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Lexicon Pharmaceuticals Inc (LXRX) fair value: what the stock is really worth

As of Nov 10, 2026: fair value (intrinsic value) of Lexicon Pharmaceuticals Inc stock $1.24, price $1.86, that is 33.3% below the price, quality 46 out of 100. Rating: overvalued. The value is an estimate: none of our valuation models currently carries, it draws on revenue and assets compared with similar companies. Updated daily.

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Healthcare US

LP Lexicon Pharmaceuticals Inc logo Thin data Nov 10, 2026

Lexicon Pharmaceuticals Inc

LXRX · US
Expensive, weak quality

Our calculation puts a fair price 33% below what the stock costs today.

Low debt
Quality 46/100
Expensive Growth (revenue 5y +15.7 %/yr in USD)
Insiders bought $49,999 (6M)
Profit last quarter 63% below a year ago.
Fair value $1.24 · Overvalued
Loss-making · -147.4% net margin (TTM)
Negative free cash flow
Trails peers (1/9)
Narrow moat 6/100 · thin data
Thin data
Estimate
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What runs behind every stock

26 valuation models 8 families, DCF to NCAV 37 quality factors margins, balance sheet, cashflow, debt 6 AI factors moat, what no ratio measures 2,000+ data points verified, per stock, median

69 individual criteria per stock, every one traceable See the method →

Price vs Fair Value

$6.16 $0.2926 Fair Value $1.24 Aug 2021 Nov 2026

White line = price, green steps = our fair value per fiscal year. As of Nov 10, 2026.

How to read this chart

60‑month range $0.2926 – $6.16 · fair‑value band $0.9300 – $1.55 · the $1.86 price screens above the $1.24 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 10, 2026.

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Company profile

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease.

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The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes.

It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, CKD, and other cardiovascular risk factors.

In addition, the company develops LX9851, an orally-delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders, and pilavapadin (LX9211), an orally-delivered small molecule drug candidate for the treatment of neuropathic pain.

It has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.

Stock analysis

Lexicon Pharmaceuticals Inc (LXRX) currently trades at $1.86, while our estimate is $1.24, 33% below the price, so the stock looks overvalued today.

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Valuation

None of our valuation models currently carries for this company, usually because of losses or heavy investment. The estimate draws on revenue and assets compared with similar companies and is less precise than a model-based fair value.

Scenario range: $0.9300 (bear) to $1.55 (bull), the price of $1.86 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 46/100 (below-average quality), in the Healthcare sector.

Expensive Growth: The company is growing, but growth may require heavy reinvestment or weak cash conversion.

Lexicon Pharmaceuticals Inc reported revenue of $49.8M in FY2025 versus $298K in FY2021, a compound +259.6%/yr. Reported net income was −$50.3M in FY2025.

Key figures

Market cap $814M Small · P/S ratio 19.1 · EPS (TTM) $−0.1500 · Net margin −147% · Return on equity −40.2% · Return on assets (EBIT) −56.6% (5-year average) · Operating margin −3,835% · Revenue (TTM) $41.5M.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 6 out of 100 (low confidence).

What moves the price

The share trades about 30% below its 52-week high and 63% above its 52-week low, currently below its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at −7% fair-value upside, at −33%, LXRX screens richer than that median.

Fair Value

Bear $0.9300 Fair Value $1.24 Bull $1.55
Price $1.86 · Downside -33.3%
Estimate. None of our valuation models currently carries for this company, usually because of losses or heavy investment. The estimate draws on revenue and assets compared with similar companies and is less precise than a model-based fair value.

Quality Score breakdown

Overall quality 46/100

It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.

Profitability 12
How much profit the company makes from its sales and capital
Quality Growth 93
Are margins and returns getting better?
Cashflow 39
Do the profits arrive as real cash?
Financial strength 56
Debt, balance sheet and risk of trouble
Investment 100
Does it invest with discipline instead of growing at any price?
Low Volatility 28
How calm the share price moves, does not count
Price momentum 35
Price momentum of the last 3 to 12 months, does not count
Near the 52-week high 68
Distance to the 52-week high, does not count
New shares 0
Buys back shares or issues new ones?

Open the full quality analysis →

Insider trades

In the last 6 months, one officer or director bought shares worth $49,999, on Nov 6, 2026.

  • BuyMichael ExtonChief Executive Officer, Director30,064 shares at $1.66$49,999Nov 6, 2026
  • BuyRaymond DebbaneDirector4× since Feb 13, 2026: 520,497 shares, avg. $1.39$723,048Feb 25, 2026
  • BuyArtal Group S.A.Director, 10% owner1,538,462 shares at $1.30$2.0MFeb 2, 2026

Plus 7 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.

Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.

Source: SEC Form 4, as of Nov 10, 2026. All filings at the SEC ↗

Revenue & earnings trend

Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card. 44/100
The company is growing, but growth may require heavy reinvestment or weak cash conversion.
Revenue growth 1 year
+60.2%
Revenue growth 3 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+610.3%
Revenue growth 5 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+15.7%
Start year 2020 (pandemic). Over 10 years: −9.1% a year
Revenue growth 26 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+9.5%
Profit margin (trend) ⓘOperating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−199.2% (2020) → −98.2% (2025)
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

LXRX screens overvalued: fair value 33% below the price. Compare with Vertex Pharmaceuticals Incorporated →

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 849 stocks

Beats the industry median on 1/8 measures
Overall it trails its industry peers.
Valuation
Quality Score 46 · Above median
Fair Value upside −33.3% · Below median
Profitability
Return on assets −27.2% · Below median
Net margin (12 months) −147.4% · Bottom 25%
Growth and dividend
Revenue growth (quarter YoY) −97.6% · Bottom 25%
Balance sheet
Debt / equity 0.46× · Highest 25%

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/B 7.57× · Priciest 25%
P/S (12 months) 19.63× · Priciest 25%

Strength profile in five axes (Snowflake)

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE (fair-value potential)0 · sector 0
FUTURE (revenue growth)0 · sector 0
PAST (return on equity)0 · sector 0
HEALTH (low debt)77 · sector 96
DIVIDEND (yield)0 · sector 20

VALUE 0: the price sits above our fair-value range.

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value Compare
Regeneron Pharmaceuticals, Inc REGN $916.06 $1,275 +39% vs LXRX
Samsung Biologics Co 207940 1,468,000 KRW 1,661,000 KRW +13% vs LXRX
Vertex Pharmaceuticals Incorporated VRTX $547.89 $601.80 +10% vs LXRX
Genmab A/S GMAB kr 3,581 kr 3,880 +8% vs LXRX
argenx SE ARGX $971.55 $908.40 −7% vs LXRX
CSL Limited CSL A$201.68 A$181.40 −10% vs LXRX
Moderna, Inc MRNA $250.83 $158.70 −37% vs LXRX
BeOne Medicines AG 6160 HK$252.20 HK$152.80 −39% vs LXRX
Celltrion, Inc 068270 203,000 KRW 74,945 KRW −63% vs LXRX
Royalty Pharma plc RPRX $69.45 $19.01 −73% vs LXRX

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Lexicon Pharmaceuticals Inc: fair value per Fair Value Calculator

Cite: Fair Value Calculator (2026). "Lexicon Pharmaceuticals Inc Fair Value". https://www.fairvalue-calculator.com/stock/LXRX

