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Roche Holding AG (ROP) Fair Value & Analysis

Healthcare · CH · Market cap CHF 263B · ISIN CH1499059983

What is Roche Holding AG really worth?

RH Roche Holding AG ROP · SW
PriceCHF 357.00
Fair ValueCHF 357.30
Upside+0.1%
Quality76/100

A strong business, currently priced close to our fair value of CHF 357.30.

As of Sep 6, 2026, the fair value of Roche Holding AG is CHF 357.30 per share against a price of CHF 357.00, so the fair value sits 0% above the price. A model estimate blended from multiple valuation models, recalculated regularly.

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Strengths

Highly profitable · 20.3% net margin
Moderate debt · generates free cash flow
Ranks above peers (10/15)
Wide moat 87/100

Risks

!Weak Growth (revenue 5y +1.1 %/yr)
!Weak on valuation: 12 out of 100

For context

·2.75% dividend yield
Evidence: High Range CHF 226.97 – CHF 514.13

Fair value as of: Sep 6, 2026

From 25 valuation models · updated today

Share price −2.1% over the past month.

What runs behind every stock

69 individual criteria per stock, every one traceable See the method →

What matters now

  • The price sits close to our fair value, market and models broadly agree here, little valuation tension.
  • A fairly wide model range (CHF 226.97 to CHF 514.13) leaves room in how you read the outcome.

Price vs Fair Value (5 years)

CHF 375.60 CHF 201.09 Fair Value CHF 357.30 Jun 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 6, 2026.

How to read this chart

60‑month range CHF 201.09 – CHF 375.60 · fair‑value band CHF 226.97 – CHF 514.13 · the CHF 357.00 price screens below the CHF 357.30 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Sep 6, 2026.

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Analysis

Roche Holding AG (ROP) currently trades at CHF 357.00, while our model-based Fair Value estimate is CHF 357.30, implying the stock looks roughly 0.1% fairly valued today. The Quality Score stands at 76/100 (high quality), in the Healthcare sector. Bull case: the Growth Earnings group reads highest at a median of CHF 323.38 per share, and 5 of the 25 models we run sit above the CHF 357.00 price. Bear case: the Economic Profit group reads lowest at CHF 149.68, and 20 of the 25 models stay below the price. Evidence for this calculation is high.

Over the trailing twelve months, Roche Holding AG generated revenue of CHF 63.4B at a net margin of 20.3%. Revenue declined 0.4% year over year. It earns a return on equity of 37.3%. Net debt stands at CHF 27.6B. Fundamentals as of Sep 6, 2026

Our scenario range runs from CHF 226.97 (bear case) to CHF 514.13 (bull case); at CHF 357.00, the current price sits within that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 2% below its 52-week high and 51% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at −11% fair-value upside, at 0%, ROP screens cheaper than that median.

Fair Value models

This estimate rests on fiscal year 2025 figures, and about 8 months have passed since. In that time the company retained roughly CHF 4.25 per share, which is 1.2 % of the fair value. The fair value deliberately does not add this in: the models value reported figures, not a projection.

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted, family-balanced blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small. Every input is real reported data, nothing guessed.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
FCF DCF best evidence CHF 193.49 CHF 293.53 CHF 440.70 80
Growth DCF CHF 201.86 CHF 297.18 CHF 432.43 78
Owner Earnings CHF 168.48 CHF 257.41 CHF 388.23 76
All 25 models by family
DCF Models
FCF DCF best evidence CHF 193.49 CHF 293.53 CHF 440.70 80
Owner Earnings CHF 168.48 CHF 257.41 CHF 388.23 76
5Y Revenue Exit CHF 161.11 CHF 252.44 CHF 363.26 72
5Y EBITDA Exit CHF 242.46 CHF 394.99 CHF 563.35 75
5Y P/E Exit CHF 221.75 CHF 358.71 CHF 492.95 71
10Y Revenue Exit CHF 165.36 CHF 249.76 CHF 350.79 67
10Y EBITDA Exit CHF 222.61 CHF 347.58 CHF 497.99 68
10Y P/E Exit CHF 209.45 CHF 322.68 CHF 446.19 64
Earnings-Based
Graham-Dodd CHF 127.13 CHF 269.45 CHF 341.63 66
PEG = 1.0 CHF 40.83 CHF 58.33 CHF 75.83 57
EPV CHF 201.84 CHF 243.05 CHF 279.69 74
Dividend Discount
Gordon GGM CHF 117.07 CHF 182.43 CHF 256.16 68
DDM Multi-Stage CHF 117.07 CHF 170.78 CHF 234.66 66
Multiples
P/E Multiple CHF 308.48 CHF 411.31 CHF 514.13 63
P/S Multiple CHF 234.39 CHF 312.52 CHF 390.65 58
P/B Multiple CHF 165.59 CHF 220.79 CHF 275.99 55
EV/EBIT CHF 324.81 CHF 443.65 CHF 562.49 66
EV/EBITDA CHF 313.50 CHF 428.57 CHF 543.64 67
EV/Revenue CHF 155.80 CHF 236.16 CHF 316.53 53
Asset-Based
NCAV (Graham) CHF 24.53 CHF 32.87 CHF 49.06 54
Growth DCF
Growth DCF CHF 201.86 CHF 297.18 CHF 432.43 78
Rev-Margin DCF CHF 161.11 CHF 255.46 CHF 354.68 72
Economic Profit
Residual Income CHF 120.11 CHF 149.68 CHF 785.61 64
ROIC Compounder CHF 209.53 CHF 262.33 CHF 317.02 72
Growth Earnings
Growth-Adj P/E CHF 226.37 CHF 323.38 CHF 420.39 67

