Lepu Biopharma Co Ltd (2157) fair value: what the stock is really worth
As of Sep 30, 2026: fair value of Lepu Biopharma Co Ltd HK$1.79, price HK$4.24, upside -57.7%, quality 52 out of 100. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 27, 2026.
How to read this chart
55‑month range HK$2.23 – HK$25.10 · fair‑value band HK$1.34 – HK$2.24 · the HK$4.24 price screens above the HK$1.79 fair value. Dashed = 300-day average. As of Sep 27, 2026.
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Lepu Biopharma Co., Ltd., a biopharmaceutical company, focuses on the discovery, development, and commercialization of drug candidates in anti-tumor targeted therapy and oncology immunotherapy in China and internationally.
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Lepu Biopharma Co., Ltd., a biopharmaceutical company, focuses on the discovery, development, and commercialization of drug candidates in anti-tumor targeted therapy and oncology immunotherapy in China and internationally. The company offers PUYOUHENG (Pucotenlimab Injection), a humanized IgG4 mAb against human PD-1 for the treatment of MSI-H/dMMR solid tumors solid tumors and melanoma. It is also developing MRG003 that is in phase III clinical study for treating nasopharyngeal cancer, and head and neck squamous cell carcinoma; CMG901 CLDN18.2-targeted ADC, which is in phase III trials for treating gastric and gastroesophageal junction carcinoma and other solid tumors; and MRG004A TF-targeted ADC, which is in phase III clinical trial for treating pancreatic ductal adenocarcinoma. In addition, the company is developing CG00705 Oncolytic virus for treating bacillus calmette-guerin unresponsive non-muscle invasive bladder cancer; and MRG002, which is in phase III trials to treat breast cancer, as well as HER2-positive. Further, the company is developing MRG001 CD20-targeted ADC for treating non-Hodgkin's lymphoma; MRG006A, MRG007, and CTM012 for the treatment of solid tumors. Lepu Biopharma Co., Ltd. was incorporated in 2018 and is headquartered in Shanghai, China. Lepu Biopharma Co., Ltd. operates as a subsidiary of Ningbo Houde Yimin Information Technology Co., Ltd.
Stock analysis
Lepu Biopharma Co Ltd (2157) currently trades at HK$4.24, while our model-based Fair Value estimate is HK$1.79, 57.7% below the price, so the stock looks overvalued today.
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Valuation
Bull case: the Growth Earnings group reads highest at a median of HK$7.66 per share, and 5 of the 15 models we run sit above the HK$4.24 price.
Bear case: the Asset-Based group reads lowest at HK$0.6000, and 10 of the 15 models stay below the price. Evidence for this calculation is low.
Scenario range: HK$1.34 (bear) to HK$2.24 (bull), the price of HK$4.24 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 52/100 (solid quality), in the Healthcare sector.
Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.
Lepu Biopharma Co Ltd reported revenue of 911M CNY in FY2025 versus 0 CNY in FY2021. Reported net income was 255M CNY in FY2025.
Key figures
Market cap HK$7.4B (≈ $947M) · P/E ratio 22.9 · P/S ratio 6.40 · EPS (TTM) HK$0.0200 · Net margin 28.0% · Return on equity 25.3% · Return on assets (EBIT) −18.1% · Operating margin −7.4%.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 50 out of 100 (low confidence).
What moves the price
The share trades about 47% below its 52-week high and 18% above its 52-week low, currently below its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at 10% fair-value upside, at −58%, 2157 screens richer than that median.
Fair Value models
Bear HK$1.34Fair Value HK$1.79Bull HK$2.24
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above is their evidence-weighted blend, not the output of a single model. Based on fiscal year 2025 figures (about 9 months old). Earnings retained since then (HK$0.0150 per share) are deliberately not added.Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. If a model's bull case is above four times its base value, the table shows that limit with a > sign (like the overall Bull above): beyond it no assumption holds.Evidence ⓘEvidence = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card.55/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Revenue growth 1 year
+147.6%
Revenue growth 3 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+288.2%
’22
’23
’24
’25
Profit margin (trend) ⓘOperating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−4,524.0% (2022) → 9.6% (2025)
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: no profitable base year
Price, fair value, quality and upside side by side.
