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Esperion Therapeutics, Inc (ESPR) Fair Value & Analysis

Healthcare · US · Market cap $812M

ET Esperion Therapeutics, Inc logo Esperion Therapeutics, Inc ESPR · US
Price$3.18
Fair Value$1.54
Upside-51.6%
Quality26/100
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Mixed Growth
Loss-making · -1.8% net margin
Negative equity (buybacks among others) · negative free cash flow
Trails peers (3/10)
Narrow moat 23/100
Evidence: Low Range $0.8330 – $2.24 Share as image

Fair value as of: Jul 16, 2026

From 5 valuation models · updated 25 days ago

Share price +1.0% over the past month.

Below-average quality, and screening another 52% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($2.24). The favourable scenario is already priced in.
  • Weak quality (26/100) and above fair value at the same time, the margin of safety is missing on both counts.
  • The model range is unusually wide ($0.8330 to $2.24). The outcome hinges heavily on assumptions, so read the point estimate with caution.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.
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Price vs Fair Value (5 years)

$28.69 $0.7300 Fair Value $1.54 Apr 2021 Jul 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 16, 2026.

How to read this chart

60‑month range $0.7300 – $28.69 · fair‑value band $0.8330 – $2.24 · the $3.18 price screens above the $1.54 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 16, 2026.

Full chart & analysis →

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Analysis

Esperion Therapeutics, Inc (ESPR) currently trades at $3.18, while our model-based Fair Value estimate is $1.54, implying the stock looks roughly 51.6% overvalued today. The Quality Score stands at 26/100 (below-average quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: low).

Over the trailing twelve months, Esperion Therapeutics, Inc generated revenue of $418M at a net margin of -1.8%. Revenue grew 23.2% year over year. Net debt stands at $380M. Fundamentals as of Jul 16, 2026

Our scenario range runs from $0.8330 (bear case) to $2.24 (bull case); at $3.18, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 24% below its 52-week high and 235% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -49% fair-value upside, at -52%, ESPR screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
ROIC Compounder $1.37 $1.60 $1.79 72
EPV $1.37 $1.60 $1.79 59
EV/EBITDA $2.14 $2.96 $3.78 54
All 5 models by family
Earnings-Based
EPV $1.37 $1.60 $1.79 59
Multiples
EV/EBIT $2.67 $3.66 $4.65 53
EV/EBITDA $2.14 $2.96 $3.78 54
EV/Revenue $1.81 $2.72 $3.64 43
Economic Profit
ROIC Compounder $1.37 $1.60 $1.79 72

Widest divergence: Multiples ($2.96) versus Earnings-Based ($1.60). Highest evidence: ROIC Compounder (72).

Key figures & financial health

Revenue (TTM) $418M
Revenue growth (YoY) +23.2%
Net margin -1.8%
Return on equity -261%
Free cash flow −$13.1M FY2025
Operating margin -8.2%
More key figures
Net debt $380M FY2025

Figures from reported company fundamentals · as of Jul 16, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 26/100

Of which business quality 28 · Market factors (momentum, volatility) 62

Profitability 41
Margins and returns on capital today
Quality Growth 58
Are margins and returns improving?
Cashflow 5
Earnings quality: real cash, not paper profit
Fin. Strength 27
Balance sheet, leverage, solvency risk
Investment 50
Disciplined investing over empire-building
Low Volatility 28
Calm price path (market factor)
Momentum 72
Price trend over the last 3–12 months (market factor)
52W Momentum 85
Distance to the 52-week high (market factor)
Net Issuance 0
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Esperion Therapeutics, Inc., a biopharmaceutical company, develops and commercializes medicines for the treatment of patients with elevated low density lipoprotein cholesterol (LDL-C) in the United States.

