Illumina Inc (ILMN) fair value: what the stock is really worth
As of Nov 4, 2026: fair value (intrinsic value) of Illumina Inc stock $262, price $227, upside +15.7%, quality 83 out of 100. Rating: undervalued. Calculated from audited financials with 24 of our 26 valuation models and 37 quality factors, updated daily.
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Illumina Inc
ILMN · USThe stock costs 14% less than our calculation considers fair.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 4, 2026.
How to read this chart
60‑month range $70.30 – $510.54 · fair‑value band $145.54 – $355.23 · the $226.54 price screens below the $262.03 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 4, 2026.
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Company profile
Illumina, Inc. provides sequencing- and array-based solutions for genetic and genomic analysis in the Americas, Europe, Greater China, the Asia Pacific, the Middle East, and Africa.
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The company offers sequencing- and array-based instruments and consumables, which include reagents, flow cells, and library preparation; whole-genome sequencing kits, which sequence entire genomes of various size and complexity; and targeted resequencing kits, which sequence exomes, specific genes, and RNA or other genomic regions of interest.
It also provides whole-genome sequencing, genotyping, noninvasive prenatal testing, and product support services.
The company serves genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, commercial molecular diagnostic laboratories, and consumer genomics companies.
The company markets and distributes its products directly to customers, as well as through life-science distributors.
The company has a collaboration with Labcorp Holdings Inc. for the development of oncology treatments through applications of sequencing solutions across the healthcare ecosystem; and strategic collaboration with Integrated DNA Technologies to enable a DRAGEN, secondary analysis pipeline for IDT xGena, FFPE and cfDNA next generation sequencing (NGS) library preparation with custom panels, delivering an integrated, end-to-end solution for somatic oncology research.
It also has a data partnership with Center for Data-Driven Discovery in Biomedicine to advance research in pediatric cancer and rare disease. Illumina, Inc. was incorporated in 1998 and is headquartered in San Diego, California.
Stock analysis
Illumina Inc (ILMN) currently trades at $226.54, while our model-based Fair Value estimate is $262.03, implying the stock looks roughly 14% undervalued today.
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Valuation
Bull case: the Growth Earnings group reads highest at a median of $154.16 per share, and 1 of the 24 models we run sit above the $226.54 price.
Bear case: the Economic Profit group reads lowest at $49.13, and 23 of the 24 models stay below the price. Data coverage for this calculation is medium.
Scenario range: $145.54 (bear) to $355.23 (bull), the price of $226.54 sits inside it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 83/100 (high quality), in the Healthcare sector.
Mixed Growth: Spin-off in 2024: revenue and profit before it include the divested business. Growth is measured afresh from 2024.
Illumina Inc reported revenue of $4.3B in FY2025 versus $4.5B in FY2021, a compound −1.1%/yr. Reported net income was $850M in FY2025, compounding +2.8%/yr from FY2021.
Key figures
Market cap $34.7B Large · P/E ratio 39.0 · P/S ratio 7.64 · EPS (TTM) $5.81 · Net margin 19.7% · Return on equity 32.4% · Return on assets (EBIT) −9.1% · Operating margin 20.0%.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 77 out of 100 (low confidence).
What moves the price
The share trades about 23% below its 52-week high and 98% above its 52-week low, currently above its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at −29% fair-value upside, at 16%, ILMN screens cheaper than that median.
Fair Value models
All 24 models by family
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Insider trades
In the last 6 months, 5 officers or directors sold shares worth $592.2M and none bought.
- SaleKeith A. MeisterDirector6× since May 13, 2026: 3,059,258 shares, avg. $193.23$591.1MSep 4, 2026
- SaleChristensen Jakob WedelSVP, Strategy/Corp Development3× since Dec 8, 2025: 2,282 shares, avg. $160.45$366,137Aug 18, 202610b5-1 plan
- SaleScott M DaviesChief Legal Officer5× since Dec 12, 2025: 3,504 shares, avg. $151.62$531,274Jul 30, 202610b5-1 plan
- SalePatricia LeckmanSVP, Chief People Officer3× since Feb 18, 2026: 3,937 shares, avg. $134.55$529,719Jun 5, 202610b5-1 plan
- SaleScott D EricksenVP, Chief Accounting Officer2,000 shares at $152.58$305,150May 29, 202610b5-1 plan
- BuyScott GottliebDirector200 shares at $117.81$23,562Feb 9, 2026
Plus 20 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.
Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.
Source: SEC Form 4, as of Nov 4, 2026. All filings at the SEC ↗
Revenue & earnings trend
Growth Forecast
Watch ILMN, get fair value alerts →
Recent news
- Illumina (ILMN) Selected For Singapore Genome Sequencing Program Covering 450,000 People
- Illumina, Inc. (ILMN) Rallied, but Mott Capital Decided to Take Some Profits: Here’s Why
Compare Illumina Inc with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Diagnostics & Research · 126 stocks
Valuation Multiplesvs Diagnostics & Research median · lower = cheaper
Strength profile in five axes (Snowflake)
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
- Quality Score by industry
- Return on equity by industry
- Stock screener with 62 metrics
- Undervalued stocks: US Stocks
- Valuation of the USA market
Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Diagnostics & Research stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| IQVIA Holdings IQV | $263.79 | $288.85 | +10% | vs ILMN |
| WuXi AppTec Co 603259 | ¥154.46 | ¥164.66 | +7% | vs ILMN |
| Thermo Fisher Scientific Inc TMO | $706.16 | $686.04 | −3% | vs ILMN |
| Danaher Corporation DHR | $234.93 | $209.18 | −11% | vs ILMN |
| IDEXX Laboratories, Inc IDXX | $698.55 | $496.48 | −29% | vs ILMN |
| Labcorp Holdings LH | $367.79 | $230.82 | −37% | vs ILMN |
| Mettler-Toledo International Inc MTD | $1,723 | $648.30 | −62% | vs ILMN |
| Agilent Technologies, Inc A | $177.17 | $64.53 | −64% | vs ILMN |
| Lonza Group LONN | CHF 672.40 | CHF 153.50 | −77% | vs ILMN |
| Waters Corporation WAT | $467.60 | $91.26 | −80% | vs ILMN |
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