Charles River Laboratories (CRL) fair value: what the stock is really worth
As of Nov 5, 2026: fair value (intrinsic value) of Charles River Laboratories stock $121, price $313, that is 61.5% below the price, quality 60 out of 100. Rating: strongly overvalued. Calculated from audited financials with 14 of our 26 valuation models and 37 quality factors, updated daily.
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Charles River Laboratories
CRL · USOur calculation puts a fair price 61% below what the stock costs today.
What runs behind every stock
69 individual criteria per stock, every one traceable See the method →
Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 6, 2026.
How to read this chart
60‑month range $99.75 – $458.30 · fair‑value band $75.61 – $165.70 · the $313.02 price screens above the $120.66 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 6, 2026.
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Company profile
Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally.
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The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers.
This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies.
The Discovery and Safety Assessment segment offers in vitro and in vivo discovery services for the discovery, development, and safety testing of novel drugs, molecule compounds, oligonucleotides, and biotherapeutics, and antibodies through delivery of preclinical drug and therapeutic candidates ready for safety assessment; safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services; and vivarium space services.
The Manufacturing Solutions segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products; offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and contract development and manufacturing products and services.
The company has strategic collaborations with Parker Institute for Cancer Immunotherapy and Children's Hospital Los Angeles across its contract development and manufacturing organization.
Additionally, it has a strategic alliance with Francis Crick Institute (Crick), Inc. for the development of Antibody-Drug Conjugate (ADC) drug discovery and development. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.
Stock analysis
Charles River Laboratories (CRL) currently trades at $313.02, while our model-based Fair Value estimate is $120.66, 61% below the price, so the stock looks overvalued today.
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Valuation
Bull case: the DCF Models group reads highest at a median of $142.18 per share, and 0 of the 14 models we run sit above the $313.02 price.
Bear case: the Earnings-Based group reads lowest at $55.68, and 14 of the 14 models stay below the price. Data coverage for this calculation is medium.
Scenario range: $75.61 (bear) to $165.70 (bull), the price of $313.02 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 60/100 (solid quality), in the Healthcare sector.
Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.
Charles River Laboratories reported revenue of $4.0B in FY2025 versus $3.5B in FY2021, a compound +3.2%/yr. Reported net income was −$144M in FY2025.
Key figures
Market cap $15.2B Large · P/E ratio 340.2 · P/S ratio 3.82 · EPS (TTM) $0.9200 · Net margin 1.0% · Return on equity 1.3% · Return on assets (EBIT) 6.9% · Operating margin 20.6%.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 42 out of 100 (medium confidence).
What moves the price
The share trades about 17% below its 52-week high and 109% above its 52-week low, currently above its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at −8% fair-value upside, at −61%, CRL screens richer than that median.
Fair Value models
All 14 models by family
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Insider trades
In the last 6 months, 6 officers or directors sold shares worth $52.1M and none bought.
- SaleJames C FosterDirector4× since Jun 29, 2026: 161,336 shares, avg. $268.13$43.3MOct 22, 202610b5-1 plan
- SaleShannon M ParisottoCEVP, Disc & Safety Assessment5× since Aug 5, 2026: 13,936 shares, avg. $287.79$4.0MOct 21, 202610b5-1 plan
- SaleNancy C AndrewsDirector573 shares at $285.24$163,443Aug 18, 2026
- SaleBirgit GirshickChief Executive Officer, Director6,500 shares at $279.90$1.8MAug 11, 202610b5-1 plan
- SaleVictoria L CreamerEVP & Chief People Officer4,179 shares at $259.16$1.1MAug 6, 2026
- SaleMichael Gunnar KnellSVP, Finance and CAO6,645 shares at $260.38$1.7MAug 6, 2026
- BuyJoseph W LaPlumeEVP, Corp Strategy & Develop25 shares at $174.54$4,364Mar 3, 2026
- Plan buyGlenn ColemanEVP & Chief Financial Officer10 shares at $297.43$2,974Sep 30, 2026
Plus 43 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.
Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.
Source: SEC Form 4, as of Nov 5, 2026. All filings at the SEC ↗
Revenue & earnings trend
Growth Forecast
CRL screens overvalued: fair value 61% below the price. Compare with Thermo Fisher Scientific Inc →
Recent news
- Charles River Laboratories Stock Pulls A Bear Move As Rats And Mice Retreat
- Bioburden Testing - Global Strategic Business Report 2026: Capture the $3.6B Market by 2032 as Becton Dickinson, Charles River, SGS, and Pac
- Charles River Q3 Earnings & Revenues Top Estimates, Stock Rises
- Charles River (CRL) Reports Q3 Earnings: What Key Metrics Have to Say
Compare Charles River Laboratories with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Diagnostics & Research · 126 stocks
Valuation Multiplesvs Diagnostics & Research median · lower = cheaper
Strength profile in five axes (Snowflake)
VALUE 0: the price sits above our fair-value range.
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
- EBIT margin by industry
- P/S ratio by industry
- Stock screener with 62 metrics
- Undervalued stocks: US Stocks
- Valuation of the USA market
Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Diagnostics & Research stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| Illumina, Inc ILMN | $208.00 | $228.80 | +10% | vs CRL |
| IQVIA Holdings IQV | $264.88 | $288.85 | +9% | vs CRL |
| WuXi AppTec Co 603259 | ¥154.46 | ¥164.66 | +7% | vs CRL |
| Thermo Fisher Scientific Inc TMO | $676.94 | $686.04 | +1% | vs CRL |
| Danaher Corporation DHR | $226.34 | $209.18 | −8% | vs CRL |
| IDEXX Laboratories, Inc IDXX | $670.71 | $496.48 | −26% | vs CRL |
| Mettler-Toledo International Inc MTD | $1,679 | $650.28 | −61% | vs CRL |
| Agilent Technologies, Inc A | $171.78 | $64.53 | −62% | vs CRL |
| Lonza Group LONN | CHF 672.40 | CHF 153.50 | −77% | vs CRL |
| Waters Corporation WAT | $453.08 | $91.26 | −80% | vs CRL |
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