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Crescent Biopharma, Inc (CBIO) Fair Value & Analysis

Healthcare · US · Market cap $488M

CB Crescent Biopharma, Inc logo Crescent Biopharma, Inc CBIO · US
Price$16.84
Fair Value$7.23
Upside-57.1%
Quality47/100
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Weak Growth
Thin margins · 0.0% net margin
Low debt · negative free cash flow
Trails peers (3/9)
Narrow moat 6/100
Evidence: Low Range $4.77 – $9.04 Share as image

Fair value as of: Jul 15, 2026

From 1 valuation models · updated 26 days ago

Fair value updated Jul 15, 2026, revised from $33.13 to $7.23 (−78.2%) since Jun 24, 2026. Share price +0.2% over the past month.

Below-average quality, and screening another 57% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($9.04). The favourable scenario is already priced in.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.
  • Solid but not exceptional quality (47/100) and above fair value, neither a clear bargain nor a standout compounder.
  • A fairly wide model range ($4.77 to $9.04) leaves room in how you read the outcome.
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Price vs Fair Value (5 years)

$405.00 $8.94 Fair Value $7.23 Apr 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 15, 2026.

How to read this chart

60‑month range $8.94 – $405.00 · fair‑value band $4.77 – $9.04 · the $16.84 price screens above the $7.23 fair value. Dashed = 300-day average. As of Jul 15, 2026.

Full chart & analysis →

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Analysis

Crescent Biopharma, Inc (CBIO) currently trades at $16.84, while our model-based Fair Value estimate is $7.23, implying the stock looks roughly 57.1% overvalued today. The Quality Score stands at 47/100 (below-average quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: low).

Trailing-twelve-month revenue stands at $11.9M. The balance sheet holds a net cash position of $212M. Fundamentals as of Jul 15, 2026

Our scenario range runs from $4.77 (bear case) to $9.04 (bull case); at $16.84, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 39% below its 52-week high and 93% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at -57%, CBIO screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
NCAV (Graham) $3.68 $4.93 $7.36 50
All 1 models by family
Asset-Based
NCAV (Graham) $3.68 $4.93 $7.36 50

Key figures & financial health

Revenue (TTM) $11.9M
Return on equity -161%
Free cash flow −$72.5M FY2025
Operating margin -2,380%
EPS (TTM) $-5.88
Net cash $212M FY2025

Figures from reported company fundamentals · as of Jul 15, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 47/100

Of which business quality 49 · Market factors (momentum, volatility) 43

Profitability 2
Margins and returns on capital today
Quality Growth 95
Are margins and returns improving?
Cashflow 0
Earnings quality: real cash, not paper profit
Fin. Strength 98
Balance sheet, leverage, solvency risk
Investment 21
Disciplined investing over empire-building
Low Volatility 0
Calm price path (market factor)
Momentum 64
Price trend over the last 3–12 months (market factor)
52W Momentum 57
Distance to the 52-week high (market factor)
Net Issuance 100
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003.

Full company description

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. for the development and commercialization of oncology therapeutics. The company was formerly known as GlycoMimetics, Inc. The company was founded in 2024 and is headquartered in Waltham, Massachusetts.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2020 – FY2025 · reported fiscal years

Crescent Biopharma, Inc reported revenue of $10.8M in FY2025 versus $10.2M in FY2020, a compound +1.3%/yr. Reported net income was −$154M in FY2025.

Growth Quality 6/100
Revenue growth is weak, negative or inconsistent.
Latest Revenue (FY 2025)
$10.8M
Avg. growth/yr (3Y)
+424.9%
Avg. growth/yr (5Y)
+1.3%
Avg. growth/yr (14Y)
+7.7%
Revenue +1.3%/yr
FY20 $10.2M
FY21 $1.2M
FY22 $75.0K
FY23 $10.0K
FY25 $10.8M
Net income
FY21 −$63.4M
FY22 −$46.7M
FY23 −$36.9M
FY24 −$48.5M
FY25 −$154M

CBIO screens 57% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "Crescent Biopharma, Inc Fair Value". https://www.fairvalue-calculator.com/stock/CBIO

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 49 · Above median
Fair Value upside −57% · Below median
Return on assets -69% · Bottom 25%
Net margin (TTM) 0% · Above median
Revenue growth 0% · Above median
Debt / equity 0.19× · Higher than median

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 2.40× · Pricier than median
P/S (TTM) 41.05× · Pricier than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 0 · sector 0
FUTURE 0 · sector 0
PAST 0 · sector 0
HEALTH 91 · sector 97
DIVIDEND 0 · sector 23

VALUE 0: the price sits above our fair-value range.

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 15, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is Crescent Biopharma, Inc (CBIO) overvalued or undervalued?
As of Jul 15, 2026, our model estimates a fair value of $7.23 versus a price of $16.84, about −57% (overvalued).
What is the fair value of CBIO?
Our model-based fair value for Crescent Biopharma, Inc is $7.23 (as of Jul 15, 2026), built from audited fundamentals. The current price is $16.84.
What is the quality score of CBIO?
Crescent Biopharma, Inc has a Quality Score of 47/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Crescent Biopharma, Inc (CBIO)?
Crescent Biopharma, Inc reported trailing-twelve-month revenue of about $11.9M (latest available figure, as of Jul 15, 2026).
What is the net profit margin of CBIO?
The net profit margin of Crescent Biopharma, Inc is about 0.0%, meaning it keeps roughly 0.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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