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Maze Therapeutics, Inc (MAZE) Fair Value & Analysis

Healthcare · US · Market cap $1.4B

MT Maze Therapeutics, Inc logo Maze Therapeutics, Inc MAZE · US
Price$27.67
Fair Value$5.56
Upside-79.9%
Quality31/100
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Weak Growth
Thin margins · 0.0% net margin
negative free cash flow
Trails peers (2/9)
Narrow moat 9/100
Evidence: Low Range $3.67 – $6.95 Share as image

Fair value as of: Aug 14, 2026

From 1 valuation models · updated today

Share price −7.4% over the past month.

Below-average quality, and screening another 80% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($6.95). The favourable scenario is already priced in.
  • Weak quality (31/100) and above fair value at the same time, the margin of safety is missing on both counts.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.
  • A fairly wide model range ($3.67 to $6.95) leaves room in how you read the outcome.
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Price vs Fair Value (18 months)

$51.84 $7.57 Fair Value $5.56 Jan 2025 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Aug 14, 2026.

How to read this chart

18‑month range $7.57 – $51.84 · fair‑value band $3.67 – $6.95 · the $27.67 price screens above the $5.56 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Aug 14, 2026.

Full chart & analysis →

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Analysis

Maze Therapeutics, Inc (MAZE) currently trades at $27.67, while our model-based Fair Value estimate is $5.56, implying the stock looks roughly 79.9% overvalued today. The Quality Score stands at 31/100 (below-average quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: low).

Trailing-twelve-month revenue stands at $20.0M. It earns a return on equity of -38.7%. The balance sheet holds a net cash position of $166M. Fundamentals as of Aug 14, 2026

Our scenario range runs from $3.67 (bear case) to $6.95 (bull case); at $27.67, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 48% below its 52-week high and 181% above its 52-week low, currently below its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -47% fair-value upside, at -80%, MAZE screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
NCAV (Graham) $3.21 $4.30 $6.41 50
All 1 models by family
Asset-Based
NCAV (Graham) $3.21 $4.30 $6.41 50

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Key figures & financial health

Revenue (TTM) $20.0M
Return on equity -38.7%
Free cash flow −$113M FY2025
Operating margin -133%
EPS (TTM) $-2.35
Net cash $166M FY2025

Figures from reported company fundamentals · as of Aug 14, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 31/100

Of which business quality 38 · Market factors (momentum, volatility) 41

Profitability 0
Margins and returns on capital today
Quality Growth 0
Are margins and returns improving?
Cashflow 24
Earnings quality: real cash, not paper profit
Fin. Strength 100
Balance sheet, leverage, solvency risk
Investment 0
Disciplined investing over empire-building
Low Volatility 0
Calm price path (market factor)
Momentum 51
Price trend over the last 3–12 months (market factor)
52W Momentum 70
Distance to the 52-week high (market factor)
Net Issuance 94
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States.

Full company description

Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. Its lead programs include MZE829, an oral small molecule inhibitor of apolipoprotein L1, or APOL1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor that is in phase II ready clinical trial for the treatment of phenylketonuria and chronic kidney disease. The company also develops MZE001, an investigational oral small molecule inhibitor of muscle-specific glycogen synthase clinical program for the treatment of Pompe disease. It has a license agreement with Trace Neuroscience, Inc. to discovery research program targets UNC13A; the Shionogi & Co., Ltd to research, develop, manufacture, and commercialize MZE001; and Neurocrine Biosciences, Inc. to discover research program that targets ATXN2. The company was formerly known as Modulus Therapeutics, Inc. and changed its name to Maze Therapeutics, Inc. in September 2018. The company was incorporated in 2017 and is based in South San Francisco, California.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2022 – FY2025 · reported fiscal years

Maze Therapeutics, Inc reported revenue of $0 in FY2025 versus $0 in FY2022. Reported net income was −$131M in FY2025.

Growth Quality 0/100
Revenue growth is weak, negative or inconsistent.
Revenue
FY22 $0
FY23 $0
FY24 $168M
FY25 $0
Net income
FY22 −$115M
FY23 −$100M
FY24 $52.2M
FY25 −$131M

MAZE screens 80% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "Maze Therapeutics, Inc Fair Value". https://www.fairvalue-calculator.com/stock/MAZE

Peer Group

Biotechnology · 600 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 38 · Below median
Fair Value upside −80% · Bottom 25%
Return on assets -22% · Below median
Net margin (TTM) 0% · Above median
Operating margin (TTM) -133% · Bottom 25%
Revenue growth 0% · Above median

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 4.00× · Pricier than 75% of peers
P/S (TTM) 71.06× · Pricier than 75% of peers

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Aug 14, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $525.73 $278.78 -47%
Regeneron Pharmaceuticals, Inc REGN $797.99 $594.40 -26%
Samsung Biologics Co 207940 1,549,000 KRW 1,055,793 KRW -32%
Celltrion, Inc 068270 202,000 KRW 74,519 KRW -63%
WuXi Biologics (Cayman) Inc 2269 HK$45.70 HK$30.58 -33%
Innovent Biologics, Inc 1801 HK$95.55 HK$19.68 -79%
Genmab A/S GMAB kr 2,037 kr 250.07 -88%
Sino Biopharmaceutical Limited 1177 HK$4.87 HK$3.37 -31%
RemeGen Co 688331 ¥131.87 ¥23.19 -82%
ALTEOGEN Inc 196170 317,500 KRW 39,476 KRW -88%

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Frequently asked questions

Is Maze Therapeutics, Inc (MAZE) overvalued or undervalued?
As of Aug 14, 2026, our model estimates a fair value of $5.56 versus a price of $27.67, about −80% (overvalued).
What is the fair value of MAZE?
Our model-based fair value for Maze Therapeutics, Inc is $5.56 (as of Aug 14, 2026), built from audited fundamentals. The current price is $27.67.
What is the quality score of MAZE?
Maze Therapeutics, Inc has a Quality Score of 31/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Maze Therapeutics, Inc (MAZE)?
Maze Therapeutics, Inc reported trailing-twelve-month revenue of about $20.0M (latest available figure, as of Aug 14, 2026).
What is the net profit margin of MAZE?
The net profit margin of Maze Therapeutics, Inc is about 0.0%, meaning it keeps roughly 0.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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