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Pyxis Oncology, Inc (PYXS) Fair Value & Analysis

Healthcare · US · Market cap $129M

Price$2.10
Fair Value$3.79
Upside+80.5%
Quality95/100
Evidence: Low Range $2.85 – $4.74

Fair value as of: Jun 24, 2026

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Analysis

Pyxis Oncology, Inc (PYXS) currently trades at $2.10, while our model-based Fair Value estimate is $3.79 — implying the stock looks roughly 80.5% undervalued today. We read business quality at 95/100 (high quality), in the Healthcare sector. Bull case: trading below our estimate, it may offer upside if the fundamentals hold. Bear case: a low price can be a value trap when quality is weak or the data is thin (evidence: low) — always confirm before acting.

About the company

Pyxis Oncology, Inc., a clinical stage company, engages in the development of therapeutics to treat solid tumors. Its lead antibody-drug conjugates (ADC) product candidate is PYX-201, an investigational novel ADC consisting of human immunoglobulin G1 (IgG1), which is in Phase 1 clinical trial to treat patients with relapsed or refractory solid tumors; PYX-102, an investigational immunotherapeutic targeting KLRG1, an inhibitory receptor on T cells and NK cells, with potential for use as monotherapy or in combination treatments; and lead immuno-oncology (IO) product candidate is PYX-106, an investigational fully human IgG1 Siglec-15-targeting antibody that is in Phase 1 clinical trial to treat patients with advanced solid tumors. The company is also developing PYX-107, a CD40 agonist with demonstrated anti-cancer activity in patients with several cancer indications, which is in Phase 2 clinical trial for the treatment of tumors, such as soft tissue sarcomas, esophageal and gastroesoph…

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Frequently asked questions

Is Pyxis Oncology, Inc (PYXS) undervalued?
As of Jun 24, 2026, our model estimates a fair value of $3.79 versus a price of $2.10 — about +80% (undervalued). Model-based estimate, not financial advice.
What is the fair value of PYXS?
Our 21-model fair value for Pyxis Oncology, Inc is $3.79 (as of Jun 24, 2026), built from audited fundamentals. The current price is $2.10.
What is the quality score of PYXS?
Pyxis Oncology, Inc has a Quality Score of 95/100, measuring profitability, growth and balance-sheet strength from non-valuation factors.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data — nothing guessed.

Educational research only · not financial advice · no buy/sell recommendation. Model-based estimates are not certainties; their reliability depends on data quality and assumptions.