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Lyell Immunopharma, Inc (LYEL) Fair Value & Analysis

Healthcare · US · Market cap $297M

Price$13.00
Fair Value$7.25
Upside-44.2%
Quality95/100
Evidence: Low Range $4.78 – $9.06

Fair value as of: Jun 25, 2026

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Analysis

Lyell Immunopharma, Inc (LYEL) currently trades at $13.00, while our model-based Fair Value estimate is $7.25 — implying the stock looks roughly 44.2% overvalued today. We read business quality at 95/100 (high quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium — the entry price still matters most (evidence: low).

About the company

Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The company's lead product candidate include rondecabtagene autoleucel, an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development, which is in pivotal PiNACLE trial in the 3L+ setting and in a Phase 1/2 clinical trial in the 2L setting, as well as a second pivotal trial, PiNACLE-H2H, which is a Phase 3 head-to-head CAR T cell therapy randomized controlled trial of ronde-cel for LBCL in the 2L setting for the treatment of large B-cell lymphoma; and LYL273, a GCC-targeted CAR T-cell product candidate enhanced with CD19 CAR expression and controlled cytokine release designed to improve CAR T-cell expansion, immune cell infiltration, and cancer cell killing in the hostile solid tumor microenvironment, which is in Phase 1 clinical trial for the treatment of refractory metastatic colo…

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Frequently asked questions

Is Lyell Immunopharma, Inc (LYEL) undervalued?
As of Jun 25, 2026, our model estimates a fair value of $7.25 versus a price of $13.00 — about −44% (overvalued). Model-based estimate, not financial advice.
What is the fair value of LYEL?
Our 21-model fair value for Lyell Immunopharma, Inc is $7.25 (as of Jun 25, 2026), built from audited fundamentals. The current price is $13.00.
What is the quality score of LYEL?
Lyell Immunopharma, Inc has a Quality Score of 95/100, measuring profitability, growth and balance-sheet strength from non-valuation factors.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data — nothing guessed.

Educational research only · not financial advice · no buy/sell recommendation. Model-based estimates are not certainties; their reliability depends on data quality and assumptions.