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Appili Therapeutics Inc (APLI) Fair Value & Analysis

Healthcare · CA · Market cap C$2.0M (≈ $1.4M) · ISIN CA03783R1073

What is Appili Therapeutics Inc really worth?

AT Appili Therapeutics Inc APLI · TO
PriceC$0.0100
Fair ValueC$0.0143
Upside+43.0%
Quality31/100

Below-average quality, trading 30% below our fair value of C$0.0143.

As of Jun 26, 2026, the fair value of Appili Therapeutics Inc is C$0.0143 per share against a price of C$0.0100, so the fair value sits 43% above the price. A model estimate blended from multiple valuation models, recalculated regularly.

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Strengths

Ranks above peers (5/6)

Risks

!Weak Growth (revenue 5y +4.2 %/yr)
!Thin margins · 0.0% net margin
!Negative equity (buybacks among others) · negative free cash flow
!Narrow moat 23/100
!Evidence only low, so the estimate is less certain
Evidence: Low Range C$0.0143 – C$0.0143

Fair value as of: Jun 26, 2026

From 6 valuation models · updated 71 days ago

Fair value updated Jun 26, 2026, revised from C$0.0100 to C$0.0143 (+43.0%) since Jun 24, 2026. Share price −33.3% over the past month.

What runs behind every stock

69 individual criteria per stock, every one traceable See the method →

What matters now

  • The large discount to fair value meets weak quality (31/100). That raises the risk this is a value trap rather than a bargain.
  • The price is below even our cautious bear case (C$0.0143). The market is more pessimistic than our downside scenario.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.

Price vs Fair Value (5 years)

C$1.08 C$0.0100 Fair Value C$0.0143 May 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jun 26, 2026.

How to read this chart

60‑month range C$0.0100 – C$1.08 · the C$0.0100 price screens below the C$0.0143 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jun 26, 2026.

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Analysis

Appili Therapeutics Inc (APLI) currently trades at C$0.0100, while our model-based Fair Value estimate is C$0.0143, implying the stock looks roughly 30.1% undervalued today. The Quality Score stands at 31/100 (below-average quality), in the Healthcare sector. How firm this estimate is: it rests on 6 models at a data quality of 95/100, which puts the evidence level at low.

Trailing-twelve-month revenue stands at C$206K. Revenue grew 6.1% year over year. Net debt stands at C$12.9M. Fundamentals as of Jun 26, 2026

The share trades about 75% below its 52-week high, currently below its 200-day average. For context, the median of 10 Healthcare peers we cover trades at −56% fair-value upside, at 43%, APLI screens cheaper than that median.

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Key figures & financial health

P/S ratio 9.33 TTM
EPS (TTM) C$−0.0200
Return on equity −939% TTM
Return on assets (EBIT) −207% avg 5y
Operating margin −624% TTM
Revenue (TTM) C$206K TTM
More key figures
Growth
Revenue growth (YoY) +6.1% 3y avg −9.9%
Balance sheet & cash flow
Free cash flow −C$1.4M FY2026
Net debt C$12.9M FY2026

Figures from reported company fundamentals · as of Jun 26, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 31/100

Of which business quality 26 · Market factors (momentum, volatility) 17

Profitability 6
Margins and returns on capital today
Quality Growth 42
Are margins and returns improving?
Cashflow 0
Earnings quality: real cash, not paper profit
Fin. Strength 2
Balance sheet, leverage, solvency risk
Investment 100
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 5
Price trend over the last 3–12 months (market factor)
52W Momentum 0
Distance to the 52-week high (market factor)
Net Issuance 57
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

All values are scores from 0 to 100 (100 = best against fixed, research-based bands), not percentages. The three market factors (momentum, 52-week proximity, low volatility) are displayed but carry zero weight in the headline number: market sentiment is not a business property.

About the company

Appili Therapeutics Inc., a biopharmaceutical company, focuses on the acquisition and development of novel medicines for unmet needs in infectious disease in Canada.