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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 631 stocks
Beats the industry median on 6/12 measures
A mixed picture versus its industry peers.
Valuation
Quality Score52 · Above median
Fair Value upside−57.7% · Below median
Profitability
Return on equity (TTM)25.3% · Top 25%
Return on assets0.6% · Above median
Net margin (TTM)28.0% · Top 25%
Operating margin (TTM)−7.4% · Bottom 25%
Growth and dividend
Revenue growth100.0% · Top 25%
Balance sheet
Debt / equity0.20× · Above median
Valuation Multiplesvs Biotechnology median · lower = cheaper
P/E (TTM)22.9× · Cheaper than median
P/B5.36× · Priciest 25%
P/S (TTM)7.95× · Pricier than median
EV/EBITDA65.1× · Priciest 25%
Strength profile in five axes (Snowflake)
This stockSector peers
VALUE (fair-value potential)0· sector 0
FUTURE (revenue growth)100· sector 0
PAST (return on equity)100· sector 0
HEALTH (low debt)90· sector 97
DIVIDEND (yield)0· sector 22
VALUE 0: the price sits above our fair-value range.
For bloggers, editors and developers: paste this into your site or blog (a “Custom HTML” block in WordPress), it shows the current fair value and links back here. Free, plain HTML, and welcome. Full data streams (CSV/JSON) at /developers.
Cite: Fair Value Calculator (2026). "Lepu Biopharma Co Ltd Fair Value". https://www.fairvalue-calculator.com/stock/2157
Frequently asked questions
Is Lepu Biopharma Co Ltd (2157) overvalued or undervalued?
As of Sep 27, 2026, our model estimates a fair value of HK$1.79 versus a price of HK$4.24, about −58% upside (overvalued).
What is the fair value of 2157?
Our model-based fair value for Lepu Biopharma Co Ltd is HK$1.79 (as of Sep 27, 2026), built from audited fundamentals. The current price: HK$4.24.
What is the quality score of 2157?
Lepu Biopharma Co Ltd has a Quality Score of 52/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Lepu Biopharma Co Ltd (2157)?
Our model-based price target is the fair value of HK$1.79 (as of Sep 27, 2026) from 15 valuation models. Cautious scenario HK$1.34, optimistic scenario HK$2.24. It is a calculation from audited fundamentals, not an analyst target.
What is the Lepu Biopharma Co Ltd stock forecast for 2026?
Our models put fair value at HK$1.79, about −58% upside versus a price of HK$4.24 (overvalued). Cautious scenario HK$1.34, optimistic scenario HK$2.24. The calculation is refreshed regularly with new filings.
What is the revenue of Lepu Biopharma Co Ltd (2157)?
Lepu Biopharma Co Ltd reported trailing-twelve-month revenue of about HK$935M (latest available figure, as of Sep 27, 2026).
What is the intrinsic value of Lepu Biopharma Co Ltd (2157)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Lepu Biopharma Co Ltd it is HK$1.79 per share (as of Sep 27, 2026), against a price of HK$4.24. It is the blended result of 15 valuation models (cash flow, earnings, asset, dividend).
Is Lepu Biopharma Co Ltd stock overvalued or undervalued in 2026?
As of Sep 27, 2026, 2157 trades above its calculated fair value: price HK$4.24, fair value HK$1.79, a gap of about −58% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of 2157?
No. The price is what the market pays today (HK$4.24); the fair value is what the company's own numbers justify (HK$1.79). For Lepu Biopharma Co Ltd the two are HK$2.45 per share apart. That gap is exactly why we show both numbers side by side.
How much is Lepu Biopharma Co Ltd worth?
The market values Lepu Biopharma Co Ltd at about HK$7.4B (market capitalisation, as of Sep 27, 2026). Per share that is HK$4.24; our models calculate a fair value of HK$1.79 per share.
What do the bullish and bearish scenarios say about 2157?
Our models span a range for Lepu Biopharma Co Ltd: cautious scenario HK$1.34, base HK$1.79, optimistic HK$2.24 per share (as of Sep 27, 2026, price HK$4.24). The range comes from different growth and margin assumptions, not from analyst opinions.
