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Gilead Sciences, Inc (GIS) Fair Value & Analysis

Healthcare · DE · Market cap €150B · ISIN US3755581036

What is Gilead Sciences, Inc really worth?

GS Gilead Sciences, Inc GIS · XETRA
Price€129.72
Fair Value€124.71
Upside−3.9%
Quality85/100

A strong business, currently priced close to our fair value of €124.71.

As of Sep 3, 2026, the fair value of Gilead Sciences, Inc is €124.71 per share against a price of €129.72, so the fair value sits 4% below the price. A model estimate blended from multiple valuation models, recalculated regularly.

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Strengths

Healthy Growth (revenue 5y +3.6 %/yr)
Highly profitable · 31.0% net margin
Moderate debt · generates free cash flow
Wide moat 89/100

Risks

!Trails peers (4/15)
!Weak on future: 11 out of 100
!Weak on balance sheet: 16 out of 100

For context

·2.46% dividend yield
Evidence: High Range €89.81 – €229.56

Fair value as of: Sep 3, 2026

From 26 valuation models · updated 3 days ago

Fair value updated Sep 3, 2026, revised from €123.90 to €124.71 (+0.7%) since Aug 27, 2026. Share price +15.0% over the past month.

What runs behind every stock

69 individual criteria per stock, every one traceable See the method →

What matters now

  • The price sits close to our fair value, market and models broadly agree here, little valuation tension.
  • A fairly wide model range (€89.81 to €229.56) leaves room in how you read the outcome.

Price vs Fair Value (5 years)

€129.77 €44.83 Fair Value €124.71 Jul 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Sep 3, 2026.

How to read this chart

60‑month range €44.83 – €129.77 · fair‑value band €89.81 – €229.56 · the €129.72 price screens above the €124.71 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Sep 3, 2026.

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Analysis

Gilead Sciences, Inc (GIS) currently trades at €129.72, while our model-based Fair Value estimate is €124.71, implying the stock looks roughly 4.0% fairly valued today. The Quality Score stands at 85/100 (high quality), in the Healthcare sector. Bull case: the DCF Models group reads highest at a median of €217.90 per share, and 16 of the 26 models we run sit above the €129.72 price. Bear case: the Dividend Discount group reads lowest at €51.91, and 10 of the 26 models stay below the price. Evidence for this calculation is high.

Over the trailing twelve months, Gilead Sciences, Inc generated revenue of €29.7B at a net margin of 31.0%. Revenue grew 4.4% year over year. It earns a return on equity of 43.4%. Net debt stands at €18.5B. Fundamentals as of Sep 3, 2026

Our scenario range runs from €89.81 (bear case) to €229.56 (bull case); at €129.72, the current price sits within that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 1% below its 52-week high and 47% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at −18% fair-value upside, at −4%, GIS screens cheaper than that median.

Fair Value models

This estimate rests on fiscal year 2025 figures, and about 8 months have passed since. In that time the company retained roughly €2.13 per share, which is 1.7 % of the fair value. The fair value deliberately does not add this in: the models value reported figures, not a projection.

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted, family-balanced blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small. Every input is real reported data, nothing guessed.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
FCF DCF €113.90 €189.99 €424.11 74
EPV €69.06 €82.52 €94.30 74
Growth DCF €106.93 €212.55 €422.18 74
All 26 models by family
DCF Models
FCF DCF €113.90 €189.99 €424.11 74
Owner Earnings €123.65 €296.35 €658.90 70
5Y Revenue Exit €61.17 €111.11 €209.78 69
5Y EBITDA Exit €111.83 €217.90 €416.91 71
5Y P/E Exit €104.45 €234.41 €405.08 67
10Y Revenue Exit €74.13 €151.10 €219.07 65
10Y EBITDA Exit €112.43 €251.99 €515.72 63
10Y P/E Exit €107.16 €237.30 €468.23 60
Earnings-Based
Graham-Dodd €46.61 €325.06 €456.18 63
Lynch FV €105.71 €151.01 €196.31 61
PEG = 1.0 €105.71 €151.01 €196.31 57
EPV €69.06 €82.52 €94.30 74
Dividend Discount
Gordon GGM €29.61 €61.56 €97.65 66
DDM Multi-Stage €29.61 €51.91 €64.60 66
Multiples
P/E Multiple €113.10 €150.80 €188.50 63
P/S Multiple €62.25 €83.01 €103.76 58
P/B Multiple €61.49 €81.98 €102.48 55
EV/EBIT €109.63 €150.08 €190.54 66
EV/EBITDA €111.56 €152.65 €193.75 67
EV/Revenue €38.07 €59.42 €80.76 53
Asset-Based
NCAV (Graham) €9.11 €12.21 €18.22 54
Growth DCF
Growth DCF €106.93 €212.55 €422.18 74
Rev-Margin DCF €61.17 €125.32 €223.41 69
Economic Profit
Residual Income €47.95 €64.06 €501.08 64
ROIC Compounder €89.82 €135.72 €199.51 70
Growth Earnings
Growth-Adj P/E €143.28 €204.69 €266.09 67

Widest divergence: DCF Models (€217.90) versus Asset-Based (€12.21). Highest evidence: FCF DCF (74).