Frequently asked questions

Is Lexicon Pharmaceuticals Inc (LXRX) overvalued or undervalued?
As of Nov 10, 2026, our estimate of fair value is $1.24 versus a price of $1.86, about 33% lower (overvalued).
What is the fair value of LXRX?
Our estimate for Lexicon Pharmaceuticals Inc is $1.24 (as of Nov 10, 2026), built from audited fundamentals. The current price: $1.86.
What is the quality score of LXRX?
Lexicon Pharmaceuticals Inc has a Quality Score of 46/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Lexicon Pharmaceuticals Inc (LXRX)?
Our calculated price target is the estimate of $1.24 (as of Nov 10, 2026). Cautious scenario $0.9300, optimistic scenario $1.55. It is an estimate from revenue and assets compared with similar companies, because none of our valuation models currently carries, not an analyst target.
What is the Lexicon Pharmaceuticals Inc stock forecast for 2026?
Our estimate puts fair value at $1.24, about 33% lower versus a price of $1.86 (overvalued). Cautious scenario $0.9300, optimistic scenario $1.55. The calculation is refreshed regularly with new filings.
What is the revenue of Lexicon Pharmaceuticals Inc (LXRX)?
Lexicon Pharmaceuticals Inc reported trailing-twelve-month revenue of about $41.5M (latest available figure, as of Nov 10, 2026).
What is the intrinsic value of Lexicon Pharmaceuticals Inc (LXRX)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Lexicon Pharmaceuticals Inc it is $1.24 per share (as of Nov 10, 2026), against a price of $1.86.
Is Lexicon Pharmaceuticals Inc stock overvalued or undervalued in 2026?
As of Nov 10, 2026, LXRX trades above its calculated fair value: price $1.86, fair value $1.24, a gap of about −33% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of LXRX?
No. The price is what the market pays today ($1.86); the fair value is what the company's own numbers justify ($1.24). For Lexicon Pharmaceuticals Inc the two are $0.6200 per share apart. That gap is exactly why we show both numbers side by side.
How much is Lexicon Pharmaceuticals Inc worth?
The market values Lexicon Pharmaceuticals Inc at about $814M (market capitalisation, as of Nov 10, 2026). Per share that is $1.86; our models calculate a fair value of $1.24 per share.
What do the bullish and bearish scenarios say about LXRX?
Our models span a range for Lexicon Pharmaceuticals Inc: cautious scenario $0.9300, base $1.24, optimistic $1.55 per share (as of Nov 10, 2026, price $1.86). The range comes from different growth and margin assumptions, not from analyst opinions.
How solid is the balance sheet of Lexicon Pharmaceuticals Inc (LXRX)?
Balance-sheet figures for Lexicon Pharmaceuticals Inc (as of Nov 10, 2026): return on equity −40.2%, debt of 0.46 per unit of equity. They feed the Quality Score of 46/100, which measures business quality independently of the share price.
How far is LXRX from its 52-week high?
Lexicon Pharmaceuticals Inc trades at $1.86, about 30% below its 52-week high of $2.64 and 63% above the low of $1.14 (as of Nov 10, 2026). Distance from the high says nothing about value: that is what the fair value of $1.24 is for.
Which stocks are comparable to Lexicon Pharmaceuticals Inc?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Moderna, Inc, Regeneron Pharmaceuticals, Inc, CSL Limited, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Lexicon Pharmaceuticals Inc stock attractive at the current price?
The data as of Nov 10, 2026: price $1.86, calculated fair value $1.24 (−33%), Quality Score 46/100. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
Is it still worth investing in stocks now?
The global stock market currently sits 15.1% above its aggregate fair value. Lexicon Pharmaceuticals Inc itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Lexicon Pharmaceuticals Inc (LXRX)?
The closing price on Nov 10, 2026 was $1.86. Our estimate is $1.24, about 33% lower (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Lexicon Pharmaceuticals Inc right now?
The price sits above even our optimistic bull case ($1.55). The favourable scenario is already priced in. Weak quality (46/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.

Key figures of Lexicon Pharmaceuticals Inc

How large is the market capitalisation of Lexicon Pharmaceuticals Inc (LXRX)?
The market capitalisation of Lexicon Pharmaceuticals Inc is $814M. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What is the P/S ratio of Lexicon Pharmaceuticals Inc (LXRX)?
The price-to-sales ratio of Lexicon Pharmaceuticals Inc is 19.1 (last twelve months). Price to sales: market value relative to yearly revenue. Useful when profit is thin or distorted.
What are the earnings per share of Lexicon Pharmaceuticals Inc (LXRX)?
Earnings per share at Lexicon Pharmaceuticals Inc are $−0.1500. Earnings per share over the last twelve months: total profit spread across every single share.
What is the net margin of Lexicon Pharmaceuticals Inc (LXRX)?
The net margin of Lexicon Pharmaceuticals Inc is −147% (last twelve months). How much of every unit of revenue ends up as profit. 10% means 10 cents of profit per dollar of sales.
What is the return on equity of Lexicon Pharmaceuticals Inc (LXRX)?
The return on equity (ROE) of Lexicon Pharmaceuticals Inc is −40.2% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Lexicon Pharmaceuticals Inc (LXRX)?
On an EBIT basis the return on assets of Lexicon Pharmaceuticals Inc is −56.6% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
What is the operating margin of Lexicon Pharmaceuticals Inc (LXRX)?
The operating margin of Lexicon Pharmaceuticals Inc is −3,835% (last twelve months). Profit from the core business (before interest and taxes) relative to revenue.
How fast is revenue growing at Lexicon Pharmaceuticals Inc (LXRX)?
Revenue at Lexicon Pharmaceuticals Inc is growing −97.6% versus a year earlier (3y avg +610%). How much revenue grew versus a year earlier (YoY). The 3-year average next to it puts the single year in context.
How fast are earnings growing at Lexicon Pharmaceuticals Inc (LXRX)?
Earnings per share at Lexicon Pharmaceuticals Inc are growing −63.4% versus a year earlier. How much earnings per share grew versus a year earlier.
How much free cash flow does Lexicon Pharmaceuticals Inc (LXRX) generate?
The free cash flow of Lexicon Pharmaceuticals Inc is −$67.9M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net debt does Lexicon Pharmaceuticals Inc (LXRX) carry?
The net debt of Lexicon Pharmaceuticals Inc is $27.9M (fiscal year 2025). Debt minus cash on hand. The note shows how many years of free cash flow could in theory pay it off.
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