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Charles River Laboratories International, Inc (CRL) Fair Value & Analysis

Healthcare · US · Market cap $11.1B

CR Charles River Laboratories International, Inc logo Charles River Laboratories International, Inc CRL · US
Price$265.51
Fair Value$120.03
Upside-54.8%
Quality62/100
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Mixed Growth
Loss-making · -4.6% net margin
Moderate debt · generates free cash flow
Trails peers (5/13)
Narrow moat 38/100
Evidence: High Range $75.22 – $164.84 Share as image

Fair value as of: Jul 16, 2026

From 15 valuation models · updated 22 days ago

Share price +16.1% over the past month.

A solid business, but screening 55% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($164.84). The favourable scenario is already priced in.
  • Solid but not exceptional quality (62/100) and above fair value, neither a clear bargain nor a standout compounder.
  • A fairly wide model range ($75.22 to $164.84) leaves room in how you read the outcome.
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Price vs Fair Value (5 years)

$458.30 $99.75 Fair Value $120.03 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 16, 2026.

How to read this chart

60‑month range $99.75 – $458.30 · fair‑value band $75.22 – $164.84 · the $265.51 price screens above the $120.03 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Jul 16, 2026.

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Analysis

Charles River Laboratories International, Inc (CRL) currently trades at $265.51, while our model-based Fair Value estimate is $120.03, implying the stock looks roughly 54.8% overvalued today. We read business quality at 62/100 (solid quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: high).

Over the trailing twelve months, Charles River Laboratories International, Inc generated revenue of $4.0B at a net margin of -4.6%. Revenue grew 1.2% year over year. It earns a return on equity of -5.9%. Net debt stands at $2.9B. Fundamentals as of Jul 16, 2026

Our scenario range runs from $75.22 (bear case) to $164.84 (bull case); at $265.51, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades near its 52-week high and 86% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -48% fair-value upside, at -55%, CRL screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model BearBaseBull Evidence
Highest evidence
Growth DCF $92.63 $180.74 $324.23 80
Rev-Margin DCF $66.68 $134.34 $218.00 74
ROIC Compounder $50.97 $66.37 $98.66 72
All 15 models by family
DCF Models
FCF DCF $92.25 $184.50 $336.65 38
5Y Revenue Exit $66.68 $134.85 $224.26 39
5Y EBITDA Exit $116.24 $233.04 $375.60 41
10Y Revenue Exit $71.25 $137.63 $232.75 36
10Y EBITDA Exit $106.71 $207.99 $354.70 37
Earnings-Based
EPV $50.97 $66.03 $79.21 59
Dividend Discount
Gordon GGM $4.88 $10.15 $16.09 70
DDM Multi-Stage $4.88 $8.55 $10.65 61
Multiples
EV/EBIT $102.93 $150.37 $197.82 53
EV/EBITDA $145.03 $206.51 $267.99 54
EV/Revenue $56.54 $97.66 $138.78 43
Asset-Based
NCAV (Graham) $32.85 $44.02 $65.70 50
Growth DCF
Growth DCF $92.63 $180.74 $324.23 80
Rev-Margin DCF $66.68 $134.34 $218.00 74
Economic Profit
ROIC Compounder $50.97 $66.37 $98.66 72

Widest divergence: DCF Models ($184.50) versus Dividend Discount ($8.55). Highest evidence: Growth DCF (80).

Key figures & financial health

Revenue (TTM) $4.0B
Revenue growth (YoY) +1.2%
Net margin -4.6%
Return on equity -5.9%
Free cash flow $518M FY2025
Operating margin 15.9%
More key figures
EPS (TTM) $-3.72
EPS growth (YoY) -17.3%
Net debt $2.9B FY2025

Figures from reported company fundamentals · as of Jul 16, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 62/100

Of which business quality 56 · Market factors (momentum, volatility) 72

Profitability 16
Margins and returns on capital today
Quality Growth 46
Are margins and returns improving?
Cashflow 62
Earnings quality: real cash, not paper profit
Fin. Strength 51
Balance sheet, leverage, solvency risk
Investment 90
Disciplined investing over empire-building
Low Volatility 30
Calm price path (market factor)
Momentum 84
Price trend over the last 3–12 months (market factor)
52W Momentum 100
Distance to the 52-week high (market factor)
Net Issuance 97
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers.

