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Assembly Biosciences Inc (ASMB) fair value: what the stock is really worth

As of Sep 23, 2026: fair value of Assembly Biosciences Inc $8.74, price $23.97, upside -63.6%, quality 40 out of 100. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.

  1. Fair value above price? No
  2. Good quality? No
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Healthcare · US · ISIN US0453962070

AB Assembly Biosciences Inc logo Thin data Sep 23, 2026

Assembly Biosciences Inc

ASMB · US

Weakest SetupStrongly overvalued and low quality.

!Fair value $8.74 · Strongly overvalued (−64%)
!Quality 40/100
!Weak Growth (revenue 5y −1.8 %/yr)
!Loss-making · -9.0% net margin (TTM)
!Low debt · negative free cash flow
!Trails peers (4/11)
!Narrow moat 15/100
!Evidence only low, so the estimate is less certain
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What runs behind every stock

26 valuation models 8 families, DCF to NCAV 37 quality factors margins, balance sheet, cashflow, debt 6 AI factors moat, what no ratio measures 2,000+ data points verified, per stock, median

69 individual criteria per stock, every one traceable See the method →

Price vs Fair Value

$49.20 $7.77 Fair Value $8.74 Jun 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 23, 2026.

How to read this chart

60‑month range $7.77 – $49.20 · fair‑value band $5.76 – $10.92 · the $23.97 price screens above the $8.74 fair value. Dashed = 300-day average. As of Sep 23, 2026.

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Company profile

Assembly Biosciences, Inc., a biotechnology company, develops therapeutic candidates for the treatment of viral diseases worldwide.

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Assembly Biosciences, Inc., a biotechnology company, develops therapeutic candidates for the treatment of viral diseases worldwide. Its pipeline includes long-acting helicase-primase inhibitors candidates, including ABI-5366 and ABI-1179, which are in Phase 1 clinical studies for recurrent genital herpes; and ABI-6250, an orally bioavailable hepatitis delta virus entry inhibitor that is in Phase 1a clinical study for the treatment of chronic hepatitis delta virus (HDV) infection. The company also develops ABI-4334, an orally bioavailable next generation capsid assembly modulator that is in Phase 1b study clinical trial for the treatment of chronic hepatitis B virus (HBV) infection; and ABI-7272, an oral broad-spectrum NNPI for the treatment of transplant-associated herpesviruses. It has an option, license, and collaboration agreement with Gilead Sciences, Inc. for the research and development of virology therapies. The company was formerly known as Ventrus Biosciences, Inc. and changed its name to Assembly Biosciences, Inc. in June 2014. Assembly Biosciences, Inc. was incorporated in 2005 and is headquartered in South San Francisco, California.

Stock analysis

Assembly Biosciences Inc (ASMB) currently trades at $23.97, while our model-based Fair Value estimate is $8.74, implying the stock looks roughly 174.3% overvalued today.

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Valuation

How firm this estimate is: it rests on 1 models at a data quality of 95/100, which puts the evidence level at low.

Scenario range: $5.76 (bear) to $10.92 (bull), the price of $23.97 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 40/100 (below-average quality), in the Healthcare sector.

Weak Growth: Revenue growth is weak: less than 2 % a year.

Assembly Biosciences Inc reported revenue of $72.3M in FY2025 versus $6.3M in FY2021, a compound +84.4%/yr. Reported net income was −$6.1M in FY2025.

Key figures

Market cap $500M · P/E ratio 299.6 · P/S ratio 7.03 · EPS (TTM) $0.0800 · Net margin −8.5% · Return on equity −5.7% · Return on assets (EBIT) −50.4% · Operating margin −138%.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 48 out of 100 (low confidence).

What moves the price

The share trades about 38% below its 52-week high and 8% above its 52-week low, currently below its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at −5% fair-value upside, at −64%, ASMB screens richer than that median.

Fair Value models

Bear $5.76 Fair Value $8.74 Bull $10.92
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above is their evidence-weighted blend, not the output of a single model. Based on fiscal year 2025 figures (about 9 months old). Earnings retained since then ($0.0585 per share) are deliberately not added. Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence ⓘEvidence = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
Highest evidence
NCAV (Graham) $5.22 $6.99 $10.43 54
All 1 models by family
Asset-Based
NCAV (Graham) $5.22 $6.99 $10.43 54

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Quality Score breakdown

Overall quality 40/100

Of which business quality 44 · Market factors (momentum, volatility) 32

Profitability 16
Margins and returns on capital today
Quality Growth 94
Are margins and returns improving?
Cashflow 33
Earnings quality: real cash, not paper profit
Fin. Strength 87
Balance sheet, leverage, solvency risk
Investment 33
Disciplined investing over empire-building
Low Volatility 28
Calm price path (market factor)
Momentum 42
Price trend over the last 3–12 months (market factor)
52W Momentum 20
Distance to the 52-week high (market factor)
Net Issuance 0
Share count: buybacks or dilution?