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Key figures & financial health

P/E ratio 20.6
P/S ratio 5.94 P/E × margin
EPS (TTM) €6.31 price ÷ EPS = P/E 20.6
Dividend yield 2.5% payout 50.6%
Net margin 28.9% FY2025
Return on equity 43.4% TTM
More key figures
Profitability
Return on assets (EBIT) 12.3% avg 5y
Operating margin 39.3% TTM
Growth
Revenue (TTM) €29.7B TTM
Revenue growth (YoY) +4.4% 3y avg +2.6%
EPS growth (YoY) +54.8%
Balance sheet & cash flow
Free cash flow €9.5B FY2025
Net debt €18.5B FY2025 · ≈ 2.0 yrs of FCF

Figures from reported company fundamentals · as of Sep 3, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 85/100

Of which business quality 79 · Market factors (momentum, volatility) 75

Profitability 79
Margins and returns on capital today
Quality Growth 76
Are margins and returns improving?
Cashflow 86
Earnings quality: real cash, not paper profit
Fin. Strength 64
Balance sheet, leverage, solvency risk
Investment 96
Disciplined investing over empire-building
Low Volatility 90
Calm price path (market factor)
Momentum 59
Price trend over the last 3–12 months (market factor)
52W Momentum 86
Distance to the 52-week high (market factor)
Net Issuance 83
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

All values are scores from 0 to 100 (100 = best against fixed, research-based bands), not percentages. The three market factors (momentum, 52-week proximity, low volatility) are displayed but carry zero weight in the headline number: market sentiment is not a business property.

About the company

Gilead Sciences, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines in the areas of unmet medical need in the United States, Europe, and internationally. The company provides Biktarvy, Descovy, Genvoya, Odefsey, Sunlenca, Symtuza, and YeztugoFor the treatment of HIV-1 infection in patients.

Full company description

Gilead Sciences, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines in the areas of unmet medical need in the United States, Europe, and internationally. The company provides Biktarvy, Descovy, Genvoya, Odefsey, Sunlenca, Symtuza, and YeztugoFor the treatment of HIV-1 infection in patients. It also provides Epclusa, Livdelzi, and Vemlidy to treat chronic hepatitis C virus, primary biliary cholangitis, and chronic hepatitis B virus; Tecartus, a T-cell therapy for the treatment of adult patients; Trodelvy, an injection for intravenous use; and Yescarta, a suspension for intravenous infusion, is a CAR T-cell therapy for the treatment of adult patients. Further, it provides AmBisome, for the treatment of serious invasive fungal infections; and Veklury for the treatment of COVID-19. Additionally, the company engages in the development of various immunotherapies for patients with cancer and other incurable diseases. The company has collaboration agreements with Shenzhen Pregene Biopharma Co., Ltd.; Abingworth; Arcus Biosciences, Inc.; Merck Sharp & Dohme Corp.; Janssen Sciences Ireland Unlimited Company; Japan Tobacco, Inc.; Everest Medicines; Merck & Co, Inc.; Tentarix Biotherapeutics Inc.; and Assembly Biosciences, Inc. It also has research collaboration, option, and license agreement with Merus N.V. for the discovery of novel dual tumor-associated antigens (TAA) targeting trispecific antibodies. The company has a collaboration with Terray Therapeutics, Inc. to discover and develop small molecule therapies; and LEO Pharma to develop, manufacture, and commercialize the small molecule oral STAT6 program. The company was incorporated in 1987 and is headquartered in Foster City, California.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Gilead Sciences, Inc reported revenue of $29.4B in FY2025 versus $27.3B in FY2021, a compound +1.9%/yr. Reported net income was $8.5B in FY2025, compounding +8.1%/yr from FY2021.

