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Lexeo Therapeutics, Inc. (LXEO) fair value: what the stock is really worth

As of Sep 24, 2026: fair value of Lexeo Therapeutics, Inc. $1.73, price $3.39, upside -49.1%, quality 29 out of 100. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.

  1. Fair value above price? No
  2. Good quality? No
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Healthcare · US · ISIN US52886X1072

LT Lexeo Therapeutics, Inc. logo Thin data Sep 24, 2026

Lexeo Therapeutics, Inc.

LXEO · US

Weakest SetupStrongly overvalued and low quality.

!Fair value $1.73 · Strongly overvalued (−49%)
!Quality 29/100
!Weak Growth (revenue YoY −60.5 %/yr)
!negative free cash flow
!Mixed vs. peers (3/7)
!Narrow moat 8/100
!Evidence only low, so the estimate is less certain
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Price vs Fair Value

$18.76 $1.79 Fair Value $1.73 Nov 2023 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 24, 2026.

How to read this chart

35‑month range $1.79 – $18.76 · fair‑value band $1.14 – $2.15 · the $3.39 price screens above the $1.73 fair value. Dashed = 300-day average. As of Sep 24, 2026.

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Company profile

Lexeo Therapeutics, Inc., a clinical stage genetic medicine company, focuses on hereditary and acquired diseases with high unmet need in the United States.

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Lexeo Therapeutics, Inc., a clinical stage genetic medicine company, focuses on hereditary and acquired diseases with high unmet need in the United States. Its product pipeline comprises LX2006, an AAVrh10-based gene therapy candidate, which is in phase 1/2 clinical trial to treat friedreich ataxia cardiomyopathy; LX2020, an AAVrh10-based gene therapy candidate, which is in phase 1/2 to deliver a functional plakophilin-2 (PKP2) gene to cardiac muscle for the treatment of PKP2-ACM; and LX2021, a gene therapy candidate, which is in preclinical trial to deliver the coding sequence for the functional connexin 43, or Cx43, protein for a group of inherited cardiac muscle disorders associated with a high risk of sudden death, including arrhythmogenic cardiomyopathy (ACM) and certain forms of dilated cardiomyopathy. The company is also developing LX2022, a gene therapy candidate, which is in preclinical trial to deliver a functional TNNI3 gene to myocardial cells to treat a distinct form of hypertrophic cardiomyopathy. In addition, it is developing LX1001, LX1020, and LX1021, an AAVrh10-based gene therapy candidate, which has completed phase 1/2 clinical trial for the treatment of APOE4-associated Alzheimer's disease. The company has a license agreement with Cornell University to conduct the Phase 1/2 clinical trial of LX1001, as well as support the development of the LX1004 program; a research collaboration agreement with Cornell University to conduct preclinical research to develop the licensed technology; and third license agreement which obtained certain rights for FA cardiomyopathy, including rights to current and future clinical data from an ongoing Cornell University investigator-initiated Phase 1A trial of a gene therapy candidate. The company was founded in 2017 and is headquartered in New York, New York.

Stock analysis

Lexeo Therapeutics, Inc. Common Stock (LXEO) currently trades at $3.39, while our model-based Fair Value estimate is $1.73, implying the stock looks roughly 96.4% overvalued today.

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Valuation

How firm this estimate is: it rests on 1 models at a data quality of 96/100, which puts the evidence level at low.

Scenario range: $1.14 (bear) to $2.15 (bull), the price of $3.39 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 29/100 (below-average quality), in the Healthcare sector.

Weak Growth: Revenue growth is weak, negative or inconsistent.

Lexeo Therapeutics, Inc. Common Stock reported revenue of $0 in FY2025 versus $1.7M in FY2021. Reported net income was −$100.0M in FY2025.

Key figures

Market cap $341M · EPS (TTM) $−0.8800 · Return on equity −46.8% · Return on assets (EBIT) −52.2% · Free cash flow −$99.0M · Net cash $55.1M.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 32 out of 100 (low confidence).

What moves the price

The share trades about 68% below its 52-week high and at its 52-week low, currently below its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at −5% fair-value upside, at −49%, LXEO screens richer than that median.

