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Plus Therapeutics, Inc (PSTV) fair value: what the stock is really worth

As of Aug 7, 2026: fair value of Plus Therapeutics, Inc $0.41, price $3.84, upside -89.3%, quality 31 out of 100. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.

  1. Fair value above price? No
  2. Good quality? No
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Healthcare · US · ISIN US72941H8060

PT Plus Therapeutics, Inc logo Thin data Sep 24, 2026

Plus Therapeutics, Inc

PSTV · US

Weakest SetupStrongly overvalued and low quality.

!Fair value $0.4100 · Strongly overvalued (−89.3%)
!Quality 31/100
!Mixed Growth (revenue 5y +76.7 %/yr)
!Moderate debt · negative free cash flow
!Trails peers (1/9)
!Narrow moat 23/100
!Evidence only low, so the estimate is less certain
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What runs behind every stock

26 valuation models 8 families, DCF to NCAV 37 quality factors margins, balance sheet, cashflow, debt 6 AI factors moat, what no ratio measures 2,000+ data points verified, per stock, median

69 individual criteria per stock, every one traceable See the method →

Price vs Fair Value

$1,084 $2.92 Fair Value $0.4100 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 24, 2026.

How to read this chart

60‑month range $2.92 – $1,084 · fair‑value band $0.2700 – $0.5200 · the $3.84 price screens above the $0.4100 fair value. Dashed = 300-day average. As of Sep 24, 2026.

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Company profile

Plus Therapeutics, Inc., a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer.

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Plus Therapeutics, Inc., a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer. The company's lead radiotherapeutic candidate is rhenium obisbemeda, a patented radiotherapy for patients with central nervous system and other cancers, including recurrent glioblastoma, leptomeningeal metastases, and pediatric brain cancers. It also develops Rhenium-188 NanoLiposome Biodegradable Alginate Microsphere to treat various solid organ cancers, such as primary and secondary liver cancers by intra-arterial injection. In addition, it develops and commercializes laboratory-developed tests comprising the CNSide Test to identify tumor cells that have metastasized to the central nervous system in patients with carcinomas and melanomas. The company was formerly known as Cytori Therapeutics, Inc. and changed its name to Plus Therapeutics, Inc. in July 2019. Plus Therapeutics, Inc. was founded in 1996 and is headquartered in Houston, Texas.

Stock analysis

Plus Therapeutics, Inc (PSTV) currently trades at $3.84, while our model-based Fair Value estimate is $0.4100, 89.3% below the price, so the stock looks overvalued today.

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Valuation

How firm this estimate is: it rests on 1 models at a data quality of 96/100, which puts the evidence level at low.

Scenario range: $0.2700 (bear) to $0.5200 (bull), the price of $3.84 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 31/100 (below-average quality), in the Healthcare sector.

Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.

Plus Therapeutics, Inc reported revenue of $5.2M in FY2025 versus $0 in FY2021. Reported net income was −$22.4M in FY2025.

Key figures

Market cap $26.0M · P/E ratio 0.2 · P/S ratio 5.14 · EPS (TTM) $21.56 · Net margin −230% · Return on equity −523% · Return on assets (EBIT) −114% · Operating margin −693%.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 28 out of 100 (low confidence).

What moves the price

The share trades about 83% below its 52-week high and 31% above its 52-week low, currently below its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at 10% fair-value upside, at −89%, PSTV screens richer than that median.

Fair Value models

Bear $0.2700 Fair Value $0.4100 Bull $0.5200
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above is their evidence-weighted blend, not the output of a single model. Based on fiscal year 2025 figures (about 9 months old). Earnings retained since then ($16.30 per share) are deliberately not added. Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. If a model's bull case is above four times its base value, the table shows that limit with a > sign (like the overall Bull above): beyond it no assumption holds. Evidence ⓘEvidence = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
Highest evidence
NCAV (Graham) $0.2900 $0.3900 $0.5800 54
All 1 models by family
Asset-Based
NCAV (Graham) $0.2900 $0.3900 $0.5800 54

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Quality Score breakdown

Overall quality 31/100

Of which business quality 30 · Market factors (momentum, volatility) 6

Profitability 14
Margins and returns on capital today
Quality Growth 40
Are margins and returns improving?
Cashflow 10
Earnings quality: real cash, not paper profit
Fin. Strength 42
Balance sheet, leverage, solvency risk
Investment 100
Disciplined investing over empire-building
Low Volatility 15
Calm price path (market factor)
Momentum 2
Price trend over the last 3–12 months (market factor)
52W Momentum 2
Distance to the 52-week high (market factor)
Net Issuance 0
Share count: buybacks or dilution?

