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Milestone Pharmaceuticals Inc (MIST) fair value: what the stock is really worth

As of Sep 24, 2026: fair value of Milestone Pharmaceuticals Inc $0.27, price $0.79, upside -65.8%, quality 20 out of 100. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.

  1. Fair value above price? No
  2. Good quality? No
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Healthcare · US · Home Canada · ISIN CA59935V1076

MP Milestone Pharmaceuticals Inc logo Thin data Sep 24, 2026

Milestone Pharmaceuticals Inc

MIST · US

Weakest SetupStrongly overvalued and low quality.

!Fair value $0.2720 · Strongly overvalued (−66%)
!Quality 20/100
!Weak Growth (revenue 5y −36.5 %/yr)
!Moderate debt · negative free cash flow
!Trails peers (0/6)
!Narrow moat 12/100
!Evidence only low, so the estimate is less certain
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What runs behind every stock

26 valuation models 8 families, DCF to NCAV 37 quality factors margins, balance sheet, cashflow, debt 6 AI factors moat, what no ratio measures 2,000+ data points verified, per stock, median

69 individual criteria per stock, every one traceable See the method →

Price vs Fair Value

$9.50 $0.6530 Fair Value $0.2720 Jun 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 24, 2026.

How to read this chart

60‑month range $0.6530 – $9.50 · fair‑value band $0.1785 – $0.3400 · the $0.7949 price screens above the $0.2720 fair value. Dashed = 300-day average. As of Sep 24, 2026.

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Company profile

Milestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines in the United States and Canada.

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Milestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines in the United States and Canada. It offers CARDAMYST (etripamil) nasal spray, a prescription medication for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm in adults. The company is also developing etripamil for the indication of atrial fibrillation with rapid ventricular rate (AFib-RVR). It has a license and collaboration agreement with Corxel Pharmaceuticals to develop and commercialize etripamil. Milestone Pharmaceuticals Inc.was incorporated in 2003 and is headquartered in Montreal, Canada.

Stock analysis

Milestone Pharmaceuticals Inc (MIST) currently trades at $0.7949, while our model-based Fair Value estimate is $0.2720, implying the stock looks roughly 192.2% overvalued today.

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Valuation

How firm this estimate is: it rests on 1 models at a data quality of 96/100, which puts the evidence level at low.

Scenario range: $0.1785 (bear) to $0.3400 (bull), the price of $0.7949 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 20/100 (below-average quality), in the Healthcare sector.

Weak Growth: Revenue is shrinking: the last year, the last three and the last five years are all negative.

Milestone Pharmaceuticals Inc reported revenue of $1.5M in FY2025 versus $15.0M in FY2021, a compound −43.3%/yr. Reported net income was −$63.1M in FY2025.

Key figures

Market cap $110M · P/S ratio 47.2 · EPS (TTM) $−0.6200 · Return on equity −35,523% · Return on assets (EBIT) −61.6% · Operating margin −4,585% · Revenue (TTM) $2.3M · Free cash flow −$49.3M.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 22 out of 100 (medium confidence).

What moves the price

The share trades about 73% below its 52-week high and at its 52-week low, currently below its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at −5% fair-value upside, at −66%, MIST screens richer than that median.

Fair Value models

Bear $0.1785 Fair Value $0.2720 Bull $0.3400
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above is their evidence-weighted blend, not the output of a single model. Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence ⓘEvidence = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
Highest evidence
NCAV (Graham) $0.1700 $0.2200 $0.3400 53
All 1 models by family
Asset-Based
NCAV (Graham) $0.1700 $0.2200 $0.3400 53

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Quality Score breakdown

Overall quality 20/100

Of which business quality 22 · Market factors (momentum, volatility) 10

Profitability 1
Margins and returns on capital today
Quality Growth 51
Are margins and returns improving?
Cashflow 6
Earnings quality: real cash, not paper profit
Fin. Strength 45
Balance sheet, leverage, solvency risk
Investment 42
Disciplined investing over empire-building
Low Volatility 32
Calm price path (market factor)
Momentum 3
Price trend over the last 3–12 months (market factor)
52W Momentum 0
Distance to the 52-week high (market factor)
Net Issuance 0
Share count: buybacks or dilution?

