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enGene Holdings Inc. (ENGN) fair value: what the stock is really worth

As of Sep 24, 2026: fair value of enGene Holdings Inc. $1.87, price $1.92, upside -2.6%, quality 19 out of 100. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.

  1. Fair value above price? No
  2. Good quality? No
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Healthcare · US · Home Canada · ISIN CA29286X1015

EH enGene Holdings Inc. logo Thin data Sep 24, 2026

enGene Holdings Inc.

ENGN · US

Low PriorityFair Value upside is limited and quality is weak.

·Fair value $1.87 · Fairly valued (−3%)
!Quality 19/100
!Low debt · negative free cash flow
!Mixed vs. peers (4/8)
!Narrow moat 6/100
!Evidence only low, so the estimate is less certain
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Price vs Fair Value

$28.44 $1.44 Fair Value $1.87 Feb 2022 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 24, 2026.

How to read this chart

56‑month range $1.44 – $28.44 · fair‑value band $1.23 – $2.34 · the $1.92 price screens above the $1.87 fair value. Dashed = 300-day average. As of Sep 24, 2026.

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Company profile

enGene Therapeutics Inc., through its subsidiary enGene, Inc., operates as a clinical-stage biotechnology company in Canada. The company develops genetic medicines to help patients suffering from bladder cancer. Its lead product candidate is detalimogene voraplasmid, a monotherapy for the treatment of non-muscle invasive bladder cancer (NMIBC).

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enGene Therapeutics Inc., through its subsidiary enGene, Inc., operates as a clinical-stage biotechnology company in Canada. The company develops genetic medicines to help patients suffering from bladder cancer. Its lead product candidate is detalimogene voraplasmid, a monotherapy for the treatment of non-muscle invasive bladder cancer (NMIBC). Its pipeline includes LEGEND, which is in Phase 2. The company was formerly known as enGene Holdings Inc. and changed its name to enGene Therapeutics Inc. in April 2026. enGene Therapeutics Inc. is based in Montreal, Canada.

Stock analysis

enGene Holdings Inc. Common Stock (ENGN) currently trades at $1.92, while our model-based Fair Value estimate is $1.87, implying the stock looks roughly 2.7% fairly valued today.

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Valuation

How firm this estimate is: it rests on 1 models at a data quality of 96/100, which puts the evidence level at low.

Scenario range: $1.23 (bear) to $2.34 (bull), the price of $1.92 sits inside it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 19/100 (below-average quality), in the Healthcare sector.

enGene Holdings Inc. Common Stock reported revenue of $0 in FY2025 versus $0 in FY2021. Reported net income was −$117M in FY2025.

Key figures

Market cap $134M · EPS (TTM) $−2.07 · Return on equity −60.5% · Return on assets (EBIT) −26.5% · Free cash flow −$101M · Net cash $18.4M.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 28 out of 100 (low confidence).

What moves the price

The share trades about 84% below its 52-week high and 33% above its 52-week low, currently below its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at −5% fair-value upside, at −3%, ENGN screens cheaper than that median.

Fair Value models

Bear $1.23 Fair Value $1.87 Bull $2.34
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above is their evidence-weighted blend, not the output of a single model. Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence ⓘEvidence = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
Highest evidence
NCAV (Graham) $1.25 $1.68 $2.50 54
All 1 models by family
Asset-Based
NCAV (Graham) $1.25 $1.68 $2.50 54

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Quality Score breakdown

Overall quality 19/100

Of which business quality 25 · Market factors (momentum, volatility) 24

Profitability 0
Margins and returns on capital today
Quality Growth 25
Are margins and returns improving?
Cashflow 23
Earnings quality: real cash, not paper profit
Fin. Strength 67
Balance sheet, leverage, solvency risk
Investment 29
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 20
Price trend over the last 3–12 months (market factor)
52W Momentum 2
Distance to the 52-week high (market factor)
Net Issuance 0
Share count: buybacks or dilution?

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Revenue & earnings trend

What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

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Earlier news

News mood ⓘNews mood, the average tone of recent news (31 articles), rated against how stocks are usually covered. 🚀 Hype = unusually upbeat · 🙂 Positive = above average · 😐 Neutral = typical · 🙁 Negative = below average · 😨 Very negative = unusually downbeat. It reflects the tone of coverage, not our valuation. Neutral
Recent news coverage is roughly neutral, about typical for how stocks are covered.

Compare enGene Holdings Inc. Common Stock with another stock

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 654 stocks

Beats the industry median on 4/7 measures
A mixed picture versus its industry peers.
Valuation
Quality Score 25 · Bottom 25%
Fair Value upside −7% · Above median
Profitability
Return on assets −32% · Bottom 25%
Operating margin (TTM) 0% · Above median
Growth and dividend
Revenue growth 0% · Above median
Balance sheet
Debt / equity 0.09× · Above median

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/B 0.83× · Cheaper than median

Strength profile in five axes (Snowflake)

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE (fair-value potential)30 · sector 0
FUTURE (revenue growth)0 · sector 0
PAST (return on equity)0 · sector 0
HEALTH (low debt)95 · sector 97
DIVIDEND (yield)0 · sector 23