Full company description

Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies. The Discovery and Safety Assessment segment offers in vitro and in vivo discovery services for the discovery, development, and safety testing of novel drugs, molecule compounds, oligonucleotides, and biotherapeutics, and antibodies through delivery of preclinical drug and therapeutic candidates ready for safety assessment; safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services; and vivarium space services. The Manufacturing Solutions segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products; offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and contract development and manufacturing products and services. The company has strategic collaborations with Parker Institute for Cancer Immunotherapy and Children's Hospital Los Angeles across its contract development and manufacturing organization. Additionally, it has a strategic alliance with Francis Crick Institute (Crick), Inc. for the development of Antibody-Drug Conjugate (ADC) drug discovery and development. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Charles River Laboratories International, Inc reported revenue of $4.0B in FY2025 versus $3.5B in FY2021, a compound +3.2%/yr. Reported net income was −$144M in FY2025.

Growth Quality 43/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$4.0B
Latest YoY
−0.9%
Avg. growth/yr (3Y)
+0.3%
Avg. growth/yr (5Y)
+6.5%
Avg. growth/yr (27Y)
+11.9%
Revenue +3.2%/yr
FY21 $3.5B
FY22 $4.0B
FY23 $4.1B
FY24 $4.0B
FY25 $4.0B
Net income
FY21 $391M
FY22 $486M
FY23 $475M
FY24 $10.3M
FY25 −$144M

CRL screens 55% overvalued. Compare with Thermo Fisher Scientific Inc →

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Cite: Fair Value Calculator (2026). "Charles River Laboratories International, Inc Fair Value". https://www.fairvalue-calculator.com/stock/CRL

Recent news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Diagnostics & Research · 137 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 62 · Top 25%
Fair Value upside −55% · Below median
Return on assets 4% · Above median
Net margin (TTM) -5% · Below median
Operating margin (TTM) 16% · Above median
Revenue growth 1% · Below median
Debt / equity 0.67× · Higher than 75% of peers

Valuation Multiples vs Diagnostics & Research median · lower = cheaper

P/B 3.52× · Pricier than median
P/S (TTM) 2.77× · Pricier than median
P/FCF 21.5× · Pricier than median
EV/EBITDA 14.7× · Cheaper than median
PEG 0.12× · Cheaper than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 0 · sector 0
FUTURE 6 · sector 29
PAST 0 · sector 11
HEALTH 67 · sector 96
DIVIDEND 0 · sector 21

VALUE 0: the price sits above our fair-value range.

Insider activity: 45/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Diagnostics & Research stocks, each showing price versus our Fair Value estimate (as of Jul 16, 2026).

Stock Price Fair Value vs Fair Value
Thermo Fisher Scientific Inc TMO $543.19 $308.19 -43%
Danaher Corporation DHR $199.66 $103.88 -48%
WuXi AppTec Co 2359 HK$160.70 HK$125.20 -22%
Lonza Group LONN CHF 567.80 CHF 259.80 -54%
IDEXX Laboratories, Inc IDXX $567.44 $255.77 -55%
Agilent Technologies, Inc A $131.46 $62.70 -52%
Waters Corporation WAT $368.98 $121.96 -67%
IQVIA Holdings IQV $207.85 $134.18 -35%
Integrated Diagnostics Holdings IDHC $0.0050 $0.0053 +5%
Illumina, Inc ILMN $186.65 $95.51 -49%

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Frequently asked questions

Is Charles River Laboratories International, Inc (CRL) overvalued or undervalued?
As of Jul 16, 2026, our model estimates a fair value of $120.03 versus a price of $265.51, about −55% (overvalued).
What is the fair value of CRL?
Our model-based fair value for Charles River Laboratories International, Inc is $120.03 (as of Jul 16, 2026), built from audited fundamentals. The current price is $265.51.
What is the quality score of CRL?
Charles River Laboratories International, Inc has a Quality Score of 62/100. It combines two groups: business quality (profitability, growth, cash flow, balance-sheet strength) and market factors (price momentum, distance to the 52-week high, volatility). Both subtotals are shown separately in the detail view.
What is the revenue of Charles River Laboratories International, Inc (CRL)?
Charles River Laboratories International, Inc reported trailing-twelve-month revenue of about $4.0B (latest available figure, as of Jul 16, 2026).
What is the net profit margin of CRL?
The net profit margin of Charles River Laboratories International, Inc is about -4.6%, meaning it is currently running at a net loss. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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