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Revenue & earnings trend

Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card. 0/100
Revenue is shrinking: the last year, the last three and the last five years are all negative.
Revenue growth 3 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
−32.4%
Revenue growth 5 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
−36.5%
Start year 2020 (pandemic)
Profit margin (trend) ⓘOperating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−338.1% (2020) → −4,041.7% (2025)
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

MIST screens 192% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 654 stocks

Beats the industry median on 0/6 measures
Overall it trails its industry peers.
Valuation
Quality Score 22 · Bottom 25%
Fair Value upside −66% · Below median
Profitability
Return on assets −43% · Bottom 25%
Balance sheet
Debt / equity 1.37× · Highest 25%

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/B 2.64× · Pricier than median
P/S (TTM) 47.05× · Priciest 25%

Strength profile in five axes (Snowflake)

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE (fair-value potential)0 · sector 0
FUTURE (revenue growth)0 · sector 0
PAST (return on equity)0 · sector 0
HEALTH (low debt)32 · sector 97
DIVIDEND (yield)0 · sector 23

VALUE 0: the price sits above our fair-value range.

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $522.38 $574.62 +10%
Regeneron Pharmaceuticals, Inc REGN $801.82 $1,252 +56%
argenx SE ARGX $963.79 $918.60 −5%
Samsung Biologics Co 207940 1,366,000 KRW 1,502,600 KRW +10%
CSL Limited CSL A$179.12 A$197.03 +10%
Alnylam Pharmaceuticals, Inc ALNY $251.65 $218.36 −13%
Royalty Pharma plc RPRX $58.52 $24.22 −59%
BeOne Medicines AG 6160 HK$218.20 HK$169.72 −22%
Celltrion, Inc 068270 177,400 KRW 74,519 KRW −58%
BioNTech SE BNTX $100.87 $63.62 −37%

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Milestone Pharmaceuticals Inc · Fair Value
$0.2720 −192%Fair Value
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Cite: Fair Value Calculator (2026). "Milestone Pharmaceuticals Inc Fair Value". https://www.fairvalue-calculator.com/stock/MIST