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $522.38 $574.62 +10%
Regeneron Pharmaceuticals, Inc REGN $801.82 $1,252 +56%
argenx SE ARGX $963.79 $918.60 −5%
Samsung Biologics Co 207940 1,366,000 KRW 1,502,600 KRW +10%
CSL Limited CSL A$179.12 A$197.03 +10%
Alnylam Pharmaceuticals, Inc ALNY $251.65 $218.36 −13%
Royalty Pharma plc RPRX $58.52 $24.22 −59%
BeOne Medicines AG 6160 HK$218.20 HK$169.72 −22%
Celltrion, Inc 068270 177,400 KRW 74,519 KRW −58%
BioNTech SE BNTX $100.87 $63.62 −37%

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Cite: Fair Value Calculator (2026). "enGene Holdings Inc. Common Stock Fair Value". https://www.fairvalue-calculator.com/stock/ENGN

Frequently asked questions

Is enGene Holdings Inc. (ENGN) overvalued or undervalued?
As of Sep 24, 2026, our model estimates a fair value of $1.87 versus a price of $1.92, about −3% upside (fairly valued).
What is the fair value of ENGN?
Our model-based fair value for enGene Holdings Inc. Common Stock is $1.87 (as of Sep 24, 2026), built from audited fundamentals. The current price: $1.92.
What is the quality score of ENGN?
enGene Holdings Inc. Common Stock has a Quality Score of 19/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for enGene Holdings Inc. (ENGN)?
Our model-based price target is the fair value of $1.87 (as of Sep 24, 2026) from 1 valuation models. Cautious scenario $1.23, optimistic scenario $2.34. It is a calculation from audited fundamentals, not an analyst target.
What is the enGene Holdings Inc. Common Stock stock forecast for 2026?
Our models put fair value at $1.87, about −3% upside versus a price of $1.92 (fairly valued). Cautious scenario $1.23, optimistic scenario $2.34. The calculation is refreshed regularly with new filings.
What is the intrinsic value of enGene Holdings Inc. (ENGN)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For enGene Holdings Inc. Common Stock it is $1.87 per share (as of Sep 24, 2026), against a price of $1.92. It is the blended result of 1 valuation models (cash flow, earnings, asset, dividend).
Is enGene Holdings Inc. Common Stock stock overvalued or undervalued in 2026?
As of Sep 24, 2026, ENGN trades above its calculated fair value: price $1.92, fair value $1.87, a gap of about −3% (fairly valued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of ENGN?
No. The price is what the market pays today ($1.92); the fair value is what the company's own numbers justify ($1.87). For enGene Holdings Inc. Common Stock the two are $0.0500 per share apart. That gap is exactly why we show both numbers side by side.
How much is enGene Holdings Inc. Common Stock worth?
The market values enGene Holdings Inc. Common Stock at about $134M (market capitalisation, as of Sep 24, 2026). Per share that is $1.92; our models calculate a fair value of $1.87 per share.
What do the bullish and bearish scenarios say about ENGN?
Our models span a range for enGene Holdings Inc. Common Stock: cautious scenario $1.23, base $1.87, optimistic $2.34 per share (as of Sep 24, 2026, price $1.92). The range comes from different growth and margin assumptions, not from analyst opinions.
How solid is the balance sheet of enGene Holdings Inc. (ENGN)?
Balance-sheet figures for enGene Holdings Inc. Common Stock (as of Sep 24, 2026): return on equity −60.5%, debt of 0.09 per unit of equity. They feed the Quality Score of 19/100, which measures business quality independently of the share price.
How far is ENGN from its 52-week high?
enGene Holdings Inc. Common Stock trades at $1.92, about 84% below its 52-week high of $12.17 and 33% above the low of $1.44 (as of Sep 24, 2026). Distance from the high says nothing about value: that is what the fair value of $1.87 is for.
Which stocks are comparable to enGene Holdings Inc. Common Stock?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, Samsung Biologics Co, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is enGene Holdings Inc. Common Stock stock attractive at the current price?
The data as of Sep 24, 2026: price $1.92, calculated fair value $1.87 (−3%), Quality Score 19/100, from 1 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of ENGN calculated?
We run enGene Holdings Inc. Common Stock through 1 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of $1.87, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.0 % above its aggregate fair value. enGene Holdings Inc. Common Stock itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of enGene Holdings Inc. (ENGN)?
The closing price on Sep 24, 2026 was $1.92. Our model-based fair value is $1.87, about −3% upside (fairly valued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with enGene Holdings Inc. Common Stock right now?
The price sits close to our fair value, market and models broadly agree here, little valuation tension. A fairly wide model range ($1.23 to $2.34) leaves room in how you read the outcome. Evidence is limited here (fewer models, shorter history), so the fair value is a rougher estimate than usual.

Key figures of enGene Holdings Inc. Common Stock

How large is the market capitalisation of enGene Holdings Inc. (ENGN)?
The market capitalisation of enGene Holdings Inc. Common Stock is $134M. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What are the earnings per share of enGene Holdings Inc. (ENGN)?
Earnings per share at enGene Holdings Inc. Common Stock are $−2.07. Earnings per share over the last twelve months: total profit spread across every single share.
What is the return on equity of enGene Holdings Inc. (ENGN)?
The return on equity (ROE) of enGene Holdings Inc. Common Stock is −60.5% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of enGene Holdings Inc. (ENGN)?
On an EBIT basis the return on assets of enGene Holdings Inc. Common Stock is −26.5% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
How much free cash flow does enGene Holdings Inc. (ENGN) generate?
The free cash flow of enGene Holdings Inc. Common Stock is −$101M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net cash does enGene Holdings Inc. (ENGN) hold?
enGene Holdings Inc. Common Stock holds more cash than debt, $18.4M net (fiscal year 2025). The company holds more cash than debt, a safety cushion.
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