BioNTech SE (BNTX) fair value: what the stock is really worth
As of Nov 4, 2026: fair value (intrinsic value) of BioNTech SE stock $48.45, price $90.70, that is 46.6% below the price, quality 51 out of 100. Rating: strongly overvalued. Calculated from audited financials with 7 of our 26 valuation models and 37 quality factors, updated daily.
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BioNTech SE
BNTX · USOur calculation puts a fair price 47% below what the stock costs today.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 4, 2026.
How to read this chart
60‑month range $78.36 – $441.38 · fair‑value band $44.03 – $54.32 · the $90.70 price screens above the $48.45 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 4, 2026.
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Company profile
BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus.
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It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer.
In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma.
Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox.
The company was incorporated in 2008 and is headquartered in Mainz, Germany.
Stock analysis
BioNTech SE (BNTX) currently trades at $90.70, while our model-based Fair Value estimate is $48.45, 47% below the price, so the stock looks overvalued today.
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Valuation
Bull case: the Asset-Based group reads highest at a median of $59.90 per share, and 0 of the 7 models we run sit above the $90.70 price.
Bear case: the DCF Models group reads lowest at $48.33, and 7 of the 7 models stay below the price. Data coverage for this calculation is low.
Scenario range: $44.03 (bear) to $54.32 (bull), the price of $90.70 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 51/100 (solid quality), in the Healthcare sector.
Weak Growth: Revenue growth is inconsistent: the periods point in different directions, so there is no trend to rely on.
BioNTech SE reported revenue of €2.8B in FY2025 versus €19.0B in FY2021, a compound −38.3%/yr. Reported net income was −€1.1B in FY2025.
Key figures
Market cap $23.0B Large · P/S ratio 8.24 · EPS (TTM) $−7.77 · Net margin −63.6% · Return on equity −9.3% · Return on assets (EBIT) 29.0% · Operating margin −807% · Revenue (TTM) $2.6B.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 27 out of 100 (medium confidence).
What moves the price
The share trades about 24% below its 52-week high and 8% above its 52-week low, currently below its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at 10% fair-value upside, at −47%, BNTX screens richer than that median.
Fair Value models
All 7 models by family
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Insider trades
In the last 6 months, one officer or director sold shares worth $84.2M and none bought.
- SaleUgur SahinChief Executive Officer, 10% owner14× since Sep 3, 2026: 858,209 shares, avg. $98.15$84.2MOct 9, 202610b5-1 plan
- SaleSierk PoettingChief Operating Officer50,000 shares at $110.56$5.5MApr 22, 202610b5-1 plan
Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.
Source: SEC Form 4, as of Nov 5, 2026. All filings at the SEC ↗
Revenue & earnings trend
Growth Forecast
Recent news
- BioNTech (BNTX) Phase 3 Breast Cancer Win Comes With A Lung Safety Warning
- BioNTech and DualityBio Announce Topline Results of the DYNASTY-Breast02 Global Phase 3 Clinical Trial Evaluating Trastuzumab Pamirtecan in
- BioNTech (BNTX) Expanded Its Oncology Pipeline, Is It Still 25% Below Fair Value?
- BioNTech (BNTX) Reworks Phase 3 Breast Cancer Trial Around New Combination Approach
Compare BioNTech SE with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 559 stocks
Valuation Multiplesvs Biotechnology median · lower = cheaper
Strength profile in five axes (Snowflake)
VALUE 0: the price sits above our fair-value range.
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
- Return on equity by industry
- Quality Score by industry
- Piotroski F-Score screener with fair value
- Undervalued stocks: US Stocks
- Valuation of the USA market
Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Biotechnology stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| Incyte Corporation INCY | $122.85 | $199.23 | +62% | vs BNTX |
| Regeneron Pharmaceuticals, Inc REGN | $930.67 | $1,275 | +37% | vs BNTX |
| Genmab A/S GMAB | kr 3,635 | kr 4,068 | +12% | vs BNTX |
| Vertex Pharmaceuticals Incorporated VRTX | $549.04 | $608.47 | +11% | vs BNTX |
| WuXi Biologics (Cayman) Inc 2269 | HK$48.68 | HK$53.55 | +10% | vs BNTX |
| Samsung Biologics Co 207940 | 1,520,000 KRW | 1,644,500 KRW | +8% | vs BNTX |
| argenx SE ARGX | $931.38 | $908.40 | −2% | vs BNTX |
| BeOne Medicines AG 6160 | HK$248.60 | HK$153.56 | −38% | vs BNTX |
| Celltrion, Inc 068270 | 215,000 KRW | 74,945 KRW | −65% | vs BNTX |
| Royalty Pharma plc RPRX | $67.56 | $19.01 | −72% | vs BNTX |
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