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Kiniksa Pharmaceuticals International, plc (KNSA) Fair Value & Analysis

Healthcare · US · Market cap $4.9B

KP Kiniksa Pharmaceuticals International, plc logo Kiniksa Pharmaceuticals International, plc KNSA · US
Price$76.06
Fair Value$13.57
Upside-82.2%
Quality56/100
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Mixed Growth
Thin margins · 9.7% net margin
generates free cash flow
Mixed vs. peers (6/12)
Moderate moat 54/100
Evidence: High Range $9.38 – $16.54 Share as image

Fair value as of: Jul 20, 2026

From 24 valuation models · updated 20 days ago

Share price +17.4% over the past month.

A solid business, but screening 82% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($16.54). The favourable scenario is already priced in.
  • Solid but not exceptional quality (56/100) and above fair value, neither a clear bargain nor a standout compounder.
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Price vs Fair Value (5 years)

$80.92 $7.60 Fair Value $13.57 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 20, 2026.

How to read this chart

60‑month range $7.60 – $80.92 · fair‑value band $9.38 – $16.54 · the $76.06 price screens above the $13.57 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 20, 2026.

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Analysis

Kiniksa Pharmaceuticals International, plc (KNSA) currently trades at $76.06, while our model-based Fair Value estimate is $13.57, implying the stock looks roughly 82.2% overvalued today. The Quality Score stands at 56/100 (solid quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: high).

Over the trailing twelve months, Kiniksa Pharmaceuticals International, plc generated revenue of $754M at a net margin of 9.7%. Revenue grew 55.5% year over year. It earns a return on equity of 13.7%. The balance sheet holds a net cash position of $156M. Fundamentals as of Jul 20, 2026

Our scenario range runs from $9.38 (bear case) to $16.54 (bull case); at $76.06, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades near its 52-week high and 190% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -49% fair-value upside, at -82%, KNSA screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Growth DCF $11.77 $19.18 $31.11 72
Growth-Adj P/E $41.44 $59.20 $76.97 68
Rev-Margin DCF $19.72 $34.66 $65.76 67
All 24 models by family
DCF Models
FCF DCF $12.31 $17.02 $31.70 38
Owner Earnings $22.95 $46.52 $94.17 31
5Y Revenue Exit $18.08 $30.79 $57.56 39
5Y EBITDA Exit $19.29 $33.23 $60.63 41
5Y P/E Exit $21.60 $46.87 $81.83 38
10Y Revenue Exit $15.90 $35.34 $49.19 36
10Y EBITDA Exit $17.42 $37.88 $74.68 37
10Y P/E Exit $19.06 $42.75 $82.83 35
Earnings-Based
Graham-Dodd $8.67 $60.43 $84.81 54
Lynch FV $31.22 $44.60 $57.98 50
PEG = 1.0 $31.22 $44.60 $57.98 46
EPV $12.87 $14.34 $15.61 59
Multiples
P/E Multiple $21.03 $28.03 $35.04 63
P/S Multiple $16.25 $21.66 $27.08 58
P/B Multiple $16.25 $21.66 $27.08 55
EV/EBIT $24.84 $31.93 $39.02 53
EV/EBITDA $21.47 $27.44 $33.40 54
EV/Revenue $18.75 $25.26 $31.76 43
Asset-Based
NCAV (Graham) $6.13 $8.21 $12.26 50
Growth DCF
Growth DCF $11.77 $19.18 $31.11 72
Rev-Margin DCF $19.72 $34.66 $65.76 67
Economic Profit
Residual Income $10.72 $11.94 $19.38 61
ROIC Compounder $13.70 $17.58 $21.31 67
Growth Earnings
Growth-Adj P/E $41.44 $59.20 $76.97 68

Widest divergence: Growth Earnings ($59.20) versus Asset-Based ($8.21). Highest evidence: Growth DCF (72).

Key figures & financial health

Revenue (TTM) $754M
Revenue growth (YoY) +55.5%
Net margin 9.7%
Return on equity 13.7%
Free cash flow $25.4M FY2025
P/E ratio 70.3
More key figures
Operating margin 13.7%
EPS (TTM) $0.9100
EPS growth (YoY) +146%
Net cash $156M FY2025

Figures from reported company fundamentals · as of Jul 20, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 56/100

Of which business quality 59 · Market factors (momentum, volatility) 88

Profitability 59
Margins and returns on capital today
Quality Growth 80
Are margins and returns improving?
Cashflow 39
Earnings quality: real cash, not paper profit
Fin. Strength 95
Balance sheet, leverage, solvency risk
Investment 48
Disciplined investing over empire-building
Low Volatility 64
Calm price path (market factor)
Momentum 98
Price trend over the last 3–12 months (market factor)
52W Momentum 100
Distance to the 52-week high (market factor)
Net Issuance 21
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Kiniksa Pharmaceuticals International, plc, a biopharmaceutical company, develops and commercializes medical therapies in the United States, the United Kingdom, and internationally.