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Revenue & earnings trend

Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card. 30/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Revenue growth 1 year
−10.5%
Revenue growth 3 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+185.5%
Revenue growth 5 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+76.7%
Start year 2020 (pandemic). Over 10 years: −7.7% a year
Revenue growth 26 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+4.9%
Profit margin (trend) ⓘOperating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−3,163.0% (2020) → −293.5% (2025)
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

PSTV screens overvalued: fair value 89% below the price. Compare with Vertex Pharmaceuticals Incorporated →

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 626 stocks

Beats the industry median on 1/9 measures
Overall it trails its industry peers.
Valuation
Quality Score 30 · Bottom 25%
Fair Value upside −89.3% · Bottom 25%
Profitability
Return on assets −73.8% · Bottom 25%
Growth and dividend
Revenue growth −2.9% · Below median
Balance sheet
Debt / equity 0.95× · Highest 25%

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/E (TTM) 0.2× · Cheapest 25%
P/B 6.51× · Priciest 25%
P/S (TTM) 5.02× · Pricier than median
PEG 2.45× · Priciest 25%

Strength profile in five axes (Snowflake)

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE (fair-value potential)0 · sector 0
FUTURE (revenue growth)0 · sector 0
PAST (return on equity)0 · sector 0
HEALTH (low debt)53 · sector 97
DIVIDEND (yield)0 · sector 22

VALUE 0: the price sits above our fair-value range.

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $527.67 $580.44 +10%
Regeneron Pharmaceuticals, Inc REGN $752.25 $1,275 +69%
argenx SE ARGX $959.49 $918.60 −4%
CSL Limited CSL A$175.35 A$192.89 +10%
Samsung Biologics Co 207940 1,354,000 KRW 1,489,400 KRW +10%
BeOne Medicines AG ONC $360.85 $280.94 −22%
Alnylam Pharmaceuticals, Inc ALNY $255.96 $217.88 −15%
Royalty Pharma plc RPRX $58.21 $19.01 −67%
Celltrion, Inc 068270 177,400 KRW 74,519 KRW −58%
WuXi Biologics (Cayman) Inc 2269 HK$53.00 HK$58.30 +10%

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Plus Therapeutics, Inc · Fair Value
$0.4100 −89%Fair Value
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Cite: Fair Value Calculator (2026). "Plus Therapeutics, Inc Fair Value". https://www.fairvalue-calculator.com/stock/PSTV

