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TG Therapeutics, Inc (TGTX) Fair Value & Analysis

Healthcare · US · Market cap $8.4B

TT TG Therapeutics, Inc logo TG Therapeutics, Inc TGTX · US
Price$49.76
Fair Value$36.86
Upside-25.9%
Quality53/100
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Mixed Growth
Highly profitable · 66.0% net margin
Low debt · negative free cash flow
Ranks above peers (8/13)
Wide moat 74/100
Evidence: High Range $20.10 – $85.56 Share as image

Fair value as of: Jul 19, 2026

From 15 valuation models · updated 21 days ago

Fair value updated Jul 19, 2026, revised from $36.12 to $36.86 (+2.0%) since Jul 18, 2026. Share price −13.1% over the past month.

A solid business, but screening 26% overvalued on our models.

What matters now

  • The model range is unusually wide ($20.10 to $85.56). The outcome hinges heavily on assumptions, so read the point estimate with caution.
  • Solid but not exceptional quality (53/100) and above fair value, neither a clear bargain nor a standout compounder.
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Price vs Fair Value (5 years)

$59.06 $3.74 Fair Value $36.86 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 19, 2026.

How to read this chart

60‑month range $3.74 – $59.06 · fair‑value band $20.10 – $85.56 · the $49.76 price screens above the $36.86 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 19, 2026.

Full chart & analysis →

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Analysis

TG Therapeutics, Inc (TGTX) currently trades at $49.76, while our model-based Fair Value estimate is $36.86, implying the stock looks roughly 25.9% overvalued today. The Quality Score stands at 53/100 (solid quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: high).

Over the trailing twelve months, TG Therapeutics, Inc generated revenue of $700M at a net margin of 66.0%. Revenue grew 69.6% year over year. It earns a return on equity of 112.6%. Net debt stands at $182M. Fundamentals as of Jul 19, 2026

Our scenario range runs from $20.10 (bear case) to $85.56 (bull case); at $49.76, the current price sits within that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. Analysts expect earnings well below the last reported figure (earnings in transition, for example expiring patents or contracts); a fair value that looks fair on trailing earnings may then be too optimistic. The share trades near its 52-week high and 97% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at -26%, TGTX screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Residual Income $25.14 $43.77 $1,145 76
ROIC Compounder $6.97 $10.14 $12.90 72
Growth-Adj P/E $95.00 $135.72 $176.43 68
All 15 models by family
DCF Models
Owner Earnings $42.27 $95.01 $201.65 31
Earnings-Based
Graham-Dodd $19.86 $138.53 $194.40 54
Lynch FV $71.57 $102.24 $132.91 50
PEG = 1.0 $71.57 $102.24 $132.91 46
EPV $5.50 $6.54 $7.44 59
Multiples
P/E Multiple $48.20 $64.27 $80.33 63
P/S Multiple $10.57 $14.09 $17.61 58
P/B Multiple $14.29 $19.05 $23.81 55
EV/EBIT $9.18 $12.61 $16.03 53
EV/EBITDA $7.38 $10.20 $13.02 54
EV/Revenue $6.24 $9.39 $12.53 43
Asset-Based
NCAV (Graham) $2.12 $2.84 $4.23 50
Economic Profit
Residual Income $25.14 $43.77 $1,145 76
ROIC Compounder $6.97 $10.14 $12.90 72
Growth Earnings
Growth-Adj P/E $95.00 $135.72 $176.43 68

Widest divergence: Growth Earnings ($135.72) versus Asset-Based ($2.84). Highest evidence: Residual Income (76).

