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Heron Therapeutics, Inc (HRTX) Fair Value & Analysis

Healthcare · US · Market cap $79.0M

HT Heron Therapeutics, Inc logo Heron Therapeutics, Inc HRTX · US
Price$0.4908
Fair Value$0.0500
Upside-89.8%
Quality26/100
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Mixed Growth
Loss-making · -20.5% net margin
High debt · negative free cash flow
Trails peers (2/9)
Narrow moat 12/100
Evidence: Low Range $0.0400 – $0.0800 Share as image

Fair value as of: Jul 17, 2026

From 1 valuation models · updated 25 days ago

Fair value updated Jul 17, 2026, revised from $0.3400 to $0.0500 (−85.3%) since Jun 24, 2026. Share price +10.2% over the past month.

Below-average quality, and screening another 90% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($0.0800). The favourable scenario is already priced in.
  • Weak quality (26/100) and above fair value at the same time, the margin of safety is missing on both counts.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.
  • A fairly wide model range ($0.0400 to $0.0800) leaves room in how you read the outcome.
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Price vs Fair Value (5 years)

$18.48 $0.3820 Fair Value $0.0500 Apr 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 17, 2026.

How to read this chart

60‑month range $0.3820 – $18.48 · fair‑value band $0.0400 – $0.0800 · the $0.4908 price screens above the $0.0500 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 17, 2026.

Full chart & analysis →

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Analysis

Heron Therapeutics, Inc (HRTX) currently trades at $0.4908, while our model-based Fair Value estimate is $0.0500, implying the stock looks roughly 89.8% overvalued today. The Quality Score stands at 26/100 (below-average quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: low).

Over the trailing twelve months, Heron Therapeutics, Inc generated revenue of $151M at a net margin of -20.5%. Revenue declined 10.8% year over year. Net debt stands at $112M. Fundamentals as of Jul 17, 2026

Our scenario range runs from $0.0400 (bear case) to $0.0800 (bull case); at $0.4908, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 79% below its 52-week high and 28% above its 52-week low, currently below its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at -90%, HRTX screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
NCAV (Graham) $0.0400 $0.0500 $0.0800 50
All 1 models by family
Asset-Based
NCAV (Graham) $0.0400 $0.0500 $0.0800 50

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Key figures & financial health

Revenue (TTM) $151M
Revenue growth (YoY) -10.8%
Net margin -20.5%
Return on equity -2,409%
Free cash flow −$27.9M FY2025
Operating margin -13.7%
More key figures
EPS (TTM) $-0.1800
Net debt $112M FY2025

Figures from reported company fundamentals · as of Jul 17, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 26/100

Of which business quality 26 · Market factors (momentum, volatility) 3

Profitability 24
Margins and returns on capital today
Quality Growth 33
Are margins and returns improving?
Cashflow 19
Earnings quality: real cash, not paper profit
Fin. Strength 9
Balance sheet, leverage, solvency risk
Investment 96
Disciplined investing over empire-building
Low Volatility 9
Calm price path (market factor)
Momentum 0
Price trend over the last 3–12 months (market factor)
52W Momentum 3
Distance to the 52-week high (market factor)
Net Issuance 0
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Heron Therapeutics, Inc., a commercial-stage biotechnology company, engages in developing and commercializing therapeutic that enhances medical care.

Full company description

Heron Therapeutics, Inc., a commercial-stage biotechnology company, engages in developing and commercializing therapeutic that enhances medical care. The company's product candidates utilize its proprietary Biochronomer, a drug delivery technology, which delivers therapeutic levels of a range of short-acting pharmacological agents over a period from days to weeks with a single administration. It offers SUSTOL (granisetron), an extended-release injection for the prevention of acute and delayed nausea and vomiting associated with moderately emetogenic chemotherapy, or anthracycline and cyclophosphamide combination chemotherapy regimens; and CINVANTI, an intravenous formulation of aprepitant, a substance P/neurokinin-1 receptor antagonist for the prevention of acute and delayed nausea and vomiting associated with highly emetogenic cancer chemotherapy, as well as nausea and vomiting associated with moderately emetogenic cancer chemotherapy. The company is also developing ZYNRELEF, a dual-acting local anesthetic that delivers a fixed-dose combination of the local anesthetic bupivacaine and a low dose of the nonsteroidal anti-inflammatory drug meloxicam; and APONVIE, an intravenous formulation of a substance P/neurokinin-1 receptor antagonist indicated for the prevention of postoperative nausea and vomiting in adults. Heron Therapeutics, Inc. was formerly known as A.P. Pharma, Inc. and changed its name to Heron Therapeutics, Inc. in January 2014. The company was founded in 1983 and is headquartered in Cary, North Carolina.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Heron Therapeutics, Inc reported revenue of $155M in FY2025 versus $86.3M in FY2021, a compound +15.7%/yr. Reported net income was −$20.2M in FY2025.

Growth Quality 30/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$155M
Latest YoY
+7.4%
Avg. growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+12.9%
Avg. growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+11.8%
Avg. growth/yr (38Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+12.6%
Revenue +15.7%/yr
FY21 $86.3M
FY22 $108M
FY23 $127M
FY24 $144M
FY25 $155M
Net income
FY21 −$218M
FY22 −$135M
FY23 −$111M
FY24 −$13.6M
FY25 −$20.2M

HRTX screens 90% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "Heron Therapeutics, Inc Fair Value". https://www.fairvalue-calculator.com/stock/HRTX

Earlier news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Biotechnology · 605 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 26 · Bottom 25%
Fair Value upside −90% · Bottom 25%
Return on assets -3% · Above median
Net margin (TTM) -21% · Bottom 25%
Operating margin (TTM) -14% · Below median
Revenue growth -11% · Below median
Debt / equity 9.81× · Higher than 75% of peers

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 5.51× · Pricier than 75% of peers
P/S (TTM) 0.52× · Cheaper than 75% of peers

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 17, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
RemeGen Co 688331 ¥134.45 ¥23.19 -83%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is Heron Therapeutics, Inc (HRTX) overvalued or undervalued?
As of Jul 17, 2026, our model estimates a fair value of $0.0500 versus a price of $0.4908, about −90% (overvalued).
What is the fair value of HRTX?
Our model-based fair value for Heron Therapeutics, Inc is $0.0500 (as of Jul 17, 2026), built from audited fundamentals. The current price is $0.4908.
What is the quality score of HRTX?
Heron Therapeutics, Inc has a Quality Score of 26/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Heron Therapeutics, Inc (HRTX)?
Heron Therapeutics, Inc reported trailing-twelve-month revenue of about $151M (latest available figure, as of Jul 17, 2026).
What is the net profit margin of HRTX?
The net profit margin of Heron Therapeutics, Inc is about -20.5%, meaning it is currently running at a net loss. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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