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Sarepta Therapeutics, Inc (SRPT) Fair Value & Analysis

Healthcare · US · Market cap $1.8B

ST Sarepta Therapeutics, Inc logo Sarepta Therapeutics, Inc SRPT · US
Price$16.78
Fair Value$46.49
Upside+177.1%
Quality36/100
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Mixed Growth
Thin margins · 3.0% net margin
Moderate debt · negative free cash flow
Mixed vs. peers (6/13)
Moderate moat 49/100
Evidence: Low Range $23.56 – $69.69 Share as image

Fair value as of: Jul 17, 2026

From 3 valuation models · updated 24 days ago

Share price −17.0% over the past month.

Below-average quality, screening 177% undervalued on our models.

What matters now

  • The large discount to fair value meets weak quality (36/100). That raises the risk this is a value trap rather than a bargain.
  • The price is below even our cautious bear case ($23.56). The market is more pessimistic than our downside scenario.
  • The model range is unusually wide ($23.56 to $69.69). The outcome hinges heavily on assumptions, so read the point estimate with caution.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.
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Price vs Fair Value (5 years)

$163.85 $11.93 Fair Value $46.49 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 17, 2026.

How to read this chart

60‑month range $11.93 – $163.85 · fair‑value band $23.56 – $69.69 · the $16.78 price screens below the $46.49 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 17, 2026.

Full chart & analysis →

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Analysis

Sarepta Therapeutics, Inc (SRPT) currently trades at $16.78, while our model-based Fair Value estimate is $46.49, implying the stock looks roughly 177.1% undervalued today. The Quality Score stands at 36/100 (below-average quality), in the Healthcare sector. Bull case: trading below our estimate, it may offer upside if the fundamentals hold. Bear case: a low price can be a value trap when quality is weak or the data is thin (evidence: low), always confirm before acting.

Over the trailing twelve months, Sarepta Therapeutics, Inc generated revenue of $2.2B at a net margin of 3.0%. Revenue declined 1.9% year over year. It earns a return on equity of 4.9%. Net debt stands at $238M. Fundamentals as of Jul 17, 2026

Our scenario range runs from $23.56 (bear case) to $69.69 (bull case); at $16.78, the current price sits below that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The last reported earnings sit well below what analysts expect (earnings in transition, for example after write-downs or an earnings dip); whether the stock is cheap or expensive hinges on the expected recovery actually arriving. Read the fair value with that caveat. The share trades about 62% below its 52-week high and 61% above its 52-week low, currently below its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at 177%, SRPT screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Gordon GGM $21.07 $37.97 $52.27 70
DDM Multi-Stage $21.07 $34.68 $40.56 61
NCAV (Graham) $5.40 $7.24 $10.80 50
All 3 models by family
Dividend Discount
Gordon GGM $21.07 $37.97 $52.27 70
DDM Multi-Stage $21.07 $34.68 $40.56 61
Asset-Based
NCAV (Graham) $5.40 $7.24 $10.80 50

Widest divergence: Dividend Discount ($34.68) versus Asset-Based ($7.24). Highest evidence: Gordon GGM (70).

Key figures & financial health

Revenue (TTM) $2.2B
Revenue growth (YoY) -1.9%
Net margin 3.0%
Return on equity 4.9%
Free cash flow −$307M FY2025
P/E ratio 46.6
More key figures
Operating margin 49.1%
EPS (TTM) $0.3500
EPS growth (YoY) +2,664%
Net debt $238M FY2025

Figures from reported company fundamentals · as of Jul 17, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 36/100

Of which business quality 33 · Market factors (momentum, volatility) 37

Profitability 23
Margins and returns on capital today
Quality Growth 34
Are margins and returns improving?
Cashflow 0
Earnings quality: real cash, not paper profit
Fin. Strength 46
Balance sheet, leverage, solvency risk
Investment 58
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 29
Price trend over the last 3–12 months (market factor)
52W Momentum 37
Distance to the 52-week high (market factor)
Net Issuance 59
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, siRNA platform, gene therapy, and other genetic therapeutic modalities for the treatment of rare diseases.

Full company description

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, siRNA platform, gene therapy, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping; AMONDYS 45 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 45 skipping; and ELEVIDYS, an AAV-based gene therapy, which is contraindicated in patients with any deletion in exon 8 and/or exon 9 in the Duchenne gene. The company also develops SRP-9003, a gene therapy program for the treatment of LGMD2E; SRP-1001 to selectively target and knockdown DUX4 using RNAi in Phase 1/2a clinical trials; and SRP-1003 for reduction of expression of the DMPK gene in Phase 1/2a clinical trials. It has collaboration and license agreements with F. Hoffman-La Roche Ltd; Arrowhead Pharmaceuticals, Inc.; University of Western Australia; Nationwide Children's Hospital; Hansa Biopharma; and Duke University. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Sarepta Therapeutics, Inc reported revenue of $2.2B in FY2025 versus $702M in FY2021, a compound +33.0%/yr. Reported net income was −$713M in FY2025.

Growth Quality 50/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$2.2B
Latest YoY
+15.6%
Avg. growth/yr (3Y)
+33.1%
Avg. growth/yr (5Y)
+32.4%
Avg. growth/yr (30Y)
+39.6%
Revenue +33.0%/yr
FY21 $702M
FY22 $933M
FY23 $1.2B
FY24 $1.9B
FY25 $2.2B
Net income
FY21 −$419M
FY22 −$703M
FY23 −$536M
FY24 $235M
FY25 −$713M

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Cite: Fair Value Calculator (2026). "Sarepta Therapeutics, Inc Fair Value". https://www.fairvalue-calculator.com/stock/SRPT

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 36 · Below median
Fair Value upside +177% · Top 25%
Return on equity (TTM) 5% · Above median
Return on assets 0% · Above median
Net margin (TTM) 3% · Above median
Operating margin (TTM) 49% · Top 25%
Revenue growth -2% · Below median
Debt / equity 0.73× · Higher than 75% of peers

Valuation Multiples vs Biotechnology median · lower = cheaper

P/E (TTM) 50.7× · Pricier than 75% of peers
P/B 1.59× · Pricier than median
P/S (TTM) 0.83× · Cheaper than 75% of peers
EV/EBITDA 40.0× · Pricier than 75% of peers
PEG 159.25× · Pricier than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 100 · sector 0
FUTURE 0 · sector 0
PAST 20 · sector 0
HEALTH 64 · sector 97
DIVIDEND 0 · sector 23

Insider activity: 46/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 17, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is Sarepta Therapeutics, Inc (SRPT) overvalued or undervalued?
As of Jul 17, 2026, our model estimates a fair value of $46.49 versus a price of $16.78, about +177% (undervalued).
What is the fair value of SRPT?
Our model-based fair value for Sarepta Therapeutics, Inc is $46.49 (as of Jul 17, 2026), built from audited fundamentals. The current price is $16.78.
What is the quality score of SRPT?
Sarepta Therapeutics, Inc has a Quality Score of 36/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Sarepta Therapeutics, Inc (SRPT)?
Sarepta Therapeutics, Inc reported trailing-twelve-month revenue of about $2.2B (latest available figure, as of Jul 17, 2026).
What is the net profit margin of SRPT?
The net profit margin of Sarepta Therapeutics, Inc is about 3.0%, meaning it keeps roughly 3.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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