Widest divergence: Growth Earnings (CHF 323.38) versus Asset-Based (CHF 32.87). Highest evidence: FCF DCF (80).

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Key figures & financial health

P/E ratio 20.5 as of Jun 1, 2026
P/S ratio 4.30 P/E × margin
EPS (TTM) CHF 16.04 price ÷ EPS = P/E 20.5
Dividend yield 2.7% payout 61.1%
Net margin 20.9% FY2025
Return on equity 37.3% TTM
More key figures
Profitability
Return on assets (EBIT) 17.8% avg 5y
Operating margin 30.0% TTM
Growth
Revenue (TTM) CHF 63.4B TTM
Revenue growth (YoY) −0.4% 3y avg −2.2%
EPS growth (YoY) +171%
Balance sheet & cash flow
Free cash flow CHF 14.1B FY2025
Net debt CHF 27.6B FY2025 · ≈ 2.0 yrs of FCF

Figures from reported company fundamentals · as of Sep 6, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 76/100

Of which business quality 73 · Market factors (momentum, volatility) 77

Profitability 77
Margins and returns on capital today
Quality Growth 61
Are margins and returns improving?
Cashflow 81
Earnings quality: real cash, not paper profit
Fin. Strength 63
Balance sheet, leverage, solvency risk
Investment 74
Disciplined investing over empire-building
Low Volatility 90
Calm price path (market factor)
Momentum 63
Price trend over the last 3–12 months (market factor)
52W Momentum 87
Distance to the 52-week high (market factor)
Net Issuance 81
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

All values are scores from 0 to 100 (100 = best against fixed, research-based bands), not percentages. The three market factors (momentum, 52-week proximity, low volatility) are displayed but carry zero weight in the headline number: market sentiment is not a business property.

About the company

Roche Holding AG engages in the pharmaceuticals and diagnostics businesses in Europe, North America, Latin America, Asia, Africa, Australia, and New Zealand.

Full company description

Roche Holding AG engages in the pharmaceuticals and diagnostics businesses in Europe, North America, Latin America, Asia, Africa, Australia, and New Zealand. The company offers pharma solutions in the therapeutic areas of anaemia, blood and solid tumors, dermatology, haematology, infectious diseases, inflammatory and autoimmune, neurological disorders, ophthalmology, respiratory disorders, and transplantation. It also provides in vitro tests for the diagnosis of various diseases, such as cancer, diabetes, Covid-19, hepatitis, human papillomavirus, and others; diagnostic instruments; and digital health solutions. The company was founded in 1896 and is based in Basel, Switzerland.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Roche Holding AG reported revenue of CHF 61.5B in FY2025 versus CHF 62.8B in FY2021, a compound −0.5%/yr. Reported net income was CHF 12.9B in FY2025, compounding −1.9%/yr from FY2021.

Growth Quality 40/100
Revenue growth is weak, negative or inconsistent.
Latest Revenue (FY 2025)
CHF 61.5B
Latest YoY
−1.4%
Avg. revenue growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
−2.2%
Avg. revenue growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+1.1%
Avg. revenue growth/yr (27Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+3.4%
Value creation/yr (5Y) Earnings growth per share (CAGR 5 years) plus dividend yield: value created per share and year.
+2.5% · in CHF
Earnings growth per share plus dividend yield: the value created per share and year.
Earnings growth per share−0.2%
Dividend yield2.7%
Trend Two data points, not a trend model: earnings growth per share over the last 5 fiscal years against the last 10. Labelled "steady" when both rates are within 3 percentage points of each other, otherwise picking up or flattening. Shown only when ten years of history exist.5Y −0.2% vs 10Y 4.0%, flattening
Operating margin (EBIT) Operating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.30.4% (2020) → 31.3% (2025) · steady
Worst earnings drop34% (2024) · in CHF
Revenue −0.5%/yr
FY21 CHF 62.8B
FY22 CHF 65.8B
FY23 CHF 60.4B
FY24 CHF 62.4B
FY25 CHF 61.5B
Net income −1.9%/yr
FY21 CHF 13.9B
FY22 CHF 12.4B
FY23 CHF 11.5B
FY24 CHF 8.3B
FY25 CHF 12.9B
Character of growth · EPS growth decomposed (2014-2025) +2.6 % p.a.
Revenue per share +2.9 %

