Ono Pharmaceutical Co Ltd (OPHLY) fair value: what the stock is really worth
As of Nov 6, 2026: fair value (intrinsic value) of Ono Pharmaceutical Co Ltd stock $7.86, price $4.91, upside +60.0%, quality 80 out of 100. Rating: strongly undervalued. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.
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Ono Pharmaceutical Co Ltd
OPHLY · USThe stock costs 38% less than our calculation considers fair.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 6, 2026.
How to read this chart
60‑month range $2.94 – $7.64 · fair‑value band $5.89 – $9.82 · the $4.91 price screens below the $7.86 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 6, 2026.
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Company profile
Ono Pharmaceutical Co., Ltd. produces, purchases, and sells pharmaceuticals and diagnostic reagents worldwide.
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It offers Opdivo intravenous infusion and Kyprolis intravenous injection for malignant tumors; Emend capsule intravenous injections for chemotherapy-induced nausea and vomiting; Demser capsules for the symptoms in patients with pheochromocytoma; Mektovi, Velexbru, and Braftovi capsules for malignant tumors; and ADLUMIZ tablets for cancer cachexia.
The company also provides Glactiv tablets for type 2 diabetes; Forxiga tablets for diabetes, chronic heart failure, and chronic kidney disease; Onoact intravenous infusion for tachyarrhythmia; Opalmon tablets to treat peripheral circulatory disorder; Coralan for chronic heart failure; Orencia injections for rheumatoid arthritis; Rivastach patches for Alzheimer's disease; Ongentys tablets for Parkinson's disease; Parsabiv for the treatment of secondary hyperparathyroidism; Staybla tablets for overactive bladder; Onon capsules and Dry Syrups for bronchial asthma and allergic rhinitis; and Joyclu intra-articular injection for the improvement of joint function, as well as Recalbon tablets for osteoporosis.
In addition, it develops products for hepatocellular and urothelial carcinoma; ovarian, bladder, prostate, pancreatic, gastric, esophageal, colorectal, thyroid, cell lung, and breast cancer; acute myeloid leukemia; solid tumors; myelodysplastic syndrome; melanoma; T-cell lymphoma; tachyarrhythmia; pemphigus; scleroderma; seizures; diabetic polyneuropathy; neurodegenerative diseases; autoimmune diseases; narcolepsy; and thrombosis.
The company has collaborations with Adimab LLC; Turbine Ltd.; Harvard University; Sibylla Biotech; and Congruence Therapeutics. Ono Pharmaceutical Co., Ltd. was founded in 1717 and is headquartered in Osaka, Japan.
Stock analysis
Ono Pharmaceutical Co Ltd (OPHLY) currently trades at $4.91, while our model-based Fair Value estimate is $7.86, implying the stock looks roughly 38% undervalued today.
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Valuation
Bull case: the Growth DCF group reads highest at a median of $11.95 per share, and 20 of the 26 models we run sit above the $4.91 price.
Bear case: the Asset-Based group reads lowest at $0.9600, and 6 of the 26 models stay below the price. Data coverage for this calculation is medium.
Scenario range: $5.89 (bear) to $9.82 (bull), the price of $4.91 sits below it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 80/100 (high quality), in the Healthcare sector.
Healthy Growth: Revenue growth appears healthy and is supported by profitability and cash-flow quality.
Ono Pharmaceutical Co Ltd reported revenue of ¥547B in FY2026 versus ¥361B in FY2022, a compound +10.9%/yr. Reported net income was ¥74.0B in FY2026, compounding −2.1%/yr from FY2022.
Key figures
Market cap $6.9B Mid · P/E ratio 14.0 · P/S ratio 1.90 · EPS (TTM) $0.3500 · Dividend yield 3.2% · Net margin 13.5% · Return on equity 9.3% · Return on assets (EBIT) 12.7% (5-year average).
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 62 out of 100 (low confidence).
What moves the price
The share trades about 10% below its 52-week high and 26% above its 52-week low, currently below its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at −11% fair-value upside, at 60%, OPHLY screens cheaper than that median.
Fair Value models
All 26 models by family
The fair value above starts from this blend and is adjusted for a year distorted by one-off effects.
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Revenue & earnings trend
Growth Forecast
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Earlier news
- Ono Pharmaceutical Co. (OPHLF) Soars 13.9%: Is Further Upside Left in the Stock?
- Ono Pharmaceutical (TSE:4528) Could Be 58% Undervalued On First Quarter Earnings
- Are Investors Undervaluing Ono Pharmaceutical Co. (OPHLF) Right Now?
Compare Ono Pharmaceutical Co Ltd with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Drug Manufacturers - General · 74 stocks
Valuation Multiplesvs Drug Manufacturers - General median · lower = cheaper
Strength profile in five axes (Snowflake)
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
- Price/FCF by industry
- Debt-to-equity by industry
- Piotroski F-Score screener with fair value
- Undervalued stocks: US Stocks
- Valuation of the USA market
Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Drug Manufacturers - General stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| Bristol-Myers Squibb Company BMY | $62.14 | $75.91 | +22% | vs OPHLY |
| Gilead Sciences, Inc GILD | $166.89 | $183.58 | +10% | vs OPHLY |
| Amgen Inc AMGN | $460.42 | $506.31 | +10% | vs OPHLY |
| Novartis AG NOVN | CHF 133.08 | CHF 120.24 | −10% | vs OPHLY |
| AbbVie Inc ABBV | $291.31 | $259.62 | −11% | vs OPHLY |
| Merck & Co MRK | $146.73 | $129.26 | −12% | vs OPHLY |
| Pfizer Inc PFE | $29.39 | $24.87 | −15% | vs OPHLY |
| Roche Holding RO | CHF 400.00 | CHF 326.56 | −18% | vs OPHLY |
| Johnson & Johnson, JNJ | $276.22 | $168.85 | −39% | vs OPHLY |
| Eli Lilly and Company LLY | $1,354 | $749.92 | −45% | vs OPHLY |
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Key figures of Ono Pharmaceutical Co Ltd
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