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enGene Therapeutics Inc (ENGN) Fair Value & Analysis

Healthcare · US · Market cap $115M

ET enGene Therapeutics Inc logo enGene Therapeutics Inc ENGN · US
Price$1.80
Fair Value$1.87
Upside+3.9%
Quality19/100
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Thin margins · 0.0% net margin
Low debt · negative free cash flow
Mixed vs. peers (5/9)
Narrow moat 6/100
Evidence: Low Range $1.23 – $2.34 Share as image

Fair value as of: Jul 24, 2026

From 1 valuation models · updated 17 days ago

Share price −3.2% over the past month.

Below-average quality, currently priced close to our fair value.

What matters now

  • The price sits close to our fair value, market and models broadly agree here, little valuation tension.
  • A fairly wide model range ($1.23 to $2.34) leaves room in how you read the outcome.
  • Evidence is limited here (fewer models, shorter history), so the fair value is a rougher estimate than usual.
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Price vs Fair Value (5 years)

$28.44 $1.44 Fair Value $1.87 Feb 2022 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 24, 2026.

How to read this chart

54‑month range $1.44 – $28.44 · fair‑value band $1.23 – $2.34 · the $1.80 price screens below the $1.87 fair value. Dashed = 300-day average. As of Jul 24, 2026.

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Analysis

enGene Therapeutics Inc (ENGN) currently trades at $1.80, while our model-based Fair Value estimate is $1.87, implying the stock looks roughly 3.9% fairly valued today. The Quality Score stands at 19/100 (below-average quality), in the Healthcare sector. Bull case: trading below our estimate, it may offer upside if the fundamentals hold. Bear case: a low price can be a value trap when quality is weak or the data is thin (evidence: low), always confirm before acting.

It earns a return on equity of -52.6%. The balance sheet holds a net cash position of $18.4M. Fundamentals as of Jul 24, 2026

Our scenario range runs from $1.23 (bear case) to $2.34 (bull case); at $1.80, the current price sits within that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at 4%, ENGN screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
NCAV (Graham) $1.25 $1.68 $2.50 50
All 1 models by family
Asset-Based
NCAV (Graham) $1.25 $1.68 $2.50 50

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Key figures & financial health

Return on equity -52.6%
Free cash flow −$101M FY2025
EPS (TTM) $-2.18
Net cash $18.4M FY2025

Figures from reported company fundamentals · as of Jul 24, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 19/100

Of which business quality 25 · Market factors (momentum, volatility) 15

Profitability 0
Margins and returns on capital today
Quality Growth 25
Are margins and returns improving?
Cashflow 23
Earnings quality: real cash, not paper profit
Fin. Strength 67
Balance sheet, leverage, solvency risk
Investment 29
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 0
Price trend over the last 3–12 months (market factor)
52W Momentum 2
Distance to the 52-week high (market factor)
Net Issuance 0
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

enGene Therapeutics Inc., through its subsidiary enGene, Inc., operates as a clinical-stage biotechnology company in Canada. The company develops genetic medicines to help patients suffering from bladder cancer. Its lead product candidate is detalimogene voraplasmid, a monotherapy for the treatment of non-muscle invasive bladder cancer (NMIBC).

Full company description

enGene Therapeutics Inc., through its subsidiary enGene, Inc., operates as a clinical-stage biotechnology company in Canada. The company develops genetic medicines to help patients suffering from bladder cancer. Its lead product candidate is detalimogene voraplasmid, a monotherapy for the treatment of non-muscle invasive bladder cancer (NMIBC). Its pipeline includes LEGEND, which is in Phase 2. The company was formerly known as enGene Holdings Inc. and changed its name to enGene Therapeutics Inc. in April 2026. enGene Therapeutics Inc. is based in Montreal, Canada.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

enGene Therapeutics Inc reported revenue of $0 in FY2025 versus $0 in FY2021. Reported net income was −$117M in FY2025.

Revenue
FY21 $0
FY22 $0
FY23 $0
FY24 $0
FY25 $0
Net income
FY21 −$23.4M
FY22 −$24.5M
FY23 −$99.9M
FY24 −$55.1M
FY25 −$117M

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Cite: Fair Value Calculator (2026). "enGene Therapeutics Inc Fair Value". https://www.fairvalue-calculator.com/stock/ENGN

Peer Group

Biotechnology · 601 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 25 · Bottom 25%
Fair Value upside +4% · Top 25%
Return on assets -29% · Bottom 25%
Net margin (TTM) 0% · Above median
Operating margin (TTM) 0% · Above median
Revenue growth 0% · Above median
Debt / equity 0.09× · Higher than median

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 0.69× · Cheaper than median

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 39 · sector 0
FUTURE 0 · sector 0
PAST 0 · sector 0
HEALTH 95 · sector 98
DIVIDEND 0 · sector 23

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 24, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is enGene Therapeutics Inc (ENGN) overvalued or undervalued?
As of Jul 24, 2026, our model estimates a fair value of $1.87 versus a price of $1.80, about +4% (fairly valued).
What is the fair value of ENGN?
Our model-based fair value for enGene Therapeutics Inc is $1.87 (as of Jul 24, 2026), built from audited fundamentals. The current price is $1.80.
What is the quality score of ENGN?
enGene Therapeutics Inc has a Quality Score of 19/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the net profit margin of ENGN?
The net profit margin of enGene Therapeutics Inc is about 0.0%, meaning it keeps roughly 0.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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