Fair Value models

Bear $1.14 Fair Value $1.73 Bull $2.15
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above is their evidence-weighted blend, not the output of a single model. Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence ⓘEvidence = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
Highest evidence
NCAV (Graham) $1.50 $2.01 $3.01 51
All 1 models by family
Asset-Based
NCAV (Graham) $1.50 $2.01 $3.01 51

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Quality Score breakdown

Overall quality 29/100

Of which business quality 36 · Market factors (momentum, volatility) 10

Profitability 0
Margins and returns on capital today
Quality Growth 75
Are margins and returns improving?
Cashflow 32
Earnings quality: real cash, not paper profit
Fin. Strength 95
Balance sheet, leverage, solvency risk
Investment 0
Disciplined investing over empire-building
Low Volatility 11
Calm price path (market factor)
Momentum 15
Price trend over the last 3–12 months (market factor)
52W Momentum 0
Distance to the 52-week high (market factor)
Net Issuance 0
Share count: buybacks or dilution?

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Revenue & earnings trend

Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card. 0/100
Revenue growth is weak, negative or inconsistent.
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

LXEO screens 96% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

Earlier news

News mood ⓘNews mood, the average tone of recent news (40 articles), rated against how stocks are usually covered. 🚀 Hype = unusually upbeat · 🙂 Positive = above average · 😐 Neutral = typical · 🙁 Negative = below average · 😨 Very negative = unusually downbeat. It reflects the tone of coverage, not our valuation. Positive
Recent news coverage is more positive than average.

Compare Lexeo Therapeutics, Inc. Common Stock with another stock

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 654 stocks

Beats the industry median on 3/6 measures
A mixed picture versus its industry peers.
Valuation
Quality Score 36 · Below median
Fair Value upside −49% · Below median
Profitability
Return on assets −28% · Below median
Operating margin (TTM) 0% · Above median
Growth and dividend
Revenue growth 0% · Above median

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/B 1.38× · Cheaper than median

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $522.38 $574.62 +10%
Regeneron Pharmaceuticals, Inc REGN $801.82 $1,252 +56%
argenx SE ARGX $963.79 $918.60 −5%
Samsung Biologics Co 207940 1,366,000 KRW 1,502,600 KRW +10%
CSL Limited CSL A$179.12 A$197.03 +10%
Alnylam Pharmaceuticals, Inc ALNY $251.65 $218.36 −13%
Royalty Pharma plc RPRX $58.52 $24.22 −59%
BeOne Medicines AG 6160 HK$218.20 HK$169.72 −22%
Celltrion, Inc 068270 177,400 KRW 74,519 KRW −58%
BioNTech SE BNTX $100.87 $63.62 −37%

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Cite: Fair Value Calculator (2026). "Lexeo Therapeutics, Inc. Common Stock Fair Value". https://www.fairvalue-calculator.com/stock/LXEO

