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SeaStar Medical Holding Corporation (ICU) Fair Value & Analysis

Healthcare · US · Market cap $12.7M · ISIN US81256L3024

What is SeaStar Medical Holding Corporation really worth?

SM SeaStar Medical Holding Corporation logo SeaStar Medical Holding Corporation ICU · US
Price$3.13
Fair Value$2.09
Upside−33.2%
Quality34/100

Below-average quality, and trading another 50% above our fair value of $2.09.

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Risks

!Mixed Growth (revenue YoY +814.1 %/yr)
!Thin margins · 0.0% net margin
!Low debt · negative free cash flow
!Mixed vs. peers (4/9)
!Narrow moat 8/100
!Evidence only low, so the estimate is less certain
Evidence: Low Range $1.38 – $2.62

Fair value as of: Aug 18, 2026

From 1 valuation models · updated 14 days ago

What runs behind every stock

69 individual criteria per stock, every one traceable See the method →

What matters now

  • The price sits above even our optimistic bull case ($2.62). The favourable scenario is already priced in.
  • Weak quality (34/100) and above fair value at the same time, the margin of safety is missing on both counts.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.
  • A fairly wide model range ($1.38 to $2.62) leaves room in how you read the outcome.

Price vs Fair Value (5 years)

$3,088 $2.21 Fair Value $2.09 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Aug 18, 2026.

How to read this chart

60‑month range $2.21 – $3,088 · fair‑value band $1.38 – $2.62 · the $3.13 price screens above the $2.09 fair value. Dashed = 300-day average. As of Aug 18, 2026.

Full chart & analysis →

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Analysis

SeaStar Medical Holding Corporation (ICU) currently trades at $3.13, while our model-based Fair Value estimate is $2.09, implying the stock looks roughly 49.7% overvalued today. The Quality Score stands at 34/100 (below-average quality), in the Healthcare sector. How firm this estimate is: it rests on 1 models at a data quality of 95/100, which puts the evidence level at low.

Trailing-twelve-month revenue stands at $1.4M. Revenue grew 68.9% year over year. The balance sheet holds a net cash position of $11.5M. Fundamentals as of Aug 18, 2026

Our scenario range runs from $1.38 (bear case) to $2.62 (bull case); at $3.13, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 75% below its 52-week high and 51% above its 52-week low, currently below its 200-day average. For context, the median of 10 Healthcare peers we cover trades at −59% fair-value upside, at −33%, ICU screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted, family-balanced blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small. Every input is real reported data, nothing guessed.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
NCAV (Graham) best evidence $1.30 $1.75 $2.61 54
All 1 models by family
Asset-Based
NCAV (Graham) best evidence $1.30 $1.75 $2.61 54

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Key figures & financial health

P/S ratio 8.68 TTM
EPS (TTM) $−2.37
Return on equity −302% TTM
Return on assets (EBIT) −399% avg 5y
Operating margin −728% TTM
Revenue (TTM) $1.4M TTM
More key figures
Growth
Revenue growth (YoY) +68.9%
Balance sheet & cash flow
Free cash flow −$13.6M FY2025
Net cash $11.5M FY2025

Figures from reported company fundamentals · as of Aug 18, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 34/100

Of which business quality 38 · Market factors (momentum, volatility) 29

Profitability 3
Margins and returns on capital today
Quality Growth 77
Are margins and returns improving?
Cashflow 35
Earnings quality: real cash, not paper profit
Fin. Strength 69
Balance sheet, leverage, solvency risk
Investment 50
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 30
Price trend over the last 3–12 months (market factor)
52W Momentum 5
Distance to the 52-week high (market factor)
Net Issuance 0
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

All values are scores from 0 to 100 (100 = best against fixed, research-based bands), not percentages. The three market factors (momentum, 52-week proximity, low volatility) are displayed but carry zero weight in the headline number: market sentiment is not a business property.