What is the P/E ratio of 2157?
Lepu Biopharma Co Ltd trades at a price-to-earnings ratio of 22.9 (as of Sep 27, 2026). A P/E on its own says little: it compares the price with ONE year of profit, while our fair value of HK$1.79 is built from several models across several years. Other multiples: P/B 5.4, P/S 8.0, EV/EBITDA 65.1.
How solid is the balance sheet of Lepu Biopharma Co Ltd (2157)?
Balance-sheet figures for Lepu Biopharma Co Ltd (as of Sep 27, 2026): return on equity 25.3%, debt of 0.20 per unit of equity. They feed the Quality Score of 52/100, which measures business quality independently of the share price.
How far is 2157 from its 52-week high?
Lepu Biopharma Co Ltd trades at HK$4.24, about 47% below its 52-week high of HK$7.94 and 18% above the low of HK$3.58 (as of Sep 30, 2026). Distance from the high says nothing about value: that is what the fair value of HK$1.79 is for.
Which stocks are comparable to Lepu Biopharma Co Ltd?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, CSL Limited, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Lepu Biopharma Co Ltd stock attractive at the current price?
The data as of Sep 27, 2026: price HK$4.24, calculated fair value HK$1.79 (−58%), Quality Score 52/100, from 15 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of 2157 calculated?
We run Lepu Biopharma Co Ltd through 15 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of HK$1.79, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.5 % above its aggregate fair value. Lepu Biopharma Co Ltd itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Lepu Biopharma Co Ltd (2157)?
The closing price on Sep 30, 2026 was HK$4.24. Our model-based fair value is HK$1.79, about −58% upside (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Lepu Biopharma Co Ltd right now?
The price sits above even our optimistic bull case (HK$2.24). The favourable scenario is already priced in. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution. Solid but not exceptional quality (52/100) and above fair value, neither a clear bargain nor a standout compounder.
Key figures of Lepu Biopharma Co Ltd
How large is the market capitalisation of Lepu Biopharma Co Ltd (2157)?
The market capitalisation of Lepu Biopharma Co Ltd is HK$7.4B (≈ $947M). The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What is the P/S ratio of Lepu Biopharma Co Ltd (2157)?
The price-to-sales ratio of Lepu Biopharma Co Ltd is 6.40 (P/E × margin). Price to sales: market value relative to yearly revenue. Useful when profit is thin or distorted.
What are the earnings per share of Lepu Biopharma Co Ltd (2157)?
Earnings per share at Lepu Biopharma Co Ltd are HK$0.0200 (price ÷ EPS = P/E 22.9). Earnings per share over the last twelve months: total profit spread across every single share.
What is the net margin of Lepu Biopharma Co Ltd (2157)?
The net margin of Lepu Biopharma Co Ltd is 28.0% (fiscal year 2025). How much of every unit of revenue ends up as profit. 10% means 10 cents of profit per dollar of sales.
What is the return on equity of Lepu Biopharma Co Ltd (2157)?
The return on equity (ROE) of Lepu Biopharma Co Ltd is 25.3% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Lepu Biopharma Co Ltd (2157)?
On an EBIT basis the return on assets of Lepu Biopharma Co Ltd is −18.1% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
What is the operating margin of Lepu Biopharma Co Ltd (2157)?
The operating margin of Lepu Biopharma Co Ltd is −7.4% (last twelve months). Profit from the core business (before interest and taxes) relative to revenue.
How fast is revenue growing at Lepu Biopharma Co Ltd (2157)?
Revenue at Lepu Biopharma Co Ltd is growing +100% versus a year earlier (3y avg +288%). How much revenue grew versus a year earlier (YoY). The 3-year average next to it puts the single year in context.
How much free cash flow does Lepu Biopharma Co Ltd (2157) generate?
The free cash flow of Lepu Biopharma Co Ltd is −HK$82.8M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net debt does Lepu Biopharma Co Ltd (2157) carry?
The net debt of Lepu Biopharma Co Ltd is HK$205M (fiscal year 2025). Debt minus cash on hand. The note shows how many years of free cash flow could in theory pay it off.
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