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BioCryst Pharmaceuticals, Inc (BCRX) Fair Value & Analysis

Healthcare · US · Market cap $2.3B

BP BioCryst Pharmaceuticals, Inc logo BioCryst Pharmaceuticals, Inc BCRX · US
Price$9.38
Fair Value$17.33
Upside+84.8%
Quality74/100
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Mixed Growth
Loss-making · -51.7% net margin
Negative equity (buybacks among others) · generates free cash flow
Mixed vs. peers (6/11)
Narrow moat 37/100
Evidence: High Range $12.62 – $22.11 Share as image

Fair value as of: Jul 17, 2026

From 21 valuation models · updated 23 days ago

Share price −15.6% over the past month.

A solid business, screening 85% undervalued on our models.

What matters now

  • The rarer combination: high quality (74/100) AND below fair value. That earns a closer look rather than a quick verdict.
  • The price is below even our cautious bear case ($12.62). The market is more pessimistic than our downside scenario.
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Price vs Fair Value (5 years)

$19.76 $4.13 Fair Value $17.33 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 17, 2026.

How to read this chart

60‑month range $4.13 – $19.76 · fair‑value band $12.62 – $22.11 · the $9.38 price screens below the $17.33 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 17, 2026.

Full chart & analysis →

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Analysis

BioCryst Pharmaceuticals, Inc (BCRX) currently trades at $9.38, while our model-based Fair Value estimate is $17.33, implying the stock looks roughly 84.8% undervalued today. The Quality Score stands at 74/100 (solid quality), in the Healthcare sector. Bull case: trading below our estimate, it may offer upside if the fundamentals hold. Bear case: a low price can be a value trap when quality is weak or the data is thin (evidence: high), always confirm before acting.

Over the trailing twelve months, BioCryst Pharmaceuticals, Inc generated revenue of $886M at a net margin of -51.7%. Revenue grew 7.5% year over year. Net debt stands at $388M. Fundamentals as of Jul 17, 2026

Our scenario range runs from $12.62 (bear case) to $22.11 (bull case); at $9.38, the current price sits below that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 16% below its 52-week high and 56% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -49% fair-value upside, at 85%, BCRX screens cheaper than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Growth DCF $17.91 $35.30 $63.30 80
Rev-Margin DCF $11.36 $19.81 $37.61 74
ROIC Compounder $10.78 $14.29 $18.26 72
All 21 models by family
DCF Models
FCF DCF $19.16 $30.22 $64.69 38
Owner Earnings $14.02 $32.70 $70.45 31
5Y Revenue Exit $10.25 $17.13 $31.40 39
5Y EBITDA Exit $14.97 $26.68 $49.61 41
5Y P/E Exit $17.18 $39.16 $68.98 38
10Y Revenue Exit $12.80 $25.97 $33.21 36
10Y EBITDA Exit $16.48 $35.91 $69.04 37
10Y P/E Exit $18.05 $40.55 $77.18 35
Earnings-Based
Graham-Dodd $7.06 $49.23 $69.09 54
Lynch FV $25.43 $36.34 $47.24 50
PEG = 1.0 $25.43 $36.34 $47.24 46
EPV $9.65 $11.38 $12.88 59
Multiples
P/E Multiple $17.13 $22.84 $28.55 63
P/S Multiple $9.04 $12.05 $15.06 58
EV/EBIT $15.78 $21.48 $27.18 53
EV/EBITDA $12.82 $17.53 $22.25 54
EV/Revenue $5.90 $9.00 $12.10 43
Growth DCF
Growth DCF $17.91 $35.30 $63.30 80
Rev-Margin DCF $11.36 $19.81 $37.61 74
Economic Profit
ROIC Compounder $10.78 $14.29 $18.26 72
Growth Earnings
Growth-Adj P/E $33.76 $48.23 $62.70 68

Widest divergence: Growth Earnings ($48.23) versus Economic Profit ($14.29). Highest evidence: Growth DCF (80).

Key figures & financial health

Revenue (TTM) $886M
Revenue growth (YoY) +7.5%
Net margin -51.7%
Return on equity -1,925%
Free cash flow $327M FY2025
Operating margin -2.5%
More key figures
EPS (TTM) $-1.77
Net debt $388M FY2025

Figures from reported company fundamentals · as of Jul 17, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 74/100

Of which business quality 76 · Market factors (momentum, volatility) 63

Profitability 100
Margins and returns on capital today
Quality Growth 91
Are margins and returns improving?
Cashflow 88
Earnings quality: real cash, not paper profit
Fin. Strength 51
Balance sheet, leverage, solvency risk
Investment 100
Disciplined investing over empire-building
Low Volatility 64
Calm price path (market factor)
Momentum 67
Price trend over the last 3–12 months (market factor)
52W Momentum 53
Distance to the 52-week high (market factor)
Net Issuance 24
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

BioCryst Pharmaceuticals, Inc., a biotechnology company, developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases.