About the company

SeaStar Medical Holding Corporation, a commercial-stage healthcare company, develops a proprietary platform therapy to reduce the consequences of hyperinflammation on vital organs in the United States.

Full company description

SeaStar Medical Holding Corporation, a commercial-stage healthcare company, develops a proprietary platform therapy to reduce the consequences of hyperinflammation on vital organs in the United States. The company offers the selective cytopheretic device (SCD), which is a disease-modifying device that neutralizes over-active immune cells and stops the cytokine storm that yields destructive hyperinflammation; and QUELIMMUNE, an SCD therapy for pediatric patients with acute kidney injury (AKI) due to sepsis. It also develops NEUTRALIZE-AKI, an SCD therapy that is in clinical trials for adult patients with AKI; and other products in various therapeutic areas, including cardiorenal syndrome, hepatorenal syndrome, and myocardial stunning in end-stage renal disease. SeaStar Medical Holding Corporation was founded in 2007 and is headquartered in Denver, Colorado.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

SeaStar Medical Holding Corporation reported revenue of $1.2M in FY2025 versus $0 in FY2021. Reported net income was −$12.2M in FY2025.

Growth Quality 28/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$1.2M
Latest YoY
+814.1%
Value creation/yr We only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed
Revenue
FY21 $0
FY22 $0
FY23 $0
FY24 $135K
FY25 $1.2M
Net income
FY21 −$4.6M
FY22 −$23.0M
FY23 −$26.2M
FY24 −$24.8M
FY25 −$12.2M

ICU screens 50% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "SeaStar Medical Holding Corporation Fair Value". https://www.fairvalue-calculator.com/stock/ICU

Peer Group

Biotechnology · 641 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 38 · Below median
Fair Value upside −33% · Above median
Return on assets −79% · Bottom 25%
Net margin (TTM) 0% · Above median
Revenue growth 69% · Top 25%
Debt / equity 0.42× · Higher than 75% of peers

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 1.22× · Cheaper than median
P/S (TTM) 8.85× · Pricier than median

Strength profile in five axes (Snowflake)

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE0 · sector 0
FUTURE100 · sector 0
PAST0 · sector 0
HEALTH79 · sector 98
DIVIDEND0 · sector 26

VALUE 0: the price sits above our fair-value range.

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Aug 18, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $547.55 $278.78 −49%
Regeneron Pharmaceuticals, Inc REGN $807.71 $594.40 −26%
argenx SE ARGX €877.60 €292.84 −67%
Samsung Biologics Co 207940 1,518,000 KRW 1,055,793 KRW −30%
CSL Limited CSL A$173.88 A$142.22 −18%
Alnylam Pharmaceuticals, Inc ALNY $228.61 $51.70 −77%
Royalty Pharma plc RPRX $60.58 $24.22 −60%
Celltrion, Inc 068270 190,700 KRW 74,519 KRW −61%
BeOne Medicines AG ONC $362.51 $111.35 −69%
BioNTech SE BNTX $111.40 $45.66 −59%

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Frequently asked questions

Is SeaStar Medical Holding Corporation (ICU) overvalued or undervalued?
As of Aug 18, 2026, our model estimates a fair value of $2.09 versus a price of $3.13, about −33% upside (overvalued).
What is the fair value of ICU?
Our model-based fair value for SeaStar Medical Holding Corporation is $2.09 (as of Aug 18, 2026), built from audited fundamentals. The current price: $3.13.
What is the quality score of ICU?
SeaStar Medical Holding Corporation has a Quality Score of 34/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of SeaStar Medical Holding Corporation (ICU)?
SeaStar Medical Holding Corporation reported trailing-twelve-month revenue of about $1.4M (latest available figure, as of Aug 18, 2026).
What is the net profit margin of ICU?
The net profit margin of SeaStar Medical Holding Corporation is about 0.0%, meaning it keeps roughly 0.0% of revenue as net income. Based on the latest reported figures.
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