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Revenue & earnings trend

Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card. 0/100
Revenue growth is weak: less than 2 % a year.
Revenue growth 1 year
+153.5%
Revenue growth 5 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
−1.8%
Start year 2020 (pandemic)
Revenue growth 8 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+29.7%
Profit margin (trend) ⓘOperating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−81.9% (2020) → −16.8% (2025)
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

ASMB screens 174% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 651 stocks

Beats the industry median on 2/9 measures
Overall it trails its industry peers.
Valuation
Quality Score 45 · Above median
Fair Value upside −64% · Below median
Profitability
Return on assets −5% · Above median
Net margin (TTM) −9% · Below median
Operating margin (TTM) −138% · Bottom 25%
Growth and dividend
Revenue growth −13% · Bottom 25%

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/E (TTM) 299.6× · Priciest 25%
P/B 2.42× · Pricier than median
P/S (TTM) 7.03× · Pricier than median

Strength profile in five axes (Snowflake)

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE (fair-value potential)0 · sector 0
FUTURE (revenue growth)0 · sector 0
PAST (return on equity)0 · sector 0
HEALTH (low debt)100 · sector 97
DIVIDEND (yield)0 · sector 23

VALUE 0: the price sits above our fair-value range.

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $514.99 $566.49 +10%
Regeneron Pharmaceuticals, Inc REGN $803.90 $1,252 +56%
argenx SE ARGX $963.79 $918.60 −5%
Samsung Biologics Co 207940 1,366,000 KRW 1,502,600 KRW +10%
CSL Limited CSL A$179.24 A$197.16 +10%
Alnylam Pharmaceuticals, Inc ALNY $251.65 $218.36 −13%
Royalty Pharma plc RPRX $58.52 $24.22 −59%
BeOne Medicines AG 6160 HK$218.20 HK$169.72 −22%
Celltrion, Inc 068270 177,400 KRW 74,519 KRW −58%
BioNTech SE BNTX $100.87 $63.62 −37%

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Assembly Biosciences Inc · Fair Value
$8.74 −174%Fair Value
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Cite: Fair Value Calculator (2026). "Assembly Biosciences Inc Fair Value". https://www.fairvalue-calculator.com/stock/ASMB

