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Edgewise Therapeutics Inc (EWTX) fair value: what the stock is really worth

As of Oct 2, 2026: fair value of Edgewise Therapeutics Inc $4.72, price $41.40, upside -88.6%, quality 26 out of 100. Calculated from audited financials with 26 valuation models and 37 quality factors, updated daily.

  1. Fair value above price? No
  2. Good quality? No
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Healthcare · US · ISIN US28036F1057

ET Edgewise Therapeutics Inc logo Thin data Sep 24, 2026

Edgewise Therapeutics Inc

EWTX · US

Weakest SetupStrongly overvalued and low quality.

!Fair value $4.72 · Strongly overvalued (−88.6%)
!Quality 26/100
!negative free cash flow
!Trails peers (2/7)
!Narrow moat 8/100
!Insider activity 46/100
!Evidence only low, so the estimate is less certain

What runs behind every stock

69 individual criteria per stock, every one traceable See the method →

Price vs Fair Value

$48.35 $5.51 Fair Value $4.72 Jul 2021 Oct 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 24, 2026.

How to read this chart

60‑month range $5.51 – $48.35 · fair‑value band $3.12 – $5.90 · the $41.40 price screens above the $4.72 fair value. Dashed = 300-day average. As of Sep 24, 2026.

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Company profile

Edgewise Therapeutics, Inc., a biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of muscle disorders.

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Edgewise Therapeutics, Inc., a biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of muscle disorders. Its lead product candidate, sevasemten, an orally administered small molecule that is in Phase II clinical trials, designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy. The company develops EDG-7500, a small molecule for the treatment of hypertrophic cardiomyopathy and other severe cardiac disorders that is in Phase I clinical trials; and EDG-15400, a novel small molecule for the treatment of heart failure with preserved ejection fraction. In addition, it develops a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address genetically defined muscle disorders. The company was incorporated in 2017 and is headquartered in Boulder, Colorado.

Stock analysis

Edgewise Therapeutics Inc (EWTX) currently trades at $41.40, while our model-based Fair Value estimate is $4.72, 88.6% below the price, so the stock looks overvalued today.

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Valuation

How firm this estimate is: it rests on 1 models at a data quality of 96/100, which puts the evidence level at low.

Scenario range: $3.12 (bear) to $5.90 (bull), the price of $41.40 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 26/100 (below-average quality), in the Healthcare sector.

Edgewise Therapeutics Inc reported revenue of $0 in FY2025 versus $0 in FY2021. Reported net income was −$168M in FY2025.

Key figures

Market cap $4.5B · EPS (TTM) $−1.83 · Return on equity −38.0% · Return on assets (EBIT) −24.4% · Free cash flow −$144M · Net cash $57.2M.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 32 out of 100 (low confidence).

What moves the price

The share trades about 14% below its 52-week high and 182% above its 52-week low, currently above its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at 10% fair-value upside, at −89%, EWTX screens richer than that median.

Fair Value models

Bear $3.12 Fair Value $4.72 Bull $5.90
Model ⓘEach model values the company its own way (discounted cash flow, earnings, assets, dividends). The fair value above is their evidence-weighted blend, not the output of a single model. Bear ⓘBear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull ⓘBull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. If a model's bull case is above four times its base value, the table shows that limit with a > sign (like the overall Bull above): beyond it no assumption holds. Evidence ⓘEvidence = how well-backed THIS model's estimate is for this stock (0–100): how complete and reliable its input data are, and how well the model fits the company. The final Fair Value is an evidence-weighted blend, so better-evidenced models count more. Green ≥70, amber 50–69, grey below 50.
Highest evidence
NCAV (Graham) $2.40 $3.22 $4.81 51
All 1 models by family
Asset-Based
NCAV (Graham) $2.40 $3.22 $4.81 51

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Quality Score breakdown

Overall quality 26/100

Of which business quality 32 · Market factors (momentum, volatility) 71

Profitability 0
Margins and returns on capital today
Quality Growth 36
Are margins and returns improving?
Cashflow 24
Earnings quality: real cash, not paper profit
Fin. Strength 84
Balance sheet, leverage, solvency risk
Investment 27
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 74
Price trend over the last 3–12 months (market factor)
52W Momentum 90
Distance to the 52-week high (market factor)
Net Issuance 17
Share count: buybacks or dilution?

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Revenue & earnings trend

What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

EWTX screens overvalued: fair value 89% below the price. Compare with Vertex Pharmaceuticals Incorporated →

Recent news

News mood ⓘNews mood, the average tone of recent news (83 articles), rated against how stocks are usually covered. 🚀 Hype = unusually upbeat · 🙂 Positive = above average · 😐 Neutral = typical · 🙁 Negative = below average · 😨 Very negative = unusually downbeat. It reflects the tone of coverage, not our valuation. Positive
Recent news coverage is more positive than average.

Compare Edgewise Therapeutics Inc with another stock

Price, fair value, quality and upside side by side.

