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Lakefront Biotherapeutics NV (LKFT) Fair Value & Analysis

Healthcare · US · Market cap $1.9B

LB Lakefront Biotherapeutics NV logo Lakefront Biotherapeutics NV LKFT · US
Price$27.00
Fair Value$81.00
Upside+200.0%
Quality70/100
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Expensive Growth
Highly profitable · 46.8% net margin
negative free cash flow
Ranks above peers (9/10)
Wide moat 72/100
Evidence: High Range $60.75 – $111.29 Share as image

Fair value as of: Jul 24, 2026

From 15 valuation models · updated 17 days ago

Fair value updated Jul 24, 2026, revised from $110.85 to $81.00 (−26.9%) since Jun 25, 2026. Share price −12.4% over the past month.

A solid business, screening 200% undervalued on our models.

What matters now

  • The rarer combination: high quality (70/100) AND below fair value. That earns a closer look rather than a quick verdict.
  • The price is below even our cautious bear case ($60.75). The market is more pessimistic than our downside scenario.
  • A fairly wide model range ($60.75 to $111.29) leaves room in how you read the outcome.
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Price vs Fair Value (5 years)

$80.67 $22.69 Fair Value $81.00 Apr 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 24, 2026.

How to read this chart

60‑month range $22.69 – $80.67 · fair‑value band $60.75 – $111.29 · the $27.00 price screens below the $81.00 fair value. Dashed = 300-day average. As of Jul 24, 2026.

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Analysis

Lakefront Biotherapeutics NV (LKFT) currently trades at $27.00, while our model-based Fair Value estimate is $81.00, implying the stock looks roughly 200.0% undervalued today. The Quality Score stands at 70/100 (solid quality), in the Healthcare sector. Bull case: trading below our estimate, it may offer upside if the fundamentals hold. Bear case: a low price can be a value trap when quality is weak or the data is thin (evidence: high), always confirm before acting.

Over the trailing twelve months, Lakefront Biotherapeutics NV generated revenue of $1.0B at a net margin of 46.8%. It earns a return on equity of 16.3%. The balance sheet holds a net cash position of $81.0M. The stock trades on a trailing P/E of 3.3. Fundamentals as of Jul 24, 2026

Our scenario range runs from $60.75 (bear case) to $111.29 (bull case); at $27.00, the current price sits below that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 29% below its 52-week high and 2% above its 52-week low, currently below its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at 200%, LKFT screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Growth-Adj P/E $153.82 $219.74 $285.66 68
ROIC Compounder $63.35 $84.12 $100.93 67
P/E Multiple $73.08 $97.45 $121.81 63
All 15 models by family
DCF Models
Owner Earnings $71.55 $146.87 $286.61 31
Earnings-Based
Graham-Dodd $33.13 $231.06 $324.25 54
Lynch FV $119.37 $170.53 $221.69 50
PEG = 1.0 $119.37 $170.53 $221.69 46
EPV $56.15 $63.62 $69.85 59
Multiples
P/E Multiple $73.08 $97.45 $121.81 63
P/S Multiple $31.67 $42.22 $52.78 58
P/B Multiple $62.12 $82.83 $103.54 55
EV/EBIT $104.11 $138.37 $172.63 53
EV/EBITDA $83.83 $111.33 $138.83 54
EV/Revenue $30.89 $43.56 $56.22 43
Asset-Based
NCAV (Graham) $24.57 $32.92 $49.13 50
Economic Profit
Residual Income $40.50 $43.89 $52.65 61
ROIC Compounder $63.35 $84.12 $100.93 67
Growth Earnings
Growth-Adj P/E $153.82 $219.74 $285.66 68

Widest divergence: Growth Earnings ($219.74) versus Asset-Based ($32.92). Highest evidence: Growth-Adj P/E (68).