Frequently asked questions

Is Assembly Biosciences Inc (ASMB) overvalued or undervalued?
As of Sep 23, 2026, our model estimates a fair value of $8.74 versus a price of $23.97, about −64% upside (overvalued).
What is the fair value of ASMB?
Our model-based fair value for Assembly Biosciences Inc is $8.74 (as of Sep 23, 2026), built from audited fundamentals. The current price: $23.97.
What is the quality score of ASMB?
Assembly Biosciences Inc has a Quality Score of 40/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Assembly Biosciences Inc (ASMB)?
Our model-based price target is the fair value of $8.74 (as of Sep 23, 2026) from 1 valuation models. Cautious scenario $5.76, optimistic scenario $10.92. It is a calculation from audited fundamentals, not an analyst target.
What is the Assembly Biosciences Inc stock forecast for 2026?
Our models put fair value at $8.74, about −64% upside versus a price of $23.97 (overvalued). Cautious scenario $5.76, optimistic scenario $10.92. The calculation is refreshed regularly with new filings.
What is the revenue of Assembly Biosciences Inc (ASMB)?
Assembly Biosciences Inc reported trailing-twelve-month revenue of about $71.1M (latest available figure, as of Sep 23, 2026).
What is the intrinsic value of Assembly Biosciences Inc (ASMB)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Assembly Biosciences Inc it is $8.74 per share (as of Sep 23, 2026), against a price of $23.97. It is the blended result of 1 valuation models (cash flow, earnings, asset, dividend).
Is Assembly Biosciences Inc stock overvalued or undervalued in 2026?
As of Sep 23, 2026, ASMB trades above its calculated fair value: price $23.97, fair value $8.74, a gap of about −64% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of ASMB?
No. The price is what the market pays today ($23.97); the fair value is what the company's own numbers justify ($8.74). For Assembly Biosciences Inc the two are $15.23 per share apart. That gap is exactly why we show both numbers side by side.
How much is Assembly Biosciences Inc worth?
The market values Assembly Biosciences Inc at about $500M (market capitalisation, as of Sep 23, 2026). Per share that is $23.97; our models calculate a fair value of $8.74 per share.
What do the bullish and bearish scenarios say about ASMB?
Our models span a range for Assembly Biosciences Inc: cautious scenario $5.76, base $8.74, optimistic $10.92 per share (as of Sep 23, 2026, price $23.97). The range comes from different growth and margin assumptions, not from analyst opinions.
What is the P/E ratio of ASMB?
Assembly Biosciences Inc trades at a price-to-earnings ratio of 299.6 (as of Sep 23, 2026). A P/E on its own says little: it compares the price with ONE year of profit, while our fair value of $8.74 is built from several models across several years. Other multiples: P/B 2.4, P/S 7.0.
How solid is the balance sheet of Assembly Biosciences Inc (ASMB)?
Balance-sheet figures for Assembly Biosciences Inc (as of Sep 23, 2026): return on equity −5.7%. They feed the Quality Score of 40/100, which measures business quality independently of the share price.
How far is ASMB from its 52-week high?
Assembly Biosciences Inc trades at $23.97, about 38% below its 52-week high of $38.50 and 8% above the low of $22.26 (as of Sep 23, 2026). Distance from the high says nothing about value: that is what the fair value of $8.74 is for.
Which stocks are comparable to Assembly Biosciences Inc?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, Samsung Biologics Co, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Assembly Biosciences Inc stock attractive at the current price?
The data as of Sep 23, 2026: price $23.97, calculated fair value $8.74 (−64%), Quality Score 40/100, from 1 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of ASMB calculated?
We run Assembly Biosciences Inc through 1 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of $8.74, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.1 % above its aggregate fair value. Assembly Biosciences Inc itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Assembly Biosciences Inc (ASMB)?
The closing price on Sep 23, 2026 was $23.97. Our model-based fair value is $8.74, about −64% upside (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Assembly Biosciences Inc right now?
The price sits above even our optimistic bull case ($10.92). The favourable scenario is already priced in. Weak quality (40/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution. A fairly wide model range ($5.76 to $10.92) leaves room in how you read the outcome.

Key figures of Assembly Biosciences Inc

How large is the market capitalisation of Assembly Biosciences Inc (ASMB)?
The market capitalisation of Assembly Biosciences Inc is $500M. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What is the P/S ratio of Assembly Biosciences Inc (ASMB)?
The price-to-sales ratio of Assembly Biosciences Inc is 7.03 (last twelve months). Price to sales: market value relative to yearly revenue. Useful when profit is thin or distorted.
What are the earnings per share of Assembly Biosciences Inc (ASMB)?
Earnings per share at Assembly Biosciences Inc are $0.0800 (price ÷ EPS = P/E 299.6). Earnings per share over the last twelve months: total profit spread across every single share.
What is the net margin of Assembly Biosciences Inc (ASMB)?
The net margin of Assembly Biosciences Inc is −8.5% (fiscal year 2025). How much of every unit of revenue ends up as profit. 10% means 10 cents of profit per dollar of sales.
What is the return on equity of Assembly Biosciences Inc (ASMB)?
The return on equity (ROE) of Assembly Biosciences Inc is −5.7% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Assembly Biosciences Inc (ASMB)?
On an EBIT basis the return on assets of Assembly Biosciences Inc is −50.4% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
What is the operating margin of Assembly Biosciences Inc (ASMB)?
The operating margin of Assembly Biosciences Inc is −138% (last twelve months). Profit from the core business (before interest and taxes) relative to revenue.
How fast is revenue growing at Assembly Biosciences Inc (ASMB)?
Revenue at Assembly Biosciences Inc is growing −12.8% versus a year earlier. How much revenue grew versus a year earlier (YoY). The 3-year average next to it puts the single year in context.
How much free cash flow does Assembly Biosciences Inc (ASMB) generate?
The free cash flow of Assembly Biosciences Inc is −$41.2M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net cash does Assembly Biosciences Inc (ASMB) hold?
Assembly Biosciences Inc holds more cash than debt, $55.8M net (fiscal year 2025). The company holds more cash than debt, a safety cushion.
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