Full company description

BioCryst Pharmaceuticals, Inc., a biotechnology company, developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated and seasonal influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat HAE. It is also developing BCX17725, a protein therapeutic for netherton syndrome which is in phase 1; Avoralstat, an ocular plasma kallikrein inhibitor for diabetic macular edema that is in Phase 1; Navenibart, a monoclonal antibody plasma kallikrein inhibitor for HAE which is in Phase 3; BCX17725, an investigational protein therapeutic KLK5 inhibitor for the treatment of netherton syndrome that is in phase 1 clinical trial; STAR-0310, a monoclonal antibody OX40 antagonist for the treatment of atopic dermatitis which is in Phase 1a trial. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd., Shionogi & Co., Ltd., and Green Cross Corporation; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

BioCryst Pharmaceuticals, Inc reported revenue of $875M in FY2025 versus $157M in FY2021, a compound +53.6%/yr. Reported net income was $264M in FY2025.

Growth Quality 82/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$875M
Latest YoY
+94.1%
Avg. growth/yr (3Y)
+47.8%
Avg. growth/yr (31Y)
+25.9%
Revenue +53.6%/yr
FY21 $157M
FY22 $271M
FY23 $331M
FY24 $451M
FY25 $875M
Net income
FY21 −$184M
FY22 −$247M
FY23 −$227M
FY24 −$88.9M
FY25 $264M

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Cite: Fair Value Calculator (2026). "BioCryst Pharmaceuticals, Inc Fair Value". https://www.fairvalue-calculator.com/stock/BCRX

Earlier news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Drug Manufacturers - Specialty & Generic · 626 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 74 · Top 25%
Fair Value upside +85% · Top 25%
Return on assets 43% · Top 25%
Net margin (TTM) -52% · Bottom 25%
Operating margin (TTM) -2% · Bottom 25%
Revenue growth 8% · Above median

Valuation Multiples vs Drug Manufacturers - Specialty & Generic median · lower = cheaper

P/S (TTM) 2.61× · Pricier than median
P/FCF 7.1× · Pricier than median
EV/EBITDA 8.1× · Cheaper than median
PEG 9.39× · Pricier than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 100 · sector 7
FUTURE 38 · sector 20
PAST 0 · sector 23
HEALTH 100 · sector 97
DIVIDEND 0 · sector 34

PAST 0: with negative equity (buybacks among others) return on equity is not meaningfully computable.

Insider activity: 46/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Drug Manufacturers - Specialty & Generic stocks, each showing price versus our Fair Value estimate (as of Jul 17, 2026).

Stock Price Fair Value vs Fair Value
Jiangsu Hengrui Pharmaceuticals Co 600276 ¥53.19 ¥25.94 -51%
Sun Pharmaceutical Industries Limited SUNPHARMA ₹1,933 ₹989.50 -49%
Divi's Laboratories Limited DIVISLAB ₹7,316 ₹1,943 -73%
Torrent Pharmaceuticals Limited TORNTPHARM ₹4,763 ₹1,329 -72%
PharmaEssentia Corporation 6446 1,285 TWD 221.01 TWD -83%
Cipla Limited CIPLA ₹1,439 ₹1,001 -30%
Zydus Lifesciences Limited ZYDUSLIFE ₹1,151 ₹703.32 -39%
Lupin Limited LUPIN ₹2,443 ₹2,477 +1%
Mankind Pharma Limited MANKIND ₹2,484 ₹983.11 -60%
Dr. Reddy's Laboratories Limited DRREDDY ₹1,211 ₹874.79 -28%

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Frequently asked questions

Is BioCryst Pharmaceuticals, Inc (BCRX) overvalued or undervalued?
As of Jul 17, 2026, our model estimates a fair value of $17.33 versus a price of $9.38, about +85% (undervalued).
What is the fair value of BCRX?
Our model-based fair value for BioCryst Pharmaceuticals, Inc is $17.33 (as of Jul 17, 2026), built from audited fundamentals. The current price is $9.38.
What is the quality score of BCRX?
BioCryst Pharmaceuticals, Inc has a Quality Score of 74/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of BioCryst Pharmaceuticals, Inc (BCRX)?
BioCryst Pharmaceuticals, Inc reported trailing-twelve-month revenue of about $886M (latest available figure, as of Jul 17, 2026).
What is the net profit margin of BCRX?
The net profit margin of BioCryst Pharmaceuticals, Inc is about -51.7%, meaning it is currently running at a net loss. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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