025: 11,330 shares, avg. $74.08$839,372Aug 10, 202610b5-1 plan
- SaleMahesh KrishnanDirector7,304 shares at $75.00$547,800Jun 29, 202610b5-1 plan
- SaleCortney CaudillSVP, CHIEF OPERATING OFFICER28,857 shares at $67.75$2.0MMar 10, 2026
Plus 11 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.
Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.
Source: SEC Form 4, as of Nov 6, 2026. All filings at the SEC ↗
Revenue & earnings trend
Growth Forecast
Watch HALO, get fair value alerts →
Recent news
- Halozyme Therapeutics (HALO) Following Record Results And Higher Guidance Is The Stock Still Undervalued
- Halozyme Stocks Slip 4.28% Despite 39% Revenue Growth and Modestly Higher Guidance
- Halozyme Stock Down Despite Q3 Earnings and Revenue Beat
- Halozyme Reaffirms It Projects Zero to Minimal Impact to Royalty Revenue Through At Least 2035 Based on Medicare Drug Price Negotiation Prog
Compare Halozyme Therapeutics Inc with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 558 stocks
Valuation Multiplesvs Biotechnology median · lower = cheaper
Strength profile in five axes (Snowflake)
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
- P/S ratio by industry
- EBIT margin by industry
- Stock screener with 62 metrics
- Undervalued stocks: US Stocks
- Valuation of the USA market
Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Biotechnology stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| Incyte Corporation INCY | $119.65 | $199.23 | +67% | vs HALO |
| Regeneron Pharmaceuticals, Inc REGN | $904.35 | $1,275 | +41% | vs HALO |
| Genmab A/S GMAB | kr 3,527 | kr 3,999 | +13% | vs HALO |
| Samsung Biologics Co 207940 | 1,516,000 KRW | 1,667,600 KRW | +10% | vs HALO |
| WuXi Biologics (Cayman) Inc 2269 | HK$47.62 | HK$52.38 | +10% | vs HALO |
| Vertex Pharmaceuticals Incorporated VRTX | $547.09 | $596.75 | +9% | vs HALO |
| argenx SE ARGX | $927.21 | $908.40 | −2% | vs HALO |
| CSL Limited CSL | A$202.04 | A$183.04 | −9% | vs HALO |
| Celltrion, Inc 068270 | 211,000 KRW | 74,945 KRW | −64% | vs HALO |
| Royalty Pharma plc RPRX | $67.30 | $19.01 | −72% | vs HALO |
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Key figures of Halozyme Therapeutics Inc
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