Key figures & financial health

Revenue (TTM) $1.0B
Revenue growth (YoY) -91.4%
Net margin 46.8%
Return on equity 16.3%
Free cash flow −$271M FY2025
P/E ratio 3.3
More key figures
Operating margin -983%
EPS (TTM) $8.60
Net cash $81.0M FY2025

Figures from reported company fundamentals · as of Jul 24, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 70/100

Of which business quality 62 · Market factors (momentum, volatility) 40

Profitability 56
Margins and returns on capital today
Quality Growth 100
Are margins and returns improving?
Cashflow 0
Earnings quality: real cash, not paper profit
Fin. Strength 82
Balance sheet, leverage, solvency risk
Investment 86
Disciplined investing over empire-building
Low Volatility 85
Calm price path (market factor)
Momentum 28
Price trend over the last 3–12 months (market factor)
52W Momentum 9
Distance to the 52-week high (market factor)
Net Issuance 82
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Lakefront Biotherapeutics NV, a biotechnology company, develops medicines focusing on oncology and immunology primarily in the United States and Europe.

Full company description

Lakefront Biotherapeutics NV, a biotechnology company, develops medicines focusing on oncology and immunology primarily in the United States and Europe. The company's pipeline products comprise GLPG3667, which is in a phase 2 clinical trial in dermatomyositis and systemic lupus erythematosus; GLPG5101, a CD19 CAR-T product candidate manufactured at point-of-care, currently in a phase 1/2 trial in relapsed/refractory non-hodgkin lymphoma; and GLPG5301, a BCMA CAR-T product candidate manufactured at point-of-care, currently in phase 1/2 in relapsed/refractory multiple myeloma. The company has collaboration agreements with Gilead Sciences, Inc. The company was formerly known as Galapagos NV and changed its name to Lakefront Biotherapeutics NV in May 2026. The company was incorporated in 1999 and is headquartered in Mechelen, Belgium.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2022 – FY2025 · reported fiscal years

Lakefront Biotherapeutics NV reported revenue of $1.1B in FY2025 versus $241M in FY2022, a compound +66.4%/yr. Reported net income was $321M in FY2025.

Growth Quality 62/100
The company is growing, but growth may require heavy reinvestment or weak cash conversion.
Latest Revenue (FY 2025)
$1.1B
Latest YoY
+303.5%
Avg. growth/yr (3Y)
+66.4%
Revenue +66.4%/yr
FY22 $241M
FY23 $240M
FY24 $276M
FY25 $1.1B
Net income
FY22 −$218M
FY23 $212M
FY24 $74.1M
FY25 $321M

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Cite: Fair Value Calculator (2026). "Lakefront Biotherapeutics NV Fair Value". https://www.fairvalue-calculator.com/stock/LKFT

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 70 · Top 25%
Fair Value upside +200% · Top 25%
Return on equity (TTM) 16% · Top 25%
Return on assets 11% · Top 25%
Net margin (TTM) 47% · Top 25%
Revenue growth -91% · Bottom 25%

Valuation Multiples vs Biotechnology median · lower = cheaper

P/E (TTM) 3.3× · Cheaper than 75% of peers
P/B 0.58× · Cheaper than 75% of peers
P/S (TTM) 1.79× · Cheaper than median
EV/EBITDA 2.7× · Cheaper than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 100 · sector 0
FUTURE 0 · sector 0
PAST 65 · sector 0
HEALTH 0 · sector 97
DIVIDEND 0 · sector 23

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 24, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is Lakefront Biotherapeutics NV (LKFT) overvalued or undervalued?
As of Jul 24, 2026, our model estimates a fair value of $81.00 versus a price of $27.00, about +200% (undervalued).
What is the fair value of LKFT?
Our model-based fair value for Lakefront Biotherapeutics NV is $81.00 (as of Jul 24, 2026), built from audited fundamentals. The current price is $27.00.
What is the quality score of LKFT?
Lakefront Biotherapeutics NV has a Quality Score of 70/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Lakefront Biotherapeutics NV (LKFT)?
Lakefront Biotherapeutics NV reported trailing-twelve-month revenue of about $1.0B (latest available figure, as of Jul 24, 2026).
What is the net profit margin of LKFT?
The net profit margin of Lakefront Biotherapeutics NV is about 46.8%, meaning it keeps roughly 46.8% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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