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Lexicon Pharmaceuticals, Inc (LXRX) Fair Value & Analysis

Healthcare · US · Market cap $893M

LP Lexicon Pharmaceuticals, Inc logo Lexicon Pharmaceuticals, Inc LXRX · US
Price$2.47
Fair Value$2.61
Upside+5.7%
Quality48/100
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Expensive Growth
Loss-making · -37.5% net margin
Low debt · negative free cash flow
Mixed vs. peers (4/10)
Narrow moat 6/100
Evidence: Low Range $1.46 – $3.56 Share as image

Fair value as of: Jul 19, 2026

From 3 valuation models · updated 22 days ago

Share price +8.8% over the past month.

Below-average quality, currently priced close to our fair value.

What matters now

  • The price sits close to our fair value, market and models broadly agree here, little valuation tension.
  • A fairly wide model range ($1.46 to $3.56) leaves room in how you read the outcome.
  • Evidence is limited here (fewer models, shorter history), so the fair value is a rougher estimate than usual.
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Price vs Fair Value (5 years)

$6.16 $0.2926 Fair Value $2.61 Apr 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 19, 2026.

How to read this chart

60‑month range $0.2926 – $6.16 · fair‑value band $1.46 – $3.56 · the $2.47 price screens below the $2.61 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 19, 2026.

Full chart & analysis →

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Analysis

Lexicon Pharmaceuticals, Inc (LXRX) currently trades at $2.47, while our model-based Fair Value estimate is $2.61, implying the stock looks roughly 5.7% fairly valued today. The Quality Score stands at 48/100 (below-average quality), in the Healthcare sector. Bull case: trading below our estimate, it may offer upside if the fundamentals hold. Bear case: a low price can be a value trap when quality is weak or the data is thin (evidence: low), always confirm before acting.

Over the trailing twelve months, Lexicon Pharmaceuticals, Inc generated revenue of $69.6M at a net margin of -37.5%. It earns a return on equity of -16.0%. Net debt stands at $27.9M. Fundamentals as of Jul 19, 2026

Our scenario range runs from $1.46 (bear case) to $3.56 (bull case); at $2.47, the current price sits within that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 2% below its 52-week high and 242% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at 6%, LXRX screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Gordon GGM $1.75 $3.15 $4.34 70
DDM Multi-Stage $1.75 $2.88 $3.36 61
NCAV (Graham) $0.1200 $0.1600 $0.2400 50
All 3 models by family
Dividend Discount
Gordon GGM $1.75 $3.15 $4.34 70
DDM Multi-Stage $1.75 $2.88 $3.36 61
Asset-Based
NCAV (Graham) $0.1200 $0.1600 $0.2400 50

Widest divergence: Dividend Discount ($2.88) versus Asset-Based ($0.1600). Highest evidence: Gordon GGM (70).

Key figures & financial health

Revenue (TTM) $69.6M
Revenue growth (YoY) +1,572%
Net margin -37.5%
Return on equity -16.0%
Free cash flow −$67.9M FY2025
Operating margin -4.7%
More key figures
EPS (TTM) $-0.0700
EPS growth (YoY) -63.4%
Net debt $27.9M FY2025

Figures from reported company fundamentals · as of Jul 19, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 48/100

Of which business quality 46 · Market factors (momentum, volatility) 78

Profitability 12
Margins and returns on capital today
Quality Growth 93
Are margins and returns improving?
Cashflow 39
Earnings quality: real cash, not paper profit
Fin. Strength 56
Balance sheet, leverage, solvency risk
Investment 100
Disciplined investing over empire-building
Low Volatility 28
Calm price path (market factor)
Momentum 100
Price trend over the last 3–12 months (market factor)
52W Momentum 98
Distance to the 52-week high (market factor)
Net Issuance 0
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease.

Full company description

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes. It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, CKD, and other cardiovascular risk factors. In addition, the company develops LX9851, an orally-delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders, and pilavapadin (LX9211), an orally-delivered small molecule drug candidate for the treatment of neuropathic pain. It has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Lexicon Pharmaceuticals, Inc reported revenue of $49.8M in FY2025 versus $298K in FY2021, a compound +259.6%/yr. Reported net income was −$50.3M in FY2025.

Growth Quality 44/100
The company is growing, but growth may require heavy reinvestment or weak cash conversion.
Latest Revenue (FY 2025)
$49.8M
Latest YoY
+60.2%
Avg. growth/yr (3Y)
+610.3%
Avg. growth/yr (5Y)
+15.7%
Avg. growth/yr (26Y)
+9.5%
Revenue +259.6%/yr
FY21 $298K
FY22 $139K
FY23 $1.2M
FY24 $31.1M
FY25 $49.8M
Net income
FY21 −$87.8M
FY22 −$102M
FY23 −$177M
FY24 −$200M
FY25 −$50.3M

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Cite: Fair Value Calculator (2026). "Lexicon Pharmaceuticals, Inc Fair Value". https://www.fairvalue-calculator.com/stock/LXRX

Peer Group

Biotechnology · 603 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 48 · Above median
Fair Value upside +6% · Top 25%
Return on assets -5% · Above median
Net margin (TTM) -37% · Bottom 25%
Operating margin (TTM) -5% · Below median
Revenue growth 1572% · Top 25%
Debt / equity 0.46× · Higher than 75% of peers

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 8.30× · Pricier than 75% of peers
P/S (TTM) 12.82× · Pricier than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 41 · sector 0
FUTURE 100 · sector 0
PAST 0 · sector 0
HEALTH 77 · sector 97
DIVIDEND 0 · sector 23

Insider activity: 78/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 19, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is Lexicon Pharmaceuticals, Inc (LXRX) overvalued or undervalued?
As of Jul 19, 2026, our model estimates a fair value of $2.61 versus a price of $2.47, about +6% (fairly valued).
What is the fair value of LXRX?
Our model-based fair value for Lexicon Pharmaceuticals, Inc is $2.61 (as of Jul 19, 2026), built from audited fundamentals. The current price is $2.47.
What is the quality score of LXRX?
Lexicon Pharmaceuticals, Inc has a Quality Score of 48/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Lexicon Pharmaceuticals, Inc (LXRX)?
Lexicon Pharmaceuticals, Inc reported trailing-twelve-month revenue of about $69.6M (latest available figure, as of Jul 19, 2026).
What is the net profit margin of LXRX?
The net profit margin of Lexicon Pharmaceuticals, Inc is about -37.5%, meaning it is currently running at a net loss. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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