Full company description

Esperion Therapeutics, Inc., a biopharmaceutical company, develops and commercializes medicines for the treatment of patients with elevated low density lipoprotein cholesterol (LDL-C) in the United States. The company's marketed products include NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe) tablets that are oral, once-daily, non-statin medicines for the treatment of primary hyperlipidemia in adults with heterozygous familial hypercholesterolemia cardiovascular disease who require additional lowering of LDL-C. Its products also include NILEMDO, an ATP Citrate Lyase (ACL) inhibitor that lowers LDL-C and cardiovascular risk by reducing cholesterol biosynthesis and up-regulating the LDL receptors; and NUSTENDI, a bempedoic acid and ezetimibe tablet to treat elevated LDL-C. It has license and collaboration agreements with Daiichi Sankyo Co. Ltd to; Otsuka Pharmaceutical Co., Ltd; and Daiichi Sankyo Europe GmbH. Esperion Therapeutics, Inc. was formerly known as HDL Therapeutics, Inc. and changed its name to Esperion Therapeutics, Inc. in May 2008. The company was incorporated in 2008 and is headquartered in Ann Arbor, Michigan.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Esperion Therapeutics, Inc reported revenue of $403M in FY2025 versus $78.4M in FY2021, a compound +50.6%/yr. Reported net income was −$22.7M in FY2025.

Growth Quality 28/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$403M
Latest YoY
+21.3%
Avg. growth/yr (3Y)
+74.8%
Avg. growth/yr (5Y)
+12.1%
Avg. growth/yr (25Y)
+63.0%
Revenue +50.6%/yr
FY21 $78.4M
FY22 $75.5M
FY23 $116M
FY24 $332M
FY25 $403M
Net income
FY21 −$269M
FY22 −$234M
FY23 −$209M
FY24 −$51.7M
FY25 −$22.7M

ESPR screens 52% overvalued. Compare with Jiangsu Hengrui Pharmaceuticals Co →

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Cite: Fair Value Calculator (2026). "Esperion Therapeutics, Inc Fair Value". https://www.fairvalue-calculator.com/stock/ESPR

Peer Group

Drug Manufacturers - Specialty & Generic · 626 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 26 · Bottom 25%
Fair Value upside −52% · Below median
Return on assets 12% · Top 25%
Net margin (TTM) -2% · Below median
Operating margin (TTM) -8% · Bottom 25%
Revenue growth 23% · Top 25%

Valuation Multiples vs Drug Manufacturers - Specialty & Generic median · lower = cheaper

P/S (TTM) 1.94× · Pricier than median
EV/EBITDA 11.8× · Pricier than median

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 0 · sector 7
FUTURE 100 · sector 20
PAST 0 · sector 23
HEALTH 100 · sector 97
DIVIDEND 0 · sector 34

VALUE 0: the price sits above our fair-value range.

PAST 0: with negative equity (buybacks among others) return on equity is not meaningfully computable.

Insider activity: 44/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Drug Manufacturers - Specialty & Generic stocks, each showing price versus our Fair Value estimate (as of Jul 16, 2026).

Stock Price Fair Value vs Fair Value
Jiangsu Hengrui Pharmaceuticals Co 600276 ¥53.19 ¥25.94 -51%
Sun Pharmaceutical Industries Limited SUNPHARMA ₹1,933 ₹989.50 -49%
Divi's Laboratories Limited DIVISLAB ₹7,316 ₹1,943 -73%
Torrent Pharmaceuticals Limited TORNTPHARM ₹4,763 ₹1,329 -72%
PharmaEssentia Corporation 6446 1,285 TWD 221.01 TWD -83%
Cipla Limited CIPLA ₹1,439 ₹1,001 -30%
Zydus Lifesciences Limited ZYDUSLIFE ₹1,151 ₹703.32 -39%
Lupin Limited LUPIN ₹2,443 ₹2,477 +1%
Mankind Pharma Limited MANKIND ₹2,484 ₹983.11 -60%
Dr. Reddy's Laboratories Limited DRREDDY ₹1,211 ₹874.79 -28%

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Frequently asked questions

Is Esperion Therapeutics, Inc (ESPR) overvalued or undervalued?
As of Jul 16, 2026, our model estimates a fair value of $1.54 versus a price of $3.18, about −52% (overvalued).
What is the fair value of ESPR?
Our model-based fair value for Esperion Therapeutics, Inc is $1.54 (as of Jul 16, 2026), built from audited fundamentals. The current price is $3.18.
What is the quality score of ESPR?
Esperion Therapeutics, Inc has a Quality Score of 26/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Esperion Therapeutics, Inc (ESPR)?
Esperion Therapeutics, Inc reported trailing-twelve-month revenue of about $418M (latest available figure, as of Jul 16, 2026).
What is the net profit margin of ESPR?
The net profit margin of Esperion Therapeutics, Inc is about -1.8%, meaning it is currently running at a net loss. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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