Growth Quality 75/100
Revenue growth appears healthy and is supported by profitability and cash-flow quality.
Latest Revenue (FY 2025)
€29.4B
Latest YoY
+2.4%
Avg. revenue growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+2.6%
Avg. revenue growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+3.6%
Avg. revenue growth/yr (35Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+33.2%
Value creation/yr (5Y) Earnings growth per share (CAGR 5 years) plus dividend yield: value created per share and year.
≈ +12.5% (approximate, leans on 2025) · in EUR
Earnings growth per share plus dividend yield: the value created per share and year.
Earnings growth per share+10.0%
Dividend yield2.5%
Trend Two data points, not a trend model: earnings growth per share over the last 5 fiscal years against the last 10. Labelled "steady" when both rates are within 3 percentage points of each other, otherwise picking up or flattening. Shown only when ten years of history exist.5Y 10.0% vs 10Y −3.8%, picking up
Operating margin (EBIT) Operating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.16.5% (2020) → 40.1% (2025) · rising
Worst earnings drop98% (2020) · in EUR
⚠ Rate leans on 2025: that final year sits 86% above its own trend (e.g. a one-off disposal gain) and could not be adjusted
Revenue +1.9%/yr
FY21 $27.3B
FY22 $27.3B
FY23 $27.1B
FY24 $28.8B
FY25 $29.4B
Net income +8.1%/yr
FY21 $6.2B
FY22 $4.6B
FY23 $5.7B
FY24 $480M
FY25 $8.5B
Character of growth · EPS growth decomposed (2014-2025) −9.6 % p.a.
Revenue per share +1.7 %

of which total revenue −0.3 % · buybacks/dilution +2.1 %

EBIT margin −9.8 %
Tax rate +0.4 %
Residual (interest, one-offs) −1.8 %

Annual growth per factor. These are factors, not summands: multiplied they give the EPS growth rate, added they do not quite. Start and end points are 3-year averages (details on hover).

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Cite: Fair Value Calculator (2026). "Gilead Sciences, Inc Fair Value". https://www.fairvalue-calculator.com/stock/GIS.XETRA

Strength profile in five axes (Snowflake)

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE0 · sector 25
FUTURE11 · sector 21
PAST0 · sector 29
HEALTH16 · sector 96
DIVIDEND100 · sector 54

VALUE 0: the price sits above our fair-value range.

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Drug Manufacturers - General stocks, each showing price versus our Fair Value estimate (as of Sep 3, 2026).

Stock Price Fair Value vs Fair Value
Eli Lilly and Company LLY $1,176 $389.47 −67%
Johnson & Johnson, JNJ $275.23 $169.04 −39%
AbbVie Inc ABBV $256.46 $67.72 −74%
Roche Holding RO CHF 374.60 CHF 306.54 −18%
Merck & Co MRK €131.98 €101.38 −23%
Novartis AG NOVN CHF 123.74 CHF 114.90 −7%
Novo Nordisk A/S NOVOB kr 295.50 kr 409.46 +39%
Amgen Inc AMGN $437.23 $252.02 −42%
Pfizer Inc PFE $28.02 $24.87 −11%
Bristol-Myers Squibb Company BMY $66.58 $75.98 +14%

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Frequently asked questions

Is Gilead Sciences, Inc (GIS) overvalued or undervalued?
As of Sep 3, 2026, our model estimates a fair value of €124.71 versus a price of €129.72, about −4% upside (fairly valued).
What is the fair value of GIS?
Our model-based fair value for Gilead Sciences, Inc is €124.71 (as of Sep 3, 2026), built from audited fundamentals. The current price: €129.72.
What is the quality score of GIS?
Gilead Sciences, Inc has a Quality Score of 85/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for Gilead Sciences, Inc (GIS)?
Our model-based price target is the fair value of €124.71 (as of Sep 3, 2026) from 26 valuation models. Cautious scenario €89.81, optimistic scenario €229.56. It is a calculation from audited fundamentals, not an analyst target.
What is the Gilead Sciences, Inc stock forecast for 2026?
Our models put fair value at €124.71, about −4% upside versus a price of €129.72 (fairly valued). Cautious scenario €89.81, optimistic scenario €229.56. The calculation is refreshed regularly with new filings.
What is the revenue of Gilead Sciences, Inc (GIS)?
Gilead Sciences, Inc reported trailing-twelve-month revenue of about €29.7B (latest available figure, as of Sep 3, 2026).
What is the net profit margin of GIS?
The net profit margin of Gilead Sciences, Inc is about 31.0%, meaning it keeps roughly 31.0% of revenue as net income. Based on the latest reported figures.
Does Gilead Sciences, Inc pay a dividend?
Gilead Sciences, Inc currently shows a dividend yield of about 2.46% relative to its recent price (as of Sep 3, 2026).
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