Frequently asked questions

Is Lexeo Therapeutics, Inc. (LXEO) overvalued or undervalued?
As of Sep 24, 2026, our model estimates a fair value of $1.73 versus a price of $3.39, about −49% upside (overvalued).
What is the fair value of LXEO?
Our model-based fair value for Lexeo Therapeutics, Inc. Common Stock is $1.73 (as of Sep 24, 2026), built from audited fundamentals. The current price: $3.39.
What is the quality score of LXEO?
Lexeo Therapeutics, Inc. Common Stock has a Quality Score of 29/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Lexeo Therapeutics, Inc. (LXEO)?
Our model-based price target is the fair value of $1.73 (as of Sep 24, 2026) from 1 valuation models. Cautious scenario $1.14, optimistic scenario $2.15. It is a calculation from audited fundamentals, not an analyst target.
What is the Lexeo Therapeutics, Inc. Common Stock stock forecast for 2026?
Our models put fair value at $1.73, about −49% upside versus a price of $3.39 (overvalued). Cautious scenario $1.14, optimistic scenario $2.15. The calculation is refreshed regularly with new filings.
What is the intrinsic value of Lexeo Therapeutics, Inc. (LXEO)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Lexeo Therapeutics, Inc. Common Stock it is $1.73 per share (as of Sep 24, 2026), against a price of $3.39. It is the blended result of 1 valuation models (cash flow, earnings, asset, dividend).
Is Lexeo Therapeutics, Inc. Common Stock stock overvalued or undervalued in 2026?
As of Sep 24, 2026, LXEO trades above its calculated fair value: price $3.39, fair value $1.73, a gap of about −49% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of LXEO?
No. The price is what the market pays today ($3.39); the fair value is what the company's own numbers justify ($1.73). For Lexeo Therapeutics, Inc. Common Stock the two are $1.66 per share apart. That gap is exactly why we show both numbers side by side.
How much is Lexeo Therapeutics, Inc. Common Stock worth?
The market values Lexeo Therapeutics, Inc. Common Stock at about $341M (market capitalisation, as of Sep 24, 2026). Per share that is $3.39; our models calculate a fair value of $1.73 per share.
What do the bullish and bearish scenarios say about LXEO?
Our models span a range for Lexeo Therapeutics, Inc. Common Stock: cautious scenario $1.14, base $1.73, optimistic $2.15 per share (as of Sep 24, 2026, price $3.39). The range comes from different growth and margin assumptions, not from analyst opinions.
How solid is the balance sheet of Lexeo Therapeutics, Inc. (LXEO)?
Balance-sheet figures for Lexeo Therapeutics, Inc. Common Stock (as of Sep 24, 2026): return on equity −46.8%. They feed the Quality Score of 29/100, which measures business quality independently of the share price.
How far is LXEO from its 52-week high?
Lexeo Therapeutics, Inc. Common Stock trades at $3.39, about 68% below its 52-week high of $10.63 and at the low of $3.39 (as of Sep 24, 2026). Distance from the high says nothing about value: that is what the fair value of $1.73 is for.
Which stocks are comparable to Lexeo Therapeutics, Inc. Common Stock?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, Samsung Biologics Co, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Lexeo Therapeutics, Inc. Common Stock stock attractive at the current price?
The data as of Sep 24, 2026: price $3.39, calculated fair value $1.73 (−49%), Quality Score 29/100, from 1 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of LXEO calculated?
We run Lexeo Therapeutics, Inc. Common Stock through 1 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of $1.73, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.0 % above its aggregate fair value. Lexeo Therapeutics, Inc. Common Stock itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Lexeo Therapeutics, Inc. (LXEO)?
The closing price on Sep 24, 2026 was $3.39. Our model-based fair value is $1.73, about −49% upside (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Lexeo Therapeutics, Inc. Common Stock right now?
The price sits above even our optimistic bull case ($2.15). The favourable scenario is already priced in. Weak quality (29/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution. A fairly wide model range ($1.14 to $2.15) leaves room in how you read the outcome.

Key figures of Lexeo Therapeutics, Inc. Common Stock

How large is the market capitalisation of Lexeo Therapeutics, Inc. (LXEO)?
The market capitalisation of Lexeo Therapeutics, Inc. Common Stock is $341M. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What are the earnings per share of Lexeo Therapeutics, Inc. (LXEO)?
Earnings per share at Lexeo Therapeutics, Inc. Common Stock are $−0.8800. Earnings per share over the last twelve months: total profit spread across every single share.
What is the return on equity of Lexeo Therapeutics, Inc. (LXEO)?
The return on equity (ROE) of Lexeo Therapeutics, Inc. Common Stock is −46.8% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Lexeo Therapeutics, Inc. (LXEO)?
On an EBIT basis the return on assets of Lexeo Therapeutics, Inc. Common Stock is −52.2% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
How much free cash flow does Lexeo Therapeutics, Inc. (LXEO) generate?
The free cash flow of Lexeo Therapeutics, Inc. Common Stock is −$99.0M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net cash does Lexeo Therapeutics, Inc. (LXEO) hold?
Lexeo Therapeutics, Inc. Common Stock holds more cash than debt, $55.1M net (fiscal year 2025). The company holds more cash than debt, a safety cushion.
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