Frequently asked questions

Is Plus Therapeutics, Inc (PSTV) overvalued or undervalued?
As of Sep 24, 2026, our model estimates a fair value of $0.4100 versus the last price from Aug 7, 2026 of $3.84, about −89% upside (overvalued).
What is the fair value of PSTV?
Our model-based fair value for Plus Therapeutics, Inc is $0.4100 (as of Sep 24, 2026), built from audited fundamentals. Last price (from Aug 7, 2026): $3.84.
What is the quality score of PSTV?
Plus Therapeutics, Inc has a Quality Score of 31/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Plus Therapeutics, Inc (PSTV)?
Our model-based price target is the fair value of $0.4100 (as of Sep 24, 2026) from 1 valuation models. Cautious scenario $0.2700, optimistic scenario $0.5200. It is a calculation from audited fundamentals, not an analyst target.
What is the Plus Therapeutics, Inc stock forecast for 2026?
Our models put fair value at $0.4100, about −89% upside versus the last price from Aug 7, 2026 of $3.84 (overvalued). Cautious scenario $0.2700, optimistic scenario $0.5200. The calculation is refreshed regularly with new filings.
What is the revenue of Plus Therapeutics, Inc (PSTV)?
Plus Therapeutics, Inc reported trailing-twelve-month revenue of about $5.2M (latest available figure, as of Sep 24, 2026).
What is the intrinsic value of Plus Therapeutics, Inc (PSTV)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Plus Therapeutics, Inc it is $0.4100 per share (as of Sep 24, 2026), against a price of $3.84. It is the blended result of 1 valuation models (cash flow, earnings, asset, dividend).
Is Plus Therapeutics, Inc stock overvalued or undervalued in 2026?
As of Sep 24, 2026, PSTV trades above its calculated fair value: price $3.84, fair value $0.4100, a gap of about −89% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of PSTV?
No. The price is what the market pays today ($3.84); the fair value is what the company's own numbers justify ($0.4100). For Plus Therapeutics, Inc the two are $3.43 per share apart. That gap is exactly why we show both numbers side by side.
How much is Plus Therapeutics, Inc worth?
The market values Plus Therapeutics, Inc at about $26.0M (market capitalisation, as of Sep 24, 2026). Per share that is $3.84; our models calculate a fair value of $0.4100 per share.
What do the bullish and bearish scenarios say about PSTV?
Our models span a range for Plus Therapeutics, Inc: cautious scenario $0.2700, base $0.4100, optimistic $0.5200 per share (as of Sep 24, 2026, price $3.84). The range comes from different growth and margin assumptions, not from analyst opinions.
What is the P/E ratio of PSTV?
Plus Therapeutics, Inc trades at a price-to-earnings ratio of 0.2 (as of Sep 24, 2026). A P/E on its own says little: it compares the price with ONE year of profit, while our fair value of $0.4100 is built from several models across several years. Other multiples: PEG 2.5, P/B 6.5, P/S 5.0.
What is the PEG ratio of PSTV?
The PEG ratio of Plus Therapeutics, Inc is 2.45 (P/E divided by earnings growth, as of Sep 24, 2026). That is above 1, so the growth is already paid for in the price.
How solid is the balance sheet of Plus Therapeutics, Inc (PSTV)?
Balance-sheet figures for Plus Therapeutics, Inc (as of Sep 24, 2026): debt of 0.95 per unit of equity. They feed the Quality Score of 31/100, which measures business quality independently of the share price.
How far is PSTV from its 52-week high?
Plus Therapeutics, Inc trades at $3.84, about 83% below its 52-week high of $22.24 and 31% above the low of $2.92 (as of Aug 7, 2026). Distance from the high says nothing about value: that is what the fair value of $0.4100 is for.
Which stocks are comparable to Plus Therapeutics, Inc?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, CSL Limited, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Plus Therapeutics, Inc stock attractive at the current price?
The data as of Sep 24, 2026: price $3.84, calculated fair value $0.4100 (−89%), Quality Score 31/100, from 1 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of PSTV calculated?
We run Plus Therapeutics, Inc through 1 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of $0.4100, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.5 % above its aggregate fair value. Plus Therapeutics, Inc itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Plus Therapeutics, Inc (PSTV)?
The latest price we hold is from Aug 7, 2026 and stands at $3.84. Our model-based fair value is $0.4100, about −89% upside (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Plus Therapeutics, Inc right now?
The price sits above even our optimistic bull case ($0.5200). The favourable scenario is already priced in. Weak quality (31/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution. A fairly wide model range ($0.2700 to $0.5200) leaves room in how you read the outcome.

Key figures of Plus Therapeutics, Inc

How large is the market capitalisation of Plus Therapeutics, Inc (PSTV)?
The market capitalisation of Plus Therapeutics, Inc is $26.0M. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What is the P/S ratio of Plus Therapeutics, Inc (PSTV)?
The price-to-sales ratio of Plus Therapeutics, Inc is 5.14 (last twelve months). Price to sales: market value relative to yearly revenue. Useful when profit is thin or distorted.
What are the earnings per share of Plus Therapeutics, Inc (PSTV)?
Earnings per share at Plus Therapeutics, Inc are $21.56 (price ÷ EPS = P/E 0.2). Earnings per share over the last twelve months: total profit spread across every single share.
What is the net margin of Plus Therapeutics, Inc (PSTV)?
The net margin of Plus Therapeutics, Inc is −230% (last twelve months). How much of every unit of revenue ends up as profit. 10% means 10 cents of profit per dollar of sales.
What is the return on equity of Plus Therapeutics, Inc (PSTV)?
The return on equity (ROE) of Plus Therapeutics, Inc is −523% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Plus Therapeutics, Inc (PSTV)?
On an EBIT basis the return on assets of Plus Therapeutics, Inc is −114% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
What is the operating margin of Plus Therapeutics, Inc (PSTV)?
The operating margin of Plus Therapeutics, Inc is −693% (last twelve months). Profit from the core business (before interest and taxes) relative to revenue.
How fast is revenue growing at Plus Therapeutics, Inc (PSTV)?
Revenue at Plus Therapeutics, Inc is growing −2.9% versus a year earlier (3y avg +186%). How much revenue grew versus a year earlier (YoY). The 3-year average next to it puts the single year in context.
How much free cash flow does Plus Therapeutics, Inc (PSTV) generate?
The free cash flow of Plus Therapeutics, Inc is −$20.8M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net cash does Plus Therapeutics, Inc (PSTV) hold?
Plus Therapeutics, Inc holds more cash than debt, $7.9M net (fiscal year 2025). The company holds more cash than debt, a safety cushion.
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