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MacroGenics Inc (MGNX) fair value: what the stock is really worth

As of Nov 10, 2026: fair value (intrinsic value) of MacroGenics Inc stock $2.16, price $2.42, that is 10.7% below the price, quality 42 out of 100. Rating: overvalued. The value is an estimate: none of our valuation models currently carries, it draws on revenue and assets compared with similar companies. Updated daily.

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Healthcare US

MI MacroGenics Inc logo Thin data Nov 10, 2026

MacroGenics Inc

MGNX · US
Expensive, weak quality

Our calculation puts a fair price 11% below what the stock costs today.

Low debt
Quality 42/100
Mixed Growth (revenue 5y +8.9 %/yr in USD)
Mixed vs. peers (6/11)
Insiders sold $129,086 (6M)
Profit last quarter 70% below a year ago.
Fair value $2.16 · Overvalued
Loss-making · -8.3% net margin (TTM)
Negative free cash flow
Narrow moat 9/100
Thin data
Estimate
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What runs behind every stock

26 valuation models 8 families, DCF to NCAV 37 quality factors margins, balance sheet, cashflow, debt 6 AI factors moat, what no ratio measures 2,000+ data points verified, per stock, median

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Price vs Fair Value

$27.53 $1.06 Fair Value $2.16 Aug 2021 Nov 2026

White line = price, green steps = our fair value per fiscal year. As of Nov 10, 2026.

How to read this chart

60‑month range $1.06 – $27.53 · fair‑value band $1.62 – $2.71 · the $2.42 price screens above the $2.16 fair value. As of Nov 10, 2026.

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Company profile

MacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeutics for the treatment of cancer in the United States.

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The company's product pipeline includes lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4 for the treatment of mCRPC and docetaxel that is in phase 2 clinical trials, as well as for the treatment of platinum-resistant ovarian cancer and clear cell gynecologic cancer which has completed phase 1 clinical trial; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload; MGC028, an antibody-drug conjugates (ADC) that targets ADAM9 and delivers a novel TOP1i-based linker-payload for the treatment of solid tumors, which is in phase 1 clinical trials; MGC030, a ADC molecule that targets an undisclosed antigen expressed across several solid tumors, which is in preclinical trials.

It is also developing T-cell engager programs. The company has collaborations with TerSera Therapeutics LLC; Incyte Corporation; and Gilead Sciences, Inc. MacroGenics, Inc. was incorporated in 2000 and is headquartered in Rockville, Maryland.

Stock analysis

MacroGenics Inc (MGNX) currently trades at $2.42, while our estimate is $2.16, 11% below the price, so the stock looks overvalued today.

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Valuation

None of our valuation models currently carries for this company, usually because of losses or heavy investment. The estimate draws on revenue and assets compared with similar companies and is less precise than a model-based fair value.

Scenario range: $1.62 (bear) to $2.71 (bull), the price of $2.42 sits inside it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.

Quality & growth

The Quality Score stands at 42/100 (below-average quality), in the Healthcare sector.

Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.

MacroGenics Inc reported revenue of $150M in FY2025 versus $75.6M in FY2021, a compound +18.6%/yr. Reported net income was −$74.6M in FY2025.

Key figures

Market cap $154M Micro · P/S ratio 0.81 · EPS (TTM) $−1.63 · Net margin −49.9% · Return on equity −226% · Return on assets (EBIT) −45.9% (5-year average) · Operating margin −42.2% · Revenue (TTM) $175M.

Competitive moat

Our AI-assisted moat analysis scores the competitive advantage at 9 out of 100 (medium confidence).

What moves the price

The share trades about 50% below its 52-week high and 82% above its 52-week low, currently below its 200-day average.

For context, the median of 10 Healthcare peers we cover trades at −7% fair-value upside, at −11%, MGNX screens richer than that median.

Fair Value

Bear $1.62 Fair Value $2.16 Bull $2.71
Price $2.42 · Downside -10.7%
Estimate. None of our valuation models currently carries for this company, usually because of losses or heavy investment. The estimate draws on revenue and assets compared with similar companies and is less precise than a model-based fair value.

Quality Score breakdown

Overall quality 42/100

It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.