Full company description

Kiniksa Pharmaceuticals International, plc, a biopharmaceutical company, develops and commercializes medical therapies in the United States, the United Kingdom, and internationally. The company offers ARCALYST, an interleukin-1alpha and 1beta cytokine trap for the treatment of recurrent pericarditis, a chronic autoinflammatory cardiovascular disease and cardiac sarcoidosis. It also develops KPL-387, an investigational and fully human immunoglobulin G2 monoclonal antibody, which is Phase 2/3 clinical trial for the treatment of recurrent pericarditis; and KPL-116, a Fc-modified immunoglobulin G2 monoclonal antibody, which is in pre-clinical stage. The company was formerly known as Kiniksa Pharmaceuticals, Ltd. and changed its name to Kiniksa Pharmaceuticals International, plc in June 2024. Kiniksa Pharmaceuticals International, plc was incorporated in 2015 and is based in London, the United Kingdom.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Kiniksa Pharmaceuticals International, plc reported revenue of $678M in FY2025 versus $38.5M in FY2021, a compound +104.8%/yr. Reported net income was $59.0M in FY2025.

Growth Quality 68/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$678M
Latest YoY
+60.1%
Avg. growth/yr (3Y)
+45.5%
Avg. growth/yr (5Y)
+144.8%
Revenue +104.8%/yr
FY21 $38.5M
FY22 $220M
FY23 $270M
FY24 $423M
FY25 $678M
Net income
FY21 −$158M
FY22 $183M
FY23 $14.1M
FY24 −$43.2M
FY25 $59.0M

KNSA screens 82% overvalued. Compare with Jiangsu Hengrui Pharmaceuticals Co →

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Cite: Fair Value Calculator (2026). "Kiniksa Pharmaceuticals International, plc Fair Value". https://www.fairvalue-calculator.com/stock/KNSA

Recent news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Drug Manufacturers - Specialty & Generic · 626 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 56 · Above median
Fair Value upside −82% · Bottom 25%
Return on equity (TTM) 14% · Top 25%
Return on assets 8% · Top 25%
Net margin (TTM) 10% · Above median
Operating margin (TTM) 14% · Above median
Revenue growth 56% · Top 25%

Valuation Multiples vs Drug Manufacturers - Specialty & Generic median · lower = cheaper

P/E (TTM) 70.3× · Pricier than 75% of peers
P/B 8.67× · Pricier than 75% of peers
P/S (TTM) 6.53× · Pricier than 75% of peers
P/FCF 193.6× · Pricier than 75% of peers
EV/EBITDA 50.1× · Pricier than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 0 · sector 7
FUTURE 100 · sector 20
PAST 55 · sector 23
HEALTH 0 · sector 97
DIVIDEND 0 · sector 34

VALUE 0: the price sits above our fair-value range.

Insider activity: 40/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Drug Manufacturers - Specialty & Generic stocks, each showing price versus our Fair Value estimate (as of Jul 20, 2026).

Stock Price Fair Value vs Fair Value
Jiangsu Hengrui Pharmaceuticals Co 600276 ¥53.19 ¥25.94 -51%
Sun Pharmaceutical Industries Limited SUNPHARMA ₹1,933 ₹989.50 -49%
Divi's Laboratories Limited DIVISLAB ₹7,316 ₹1,943 -73%
Torrent Pharmaceuticals Limited TORNTPHARM ₹4,763 ₹1,329 -72%
PharmaEssentia Corporation 6446 1,285 TWD 221.01 TWD -83%
Cipla Limited CIPLA ₹1,439 ₹1,001 -30%
Zydus Lifesciences Limited ZYDUSLIFE ₹1,151 ₹703.32 -39%
Lupin Limited LUPIN ₹2,443 ₹2,477 +1%
Mankind Pharma Limited MANKIND ₹2,484 ₹983.11 -60%
Dr. Reddy's Laboratories Limited DRREDDY ₹1,211 ₹874.79 -28%

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Frequently asked questions

Is Kiniksa Pharmaceuticals International, plc (KNSA) overvalued or undervalued?
As of Jul 20, 2026, our model estimates a fair value of $13.57 versus a price of $76.06, about −82% (overvalued).
What is the fair value of KNSA?
Our model-based fair value for Kiniksa Pharmaceuticals International, plc is $13.57 (as of Jul 20, 2026), built from audited fundamentals. The current price is $76.06.
What is the quality score of KNSA?
Kiniksa Pharmaceuticals International, plc has a Quality Score of 56/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Kiniksa Pharmaceuticals International, plc (KNSA)?
Kiniksa Pharmaceuticals International, plc reported trailing-twelve-month revenue of about $754M (latest available figure, as of Jul 20, 2026).
What is the net profit margin of KNSA?
The net profit margin of Kiniksa Pharmaceuticals International, plc is about 9.7%, meaning it keeps roughly 9.7% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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