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Kaleido Biosciences, Inc (KLDO) Fair Value & Analysis

Healthcare · US · Market cap $4.3K

KB Kaleido Biosciences, Inc logo Kaleido Biosciences, Inc KLDO · US
Price$0.0001
Fair Value$0.0001
Upside+0.0%
Quality38/100
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Mixed Growth
Thin margins · 0.0% net margin
Moderate debt · negative free cash flow
Mixed vs. peers (3/6)
Narrow moat 6/100
Evidence: Low Range $0.0001 – $0.0001 Share as image

Fair value as of: Aug 18, 2026

From 1 valuation models · updated today

Below-average quality, currently priced close to our fair value.

What matters now

  • The price sits close to our fair value, market and models broadly agree here, little valuation tension.
  • Evidence is limited here (fewer models, shorter history), so the fair value is a rougher estimate than usual.
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Price vs Fair Value (5 years)

$7.99 $0.0001 Fair Value $0.0001 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Aug 18, 2026.

How to read this chart

60‑month range $0.0001 – $7.99 · the $0.0001 price screens below the $0.0001 fair value. Dashed = 300-day average. As of Aug 18, 2026.

Full chart & analysis →

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Analysis

Kaleido Biosciences, Inc (KLDO) currently trades at $0.0001, while our model-based Fair Value estimate is $0.0001, implying the stock looks roughly 0.0% fairly valued today. The Quality Score stands at 38/100 (below-average quality), in the Healthcare sector. Bull case: trading below our estimate, it may offer upside if the fundamentals hold. Bear case: a low price can be a value trap when quality is weak or the data is thin (evidence: low), always confirm before acting.

Trailing-twelve-month revenue stands at $1.1M. Revenue grew 102.5% year over year. The balance sheet holds a net cash position of $16.8M. Fundamentals as of Aug 18, 2026

For context, the median of 10 Healthcare peers we cover trades at -47% fair-value upside, at 0%, KLDO screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
NCAV (Graham) $0.0001 $0.0001 $0.0001 50
All 1 models by family
Asset-Based
NCAV (Graham) $0.0001 $0.0001 $0.0001 50

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Key figures & financial health

Revenue (TTM) $1.1M
Revenue growth (YoY) +103%
Return on equity -581%
Free cash flow −$78.2M FY2021
Operating margin -3,974%
EPS (TTM) $-2.16
More key figures
Net cash $16.8M FY2021

Figures from reported company fundamentals · as of Aug 18, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 38/100

Of which business quality 39 · Market factors (momentum, volatility) 41

Profitability 0
Margins and returns on capital today
Quality Growth 43
Are margins and returns improving?
Cashflow 31
Earnings quality: real cash, not paper profit
Fin. Strength 49
Balance sheet, leverage, solvency risk
Investment 100
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 40
Price trend over the last 3–12 months (market factor)
52W Momentum 33
Distance to the 52-week high (market factor)
Net Issuance 40
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Kaleido Biosciences, Inc., a clinical-stage healthcare company, develops microbiome metabolic therapies. The company develops KB195 for the treatment of patients with urea cycle disorder; KB295 to treat ulcerative colitis; KB174 for the treatment of hepatic encephalopathy; and KB109 to treat COVID-19 disease.

Full company description

Kaleido Biosciences, Inc., a clinical-stage healthcare company, develops microbiome metabolic therapies. The company develops KB195 for the treatment of patients with urea cycle disorder; KB295 to treat ulcerative colitis; KB174 for the treatment of hepatic encephalopathy; and KB109 to treat COVID-19 disease. It also develops programs for the treatment of ulcerative colitis, psoriasis, atopic immune disease, chronic obstructive pulmonary disease pathogens, and immuno-oncology. The company has collaboration agreements with Institute Gustave Roussy, Washington University, and Janssen. Kaleido Biosciences, Inc. was incorporated in 2015 and is headquartered in Lexington, Massachusetts.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2017 – FY2021 · reported fiscal years

Kaleido Biosciences, Inc reported revenue of $1.1M in FY2021 versus $0 in FY2017. Reported net income was −$90.3M in FY2021.

Growth Quality 26/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2021)
$1.1M
Latest YoY
+13.2%
Revenue
FY17 $0
FY18 $0
FY19 $0
FY20 $975K
FY21 $1.1M
Net income
FY17 −$27.6M
FY18 −$61.7M
FY19 −$85.0M
FY20 −$79.8M
FY21 −$90.3M

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Cite: Fair Value Calculator (2026). "Kaleido Biosciences, Inc Fair Value". https://www.fairvalue-calculator.com/stock/KLDO

Peer Group

Biotechnology · 599 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 39 · Below median
Fair Value upside +0% · Top 25%
Return on assets -100% · Bottom 25%
Net margin (TTM) 0% · Above median
Revenue growth 103% · Top 25%
Debt / equity 0.52× · Higher than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 33 · sector 0
FUTURE 100 · sector 0
PAST 0 · sector 0
HEALTH 74 · sector 97
DIVIDEND 0 · sector 29

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Aug 18, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $525.73 $278.78 -47%
Regeneron Pharmaceuticals, Inc REGN $797.99 $594.40 -26%
Samsung Biologics Co 207940 1,549,000 KRW 1,055,793 KRW -32%
Celltrion, Inc 068270 202,000 KRW 74,519 KRW -63%
WuXi Biologics (Cayman) Inc 2269 HK$45.70 HK$30.58 -33%
Innovent Biologics, Inc 1801 HK$95.55 HK$19.68 -79%
Genmab A/S GMAB kr 2,037 kr 250.07 -88%
Sino Biopharmaceutical Limited 1177 HK$4.87 HK$3.37 -31%
RemeGen Co 688331 ¥131.87 ¥23.19 -82%
ALTEOGEN Inc 196170 314,000 KRW 39,476 KRW -87%

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Frequently asked questions

Is Kaleido Biosciences, Inc (KLDO) overvalued or undervalued?
As of Aug 18, 2026, our model estimates a fair value of $0.0001 versus a price of $0.0001, about +0% (fairly valued).
What is the fair value of KLDO?
Our model-based fair value for Kaleido Biosciences, Inc is $0.0001 (as of Aug 18, 2026), built from audited fundamentals. The current price is $0.0001.
What is the quality score of KLDO?
Kaleido Biosciences, Inc has a Quality Score of 38/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Kaleido Biosciences, Inc (KLDO)?
Kaleido Biosciences, Inc reported trailing-twelve-month revenue of about $1.1M (latest available figure, as of Aug 18, 2026).
What is the net profit margin of KLDO?
The net profit margin of Kaleido Biosciences, Inc is about 0.0%, meaning it keeps roughly 0.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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