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 625 stocks

Beats the industry median on 2/6 measures
Overall it trails its industry peers.
Valuation
Quality Score 32 · Bottom 25%
Fair Value upside −88.3% · Bottom 25%
Profitability
Return on assets −25.0% · Below median
Operating margin (TTM) 0.0% · Above median
Growth and dividend
Revenue growth 0.0% · Above median

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/B 9.19× · Priciest 25%

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $527.67 $580.44 +10%
Regeneron Pharmaceuticals, Inc REGN $752.25 $1,275 +69%
argenx SE ARGX $959.49 $918.60 −4%
CSL Limited CSL A$175.35 A$192.89 +10%
Samsung Biologics Co 207940 1,354,000 KRW 1,489,400 KRW +10%
BeOne Medicines AG ONC $360.85 $280.94 −22%
Alnylam Pharmaceuticals, Inc ALNY $255.96 $217.88 −15%
Royalty Pharma plc RPRX $58.21 $19.01 −67%
Celltrion, Inc 068270 177,400 KRW 74,519 KRW −58%
WuXi Biologics (Cayman) Inc 2269 HK$53.00 HK$58.30 +10%

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Cite: Fair Value Calculator (2026). "Edgewise Therapeutics Inc Fair Value". https://www.fairvalue-calculator.com/stock/EWTX

Frequently asked questions

Is Edgewise Therapeutics Inc (EWTX) overvalued or undervalued?
As of Sep 24, 2026, our model estimates a fair value of $4.72 versus a price of $41.40, about −89% upside (overvalued).
What is the fair value of EWTX?
Our model-based fair value for Edgewise Therapeutics Inc is $4.72 (as of Sep 24, 2026), built from audited fundamentals. The current price: $41.40.
What is the quality score of EWTX?
Edgewise Therapeutics Inc has a Quality Score of 26/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Edgewise Therapeutics Inc (EWTX)?
Our model-based price target is the fair value of $4.72 (as of Sep 24, 2026) from 1 valuation models. Cautious scenario $3.12, optimistic scenario $5.90. It is a calculation from audited fundamentals, not an analyst target.
What is the Edgewise Therapeutics Inc stock forecast for 2026?
Our models put fair value at $4.72, about −89% upside versus a price of $41.40 (overvalued). Cautious scenario $3.12, optimistic scenario $5.90. The calculation is refreshed regularly with new filings.
What is the intrinsic value of Edgewise Therapeutics Inc (EWTX)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For Edgewise Therapeutics Inc it is $4.72 per share (as of Sep 24, 2026), against a price of $41.40. It is the blended result of 1 valuation models (cash flow, earnings, asset, dividend).
Is Edgewise Therapeutics Inc stock overvalued or undervalued in 2026?
As of Sep 24, 2026, EWTX trades above its calculated fair value: price $41.40, fair value $4.72, a gap of about −89% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of EWTX?
No. The price is what the market pays today ($41.40); the fair value is what the company's own numbers justify ($4.72). For Edgewise Therapeutics Inc the two are $36.68 per share apart. That gap is exactly why we show both numbers side by side.
How much is Edgewise Therapeutics Inc worth?
The market values Edgewise Therapeutics Inc at about $4.5B (market capitalisation, as of Sep 24, 2026). Per share that is $41.40; our models calculate a fair value of $4.72 per share.
What do the bullish and bearish scenarios say about EWTX?
Our models span a range for Edgewise Therapeutics Inc: cautious scenario $3.12, base $4.72, optimistic $5.90 per share (as of Sep 24, 2026, price $41.40). The range comes from different growth and margin assumptions, not from analyst opinions.
How solid is the balance sheet of Edgewise Therapeutics Inc (EWTX)?
Balance-sheet figures for Edgewise Therapeutics Inc (as of Sep 24, 2026): return on equity −38.0%. They feed the Quality Score of 26/100, which measures business quality independently of the share price.
How far is EWTX from its 52-week high?
Edgewise Therapeutics Inc trades at $41.40, about 14% below its 52-week high of $48.35 and 182% above the low of $14.70 (as of Oct 2, 2026). Distance from the high says nothing about value: that is what the fair value of $4.72 is for.
Which stocks are comparable to Edgewise Therapeutics Inc?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Regeneron Pharmaceuticals, Inc, argenx SE, CSL Limited, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is Edgewise Therapeutics Inc stock attractive at the current price?
The data as of Sep 24, 2026: price $41.40, calculated fair value $4.72 (−89%), Quality Score 26/100, from 1 models. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
How is the fair value of EWTX calculated?
We run Edgewise Therapeutics Inc through 1 models from four families: discounted cash flow, earnings models, asset and balance-sheet models, and dividend models. Every model gets the same audited fundamentals; the result is the weighted average of $4.72, with the spread shown as a cautious and an optimistic scenario.
Is it still worth investing in stocks now?
The global stock market currently sits 14.5 % above its aggregate fair value. Edgewise Therapeutics Inc itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of Edgewise Therapeutics Inc (EWTX)?
The closing price on Oct 2, 2026 was $41.40. Our model-based fair value is $4.72, about −89% upside (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with Edgewise Therapeutics Inc right now?
The price sits above even our optimistic bull case ($5.90). The favourable scenario is already priced in. Weak quality (26/100) and above fair value at the same time, the margin of safety is missing on both counts. The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution. A fairly wide model range ($3.12 to $5.90) leaves room in how you read the outcome.

Key figures of Edgewise Therapeutics Inc

How large is the market capitalisation of Edgewise Therapeutics Inc (EWTX)?
The market capitalisation of Edgewise Therapeutics Inc is $4.5B. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What are the earnings per share of Edgewise Therapeutics Inc (EWTX)?
Earnings per share at Edgewise Therapeutics Inc are $−1.83. Earnings per share over the last twelve months: total profit spread across every single share.
What is the return on equity of Edgewise Therapeutics Inc (EWTX)?
The return on equity (ROE) of Edgewise Therapeutics Inc is −38.0% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of Edgewise Therapeutics Inc (EWTX)?
On an EBIT basis the return on assets of Edgewise Therapeutics Inc is −24.4% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
How much free cash flow does Edgewise Therapeutics Inc (EWTX) generate?
The free cash flow of Edgewise Therapeutics Inc is −$144M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net cash does Edgewise Therapeutics Inc (EWTX) hold?
Edgewise Therapeutics Inc holds more cash than debt, $57.2M net (fiscal year 2025). The company holds more cash than debt, a safety cushion.
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