Full company description

Appili Therapeutics Inc., a biopharmaceutical company, focuses on the acquisition and development of novel medicines for unmet needs in infectious disease in Canada. Its anti-infective portfolio includes ATI-1501, a liquid oral taste-masked reformulation of the antibiotic metronidazole to treat anaerobic bacterial, protozoal, and parasitic infections; ATI-1801, a novel topical formulation of paromomycin for the treatment of cutaneous leishmaniasis; and ATI-1701, a live-attenuated vaccine for the treatment of francisella tularensis. The company was incorporated in 2015 and is headquartered in Halifax, Canada.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2022 – FY2026 · reported fiscal years

Appili Therapeutics Inc reported revenue of C$244K in FY2026 versus C$1.4M in FY2022, a compound −35.3%/yr. Reported net income was −C$4.2M in FY2026.

Growth Quality 9/100
Revenue growth is weak, negative or inconsistent.
Latest Revenue (FY 2026)
C$244K
Latest YoY
+143.1%
Avg. revenue growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
−9.9%
Avg. revenue growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+4.2%
Avg. revenue growth/yr (6Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+3.5%
EBIT margin (trend) Operating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−8,184.5% (2021) → −2,675.6% (2026)
Value creation/yr We only publish this rate when it is defensible. Reason: fiscal 2026 is a loss year, no rate is defined from a loss
not computed
Revenue −35.3%/yr
FY22 C$1.4M
FY23 C$334K
FY24 C$827K
FY25 C$100K
FY26 C$244K
Net income
FY22 −C$25.1M
FY23 −C$9.2M
FY24 −C$3.8M
FY25 −C$2.6M
FY26 −C$4.2M

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Cite: Fair Value Calculator (2026). "Appili Therapeutics Inc Fair Value". https://www.fairvalue-calculator.com/stock/APLI.TO

Peer Group

Biotechnology · 627 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 31 · Bottom 25%
Fair Value upside +0% · Top 25%
Net margin (TTM) 0% · Above median
Revenue growth 6% · Above median

Valuation Multiples vs Biotechnology median · lower = cheaper

P/S (TTM) 3.96× · Cheaper than median

Strength profile in five axes (Snowflake)

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE33 · sector 0
FUTURE31 · sector 0
PAST0 · sector 0
HEALTH100 · sector 98
DIVIDEND0 · sector 26

PAST 0: with negative equity (buybacks among others) return on equity is not meaningfully computable.

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jun 26, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $547.55 $278.78 −49%
Regeneron Pharmaceuticals, Inc REGN $807.71 $594.40 −26%
argenx SE ARGX €877.60 €292.84 −67%
BeOne Medicines AG 688235 ¥271.00 ¥47.36 −83%
Samsung Biologics Co 207940 1,518,000 KRW 1,055,793 KRW −30%
Alnylam Pharmaceuticals, Inc ALNY $228.61 $51.70 −77%
Royalty Pharma plc RPRX $60.58 $24.22 −60%
Celltrion, Inc 068270 190,700 KRW 74,519 KRW −61%
BioNTech SE BNTX $103.76 $45.70 −56%
Incyte Corporation INCY $123.22 $115.79 −6%

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Frequently asked questions

Is Appili Therapeutics Inc (APLI) overvalued or undervalued?
As of Jun 26, 2026, our model estimates a fair value of C$0.0143 versus a price of C$0.0100, about +43% upside (undervalued).
What is the fair value of APLI?
Our model-based fair value for Appili Therapeutics Inc is C$0.0143 (as of Jun 26, 2026), built from audited fundamentals. The current price: C$0.0100.
What is the quality score of APLI?
Appili Therapeutics Inc has a Quality Score of 31/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Appili Therapeutics Inc (APLI)?
Our model-based price target is the fair value of C$0.0143 (as of Jun 26, 2026) from 6 valuation models. It is a calculation from audited fundamentals, not an analyst target.
What is the Appili Therapeutics Inc stock forecast for 2026?
Our models put fair value at C$0.0143, about +43% upside versus a price of C$0.0100 (undervalued). The calculation is refreshed regularly with new filings.
What is the revenue of Appili Therapeutics Inc (APLI)?
Appili Therapeutics Inc reported trailing-twelve-month revenue of about C$206K (latest available figure, as of Jun 26, 2026).
What is the net profit margin of APLI?
The net profit margin of Appili Therapeutics Inc is about 0.0%, meaning it keeps roughly 0.0% of revenue as net income. Based on the latest reported figures.
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