Frequently asked questions

Is Milestone Pharmaceuticals Inc (MIST) overvalued or undervalued?
As of Sep 24, 2026, our model estimates a fair value of $0.2720 versus a price of $0.7949, about −66% upside (overvalued).
What is the fair value of MIST?
Our model-based fair value for Milestone Pharmaceuticals Inc is $0.2720 (as of Sep 24, 2026), built from audited fundamentals. The current price: $0.7949.
What is the quality score of MIST?
Milestone Pharmaceuticals Inc has a Quality Score of 20/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Milestone Pharmaceuticals Inc (MIST)?
Our model-based price target is the fair value of $0.2720 (as of Sep 24, 2026) from 1 valuation models. Cautious scenario $0.1785, optimistic scenario $0.3400. It is a calculation from audited fundamentals, not an analyst target.
What is the Milestone Pharmaceuticals Inc stock forecast for 2026?
Our models put fair value at $0.2720, about −66% upside versus a price of $0.7949 (overvalued). Cautious scenario $0.1785, optimistic scenario $0.3400. The calculation is refreshed regularly with new filings.
What is the revenue of Milestone Pharmaceuticals Inc (MIST)?
Milestone Pharmaceuticals Inc reported trailing-twelve-month revenue of about $2.3M (latest available figure, as of Sep 24, 2026).
What is the intrinsic value of Milestone Pharmaceuticals Inc (MIST)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Milestone Pharmaceuticals Inc it is $0.2720 per share (as of Sep 24, 2026), against a price of $0.7949. It is the blended result of 1 valuation models (cash flow, earnings, asset, dividend).
Is Milestone Pharmaceuticals Inc stock overvalued or undervalued in 2026?
As of Sep 24, 2026, MIST trades above its calculated fair value: price $0.7949, fair value $0.2720, a gap of about −66% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of MIST?
No. The price is what the market pays today ($0.7949); the fair value is what the company's own numbers justify ($0.2720). For Milestone Pharmaceuticals Inc the two are $0.5229 per share apart. That gap is exactly why we show both numbers side by side.
How much is Milestone Pharmaceuticals Inc worth?
The market values Milestone Pharmaceuticals Inc at about $110M (market capitalisation, as of Sep 24, 2026). Per share that is $0.7949; our models calculate a fair value of $0.2720 per share.
What do the bullish and bearish scenarios say about MIST?
Our models span a range for Milestone Pharmaceuticals Inc: cautious scenario $0.1785, base $0.2720, optimistic $0.3400 per share (as of Sep 24, 2026, price $0.7949). The range comes from different growth and margin assumptions, not from analyst opinions.
How solid is the balance sheet of Milestone Pharmaceuticals Inc (MIST)?
Balance-sheet figures for Milestone Pharmaceuticals Inc (as of Sep 24, 2026): debt of 1.37 per unit of equity. They feed the Quality Score of 20/100, which measures business quality independently of the share price.
How far is MIST from its 52-week high?
Milestone Pharmaceuticals Inc trades at $0.7949, about 73% below its 52-week high of $2.95 and at the low of $0.7949 (as of Sep 24, 2026). Distance from the high says nothing about value: that is what the fair value of $0.2720 is for.
Which stocks are comparable to Milestone Pharmaceuticals Inc?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, Samsung Biologics Co, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Milestone Pharmaceuticals Inc stock attractive at the current price?
The data as of Sep 24, 2026: price $0.7949, calculated fair value $0.2720 (−66%), Quality Score 20/100, from 1 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of MIST calculated?
We run Milestone Pharmaceuticals Inc through 1 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of $0.2720, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.0 % above its aggregate fair value. Milestone Pharmaceuticals Inc itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Milestone Pharmaceuticals Inc (MIST)?
The closing price on Sep 24, 2026 was $0.7949. Our model-based fair value is $0.2720, about −66% upside (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Milestone Pharmaceuticals Inc right now?
The price sits above even our optimistic bull case ($0.3400). The favourable scenario is already priced in. Weak quality (20/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution. A fairly wide model range ($0.1785 to $0.3400) leaves room in how you read the outcome.

Key figures of Milestone Pharmaceuticals Inc

How large is the market capitalisation of Milestone Pharmaceuticals Inc (MIST)?
The market capitalisation of Milestone Pharmaceuticals Inc is $110M. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What is the P/S ratio of Milestone Pharmaceuticals Inc (MIST)?
The price-to-sales ratio of Milestone Pharmaceuticals Inc is 47.2 (last twelve months). Price to sales: market value relative to yearly revenue. Useful when profit is thin or distorted.
What are the earnings per share of Milestone Pharmaceuticals Inc (MIST)?
Earnings per share at Milestone Pharmaceuticals Inc are $−0.6200. Earnings per share over the last twelve months: total profit spread across every single share.
What is the return on equity of Milestone Pharmaceuticals Inc (MIST)?
The return on equity (ROE) of Milestone Pharmaceuticals Inc is −35,523% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Milestone Pharmaceuticals Inc (MIST)?
On an EBIT basis the return on assets of Milestone Pharmaceuticals Inc is −61.6% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
What is the operating margin of Milestone Pharmaceuticals Inc (MIST)?
The operating margin of Milestone Pharmaceuticals Inc is −4,585% (last twelve months). Profit from the core business (before interest and taxes) relative to revenue.
How much free cash flow does Milestone Pharmaceuticals Inc (MIST) generate?
The free cash flow of Milestone Pharmaceuticals Inc is −$49.3M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net cash does Milestone Pharmaceuticals Inc (MIST) hold?
Milestone Pharmaceuticals Inc holds more cash than debt, $14.7M net (fiscal year 2025). The company holds more cash than debt, a safety cushion.
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