of which total revenue +2.1 % · buybacks/dilution +0.8 %

EBIT margin −2.2 %
Tax rate +0.9 %
Residual (interest, one-offs) +1.1 %

Annual growth per factor. These are factors, not summands: multiplied they give the EPS growth rate, added they do not quite. Start and end points are 3-year averages (details on hover).

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Cite: Fair Value Calculator (2026). "Roche Holding AG Fair Value". https://www.fairvalue-calculator.com/stock/ROP.SW

Recent news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Drug Manufacturers - General · 75 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 75 · Top 25%
Fair Value upside −16% · Above median
Return on equity (TTM) 37% · Top 25%
Return on assets 13% · Top 25%
Net margin (TTM) 20% · Above median
Operating margin (TTM) 30% · Above median
Revenue growth 0% · Below median
Dividend yield (TTM) 2.7% · Above median
Debt / equity 0.81× · Higher than 75% of peers

Valuation Multiples vs Drug Manufacturers - General median · lower = cheaper

P/E (TTM) 20.5× · Cheaper than median
P/B 9.60× · Pricier than 75% of peers
P/S (TTM) 5.12× · Pricier than median
P/FCF 23.0× · Pricier than median
EV/EBITDA 14.4× · Cheaper than median
PEG 1.43× · Cheaper than median

Strength profile in five axes (Snowflake)

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE12 · sector 0
FUTURE0 · sector 29
PAST100 · sector 49
HEALTH59 · sector 94
DIVIDEND55 · sector 42

Insider activity: 30/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Drug Manufacturers - General stocks, each showing price versus our Fair Value estimate (as of Sep 6, 2026).

Stock Price Fair Value vs Fair Value
Eli Lilly and Company LLY $1,176 $389.47 −67%
Johnson & Johnson, JNJ $275.23 $169.04 −39%
AbbVie Inc ABBV $256.46 $67.72 −74%
Merck & Co MRK €131.98 €101.38 −23%
Novartis AG NOVN CHF 123.74 CHF 114.90 −7%
Novo Nordisk A/S NOVOB kr 295.50 kr 409.46 +39%
Amgen Inc AMGN $437.23 $252.02 −42%
Gilead Sciences, Inc GILD $151.00 $146.50 −3%
Pfizer Inc PFE $28.02 $24.87 −11%
Bristol-Myers Squibb Company BMY $66.58 $75.98 +14%

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Frequently asked questions

Is Roche Holding AG (ROP) overvalued or undervalued?
As of Sep 6, 2026, our model estimates a fair value of CHF 357.30 versus a price of CHF 357.00, about +0% upside (fairly valued).
What is the fair value of ROP?
Our model-based fair value for Roche Holding AG is CHF 357.30 (as of Sep 6, 2026), built from audited fundamentals. The current price: CHF 357.00.
What is the quality score of ROP?
Roche Holding AG has a Quality Score of 76/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Roche Holding AG (ROP)?
Our model-based price target is the fair value of CHF 357.30 (as of Sep 6, 2026) from 25 valuation models. Cautious scenario CHF 226.97, optimistic scenario CHF 514.13. It is a calculation from audited fundamentals, not an analyst target.
What is the Roche Holding AG stock forecast for 2026?
Our models put fair value at CHF 357.30, about +0% upside versus a price of CHF 357.00 (fairly valued). Cautious scenario CHF 226.97, optimistic scenario CHF 514.13. The calculation is refreshed regularly with new filings.
What is the revenue of Roche Holding AG (ROP)?
Roche Holding AG reported trailing-twelve-month revenue of about CHF 63.4B (latest available figure, as of Sep 6, 2026).
What is the net profit margin of ROP?
The net profit margin of Roche Holding AG is about 20.3%, meaning it keeps roughly 20.3% of revenue as net income. Based on the latest reported figures.
Does Roche Holding AG pay a dividend?
Roche Holding AG currently shows a dividend yield of about 2.75% relative to its recent price (as of Sep 6, 2026).
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