Key figures & financial health

Revenue (TTM) $700M
Revenue growth (YoY) +69.6%
Net margin 66.0%
Return on equity 113%
Free cash flow −$25.0M FY2025
P/E ratio 19.2
More key figures
Operating margin 17.0%
EPS (TTM) $2.86
EPS growth (YoY) +300%
Net debt $182M FY2025

Figures from reported company fundamentals · as of Jul 19, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 53/100

Of which business quality 52 · Market factors (momentum, volatility) 74

Profitability 85
Margins and returns on capital today
Quality Growth 72
Are margins and returns improving?
Cashflow 3
Earnings quality: real cash, not paper profit
Fin. Strength 67
Balance sheet, leverage, solvency risk
Investment 33
Disciplined investing over empire-building
Low Volatility 27
Calm price path (market factor)
Momentum 99
Price trend over the last 3–12 months (market factor)
52W Momentum 86
Distance to the 52-week high (market factor)
Net Issuance 46
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally.

Full company description

TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. The company provides BRIUMVI, an anti-CD20 monoclonal antibody for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. The company's development pipeline comprises Ublituximab IV, glycoengineered anti-CD20 mAb for the treatment of relapsing MS; TG-1701 is an orally available and covalently bound Bruton's tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening; and TG-1801, a bispecific CD47 and CD19 antibody. Its research pipeline includes various investigational medicines. The company has license agreements with LFB Biotechnologies S.A.S; GTC Biotherapeutics; LFB/GTC LLC; Ildong Pharmaceutical Co. Ltd.; and Jiangsu Hengrui Medicine Co. The company was incorporated in 1993 and is based in Morrisville, North Carolina.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

TG Therapeutics, Inc reported revenue of $616M in FY2025 versus $6.7M in FY2021, a compound +209.8%/yr. Reported net income was $447M in FY2025.

Growth Quality 59/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$616M
Latest YoY
+87.3%
Avg. growth/yr (3Y)
+504.9%
Avg. growth/yr (5Y)
+426.7%
Avg. growth/yr (29Y)
+35.1%
Revenue +209.8%/yr
FY21 $6.7M
FY22 $2.8M
FY23 $234M
FY24 $329M
FY25 $616M
Net income
FY21 −$348M
FY22 −$224M
FY23 $12.7M
FY24 $23.4M
FY25 $447M

TGTX screens 26% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "TG Therapeutics, Inc Fair Value". https://www.fairvalue-calculator.com/stock/TGTX

Recent news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 53 · Above median
Fair Value upside −26% · Above median
Return on equity (TTM) 113% · Top 25%
Return on assets 9% · Top 25%
Net margin (TTM) 66% · Top 25%
Operating margin (TTM) 17% · Top 25%
Revenue growth 70% · Top 25%
Debt / equity 0.38× · Higher than 75% of peers

Valuation Multiples vs Biotechnology median · lower = cheaper

P/E (TTM) 19.2× · Cheaper than median
P/B 12.96× · Pricier than 75% of peers
P/S (TTM) 11.99× · Pricier than 75% of peers
EV/EBITDA 57.3× · Pricier than 75% of peers
PEG 1.61× · Pricier than median

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 0 · sector 0
FUTURE 100 · sector 0
PAST 100 · sector 0
HEALTH 81 · sector 97
DIVIDEND 0 · sector 23

VALUE 0: the price sits above our fair-value range.

Insider activity: 45/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 19, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is TG Therapeutics, Inc (TGTX) overvalued or undervalued?
As of Jul 19, 2026, our model estimates a fair value of $36.86 versus a price of $49.76, about −26% (overvalued).
What is the fair value of TGTX?
Our model-based fair value for TG Therapeutics, Inc is $36.86 (as of Jul 19, 2026), built from audited fundamentals. The current price is $49.76.
What is the quality score of TGTX?
TG Therapeutics, Inc has a Quality Score of 53/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of TG Therapeutics, Inc (TGTX)?
TG Therapeutics, Inc reported trailing-twelve-month revenue of about $700M (latest available figure, as of Jul 19, 2026).
What is the net profit margin of TGTX?
The net profit margin of TG Therapeutics, Inc is about 66.0%, meaning it keeps roughly 66.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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