Lexeo Therapeutics, Inc. (LXEO) fair value: what the stock is really worth
As of Nov 6, 2026: fair value (intrinsic value) of Lexeo Therapeutics, Inc. stock $1.73, price $2.89, that is 40.3% below the price, quality 36 out of 100. Rating: strongly overvalued. Calculated from audited financials with one of our 26 valuation models and 37 quality factors, updated daily.
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Lexeo Therapeutics, Inc.
LXEO · USOur calculation puts a fair price 40% below what the stock costs today.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 8, 2026.
How to read this chart
36‑month range $1.79 – $18.76 · fair‑value band $1.14 – $2.15 · the $2.89 price screens above the $1.73 fair value. As of Nov 8, 2026.
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Company profile
Lexeo Therapeutics, Inc., a clinical stage genetic medicine company, focuses on hereditary and acquired diseases with high unmet need in the United States.
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Its product pipeline comprises LX2006, an AAVrh10-based gene therapy candidate, which is in phase 1/2 clinical trial to treat friedreich ataxia cardiomyopathy; LX2020, an AAVrh10-based gene therapy candidate, which is in phase 1/2 to deliver a functional plakophilin-2 (PKP2) gene to cardiac muscle for the treatment of PKP2-ACM; and LX2021, a gene therapy candidate, which is in preclinical trial to deliver the coding sequence for the functional connexin 43, or Cx43, protein for a group of inherited cardiac muscle disorders associated with a high risk of sudden death, including arrhythmogenic cardiomyopathy (ACM) and certain forms of dilated cardiomyopathy.
The company is also developing LX2022, a gene therapy candidate, which is in preclinical trial to deliver a functional TNNI3 gene to myocardial cells to treat a distinct form of hypertrophic cardiomyopathy.
In addition, it is developing LX1001, LX1020, and LX1021, an AAVrh10-based gene therapy candidate, which has completed phase 1/2 clinical trial for the treatment of APOE4-associated Alzheimer's disease.
The company has a license agreement with Cornell University to conduct the Phase 1/2 clinical trial of LX1001, as well as support the development of the LX1004 program; a research collaboration agreement with Cornell University to conduct preclinical research to develop the licensed technology; and third license agreement which obtained certain rights for FA cardiomyopathy, including rights to current and future clinical data from an ongoing Cornell University investigator-initiated Phase 1A trial of a gene therapy candidate.
The company was founded in 2017 and is headquartered in New York, New York.
Stock analysis
Lexeo Therapeutics, Inc. (LXEO) currently trades at $2.89, while our model-based Fair Value estimate is $1.73, 40% below the price, so the stock looks overvalued today.
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Valuation
How firm this estimate is: it rests on 1 models at a data quality of 96/100, which puts the data coverage at low.
Scenario range: $1.14 (bear) to $2.15 (bull), the price of $2.89 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 36/100 (below-average quality), in the Healthcare sector.
Weak Growth: Revenue growth is weak, negative or inconsistent.
Lexeo Therapeutics, Inc. Common Stock reported revenue of $0 in FY2025 versus $1.7M in FY2021. Reported net income was −$100.0M in FY2025.
Key figures
Market cap $247M Micro · EPS (TTM) $−1.02 · Return on equity −46.8% · Return on assets (EBIT) −52.2% (5-year average) · Free cash flow −$99.0M · Net cash $55.1M.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 8 out of 100 (low confidence).
What moves the price
The share trades about 73% below its 52-week high and 10% above its 52-week low, currently below its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at 10% fair-value upside, at −40%, LXEO screens richer than that median.
Fair Value models
All 1 models by family
The fair value above starts from this blend and is adjusted for dilution from new shares.
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Insider trades
In the last 6 months, 4 officers or directors sold shares worth $323,329 and none bought.
- SaleRichard Nolan TownsendChief Executive Officer, Director6× since Nov 18, 2025: 98,934 shares, avg. $5.44$538,012Aug 18, 2026
- SaleJose Manuel OteroChief Operating Officer5× since Nov 18, 2025: 11,009 shares, avg. $5.45$59,959Aug 18, 2026
- SaleLouis Edward TamayoChief Financial Officer2× since Jul 1, 2026: 8,758 shares, avg. $4.69$41,053Aug 18, 2026
- SaleNarinder Pal BhallaChief Medical Officer22,306 shares at $4.42$98,593Jul 1, 2026
- SaleEric AdlerChief Medical Officer615 shares at $9.27$5,701Nov 18, 2025
- SaleJenny RobertsonChief Legal Officer549 shares at $9.27$5,089Nov 18, 2025
- SaleTai Sandi SeeChief Development Officer386 shares at $9.27$3,578Nov 18, 2025
Plus 7 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.
Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.
Source: SEC Form 4, as of Nov 6, 2026. All filings at the SEC ↗
Revenue & earnings trend
Compare Lexeo Therapeutics, Inc. Common Stock with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 558 stocks
Valuation Multiplesvs Biotechnology median · lower = cheaper
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
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Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Biotechnology stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| Incyte Corporation INCY | $119.65 | $199.23 | +67% | vs LXEO |
| Regeneron Pharmaceuticals, Inc REGN | $904.35 | $1,275 | +41% | vs LXEO |
| Vertex Pharmaceuticals Incorporated VRTX | $547.09 | $601.80 | +10% | vs LXEO |
| Samsung Biologics Co 207940 | 1,516,000 KRW | 1,667,600 KRW | +10% | vs LXEO |
| Genmab A/S GMAB | kr 3,527 | kr 3,880 | +10% | vs LXEO |
| WuXi Biologics (Cayman) Inc 2269 | HK$47.62 | HK$52.38 | +10% | vs LXEO |
| argenx SE ARGX | $927.21 | $908.40 | −2% | vs LXEO |
| CSL Limited CSL | A$200.77 | A$183.04 | −9% | vs LXEO |
| Celltrion, Inc 068270 | 211,000 KRW | 74,945 KRW | −64% | vs LXEO |
| Royalty Pharma plc RPRX | $67.30 | $19.01 | −72% | vs LXEO |
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Key figures of Lexeo Therapeutics, Inc.
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