Profitability 23
How much profit the company makes from its sales and capital
Quality Growth 26
Are margins and returns getting better?
Cashflow 13
Do the profits arrive as real cash?
Financial strength 49
Debt, balance sheet and risk of trouble
Investment 100
Does it invest with discipline instead of growing at any price?
Low Volatility 18
How calm the share price moves, does not count
Price momentum 33
Price momentum of the last 3 to 12 months, does not count
Near the 52-week high 66
Distance to the 52-week high, does not count
New shares 74
Buys back shares or issues new ones?

Open the full quality analysis →

Insider trades

In the last 6 months, one officer or director sold shares worth $129,086 and none bought.

  • SaleJeffrey Stuart PetersSenior VP, GC, and Secretary31,105 shares at $4.15$129,086Aug 19, 202610b5-1 plan

Plus 11 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.

Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.

Source: SEC Form 4, as of Nov 10, 2026. All filings at the SEC ↗

Revenue & earnings trend

Growth Quality ⓘGrowth is valuable only when reinvestment earns attractive returns (Aswath Damodaran): sustainable growth depends on return on capital, reinvestment and efficiency. Basis: total company revenue over the periods shown on the cards (3Y/5Y/all years), not per share, so a merger can show up as a growth jump; per-share earnings growth is in the value-creation card. 24/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Revenue growth 1 year
+0.8%
Revenue growth 3 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
−0.5%
Revenue growth 5 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+8.9%
Start year 2020 (pandemic). Over 10 years: +4.0% a year
Revenue growth 14 years ⓘMeasures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump. Per-share growth (which does include buybacks) is in the value-creation card.
+8.6%
Profit margin (trend) ⓘOperating margin then vs now, from reported annual statements. A falling margin after a boom year is the classic peak-earnings signal: the growth rate then leans on an inflated base.
−134.1% (2020) → −48.7% (2025)
What shareholders gained per year ⓘWe only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed

MGNX screens overvalued: fair value 11% below the price. Compare with Vertex Pharmaceuticals Incorporated →

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Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 849 stocks

Beats the industry median on 5/9 measures
A mixed picture versus its industry peers.
Valuation
Quality Score 42 · Above median
Fair Value upside −10.7% · Above median
Profitability
Return on assets −29.1% · Below median
Net margin (12 months) −8.3% · Below median
Operating margin (12 months) −42.2% · Bottom 25%
Growth and dividend
Revenue growth (quarter YoY) 378.0% · Top 25%

Valuation Multiplesvs Biotechnology median · lower = cheaper

P/B 2.77× · Pricier than median
P/S (12 months) 0.88× · Cheapest 25%
PEG 0.01× · Cheapest 25%

Strength profile in five axes (Snowflake)

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE (fair-value potential)19 · sector 0
FUTURE (revenue growth)100 · sector 0
PAST (return on equity)0 · sector 0
HEALTH (low debt)100 · sector 96
DIVIDEND (yield)0 · sector 20

Context: sector, industry, market

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate.

Stock Price Fair Value vs Fair Value Compare
Regeneron Pharmaceuticals, Inc REGN $916.06 $1,275 +39% vs MGNX
Samsung Biologics Co 207940 1,468,000 KRW 1,661,000 KRW +13% vs MGNX
Vertex Pharmaceuticals Incorporated VRTX $547.89 $601.80 +10% vs MGNX
Genmab A/S GMAB kr 3,581 kr 3,880 +8% vs MGNX
argenx SE ARGX $971.55 $908.40 −7% vs MGNX
CSL Limited CSL A$201.68 A$181.40 −10% vs MGNX
Moderna, Inc MRNA $250.83 $158.70 −37% vs MGNX
BeOne Medicines AG 6160 HK$252.20 HK$152.80 −39% vs MGNX
Celltrion, Inc 068270 203,000 KRW 74,945 KRW −63% vs MGNX
Royalty Pharma plc RPRX $69.45 $19.01 −73% vs MGNX

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MacroGenics Inc: fair value per Fair Value Calculator

Cite: Fair Value Calculator (2026). "MacroGenics Inc Fair Value". https://www.fairvalue-calculator.com/stock/MGNX

Frequently asked questions

Is MacroGenics Inc (MGNX) overvalued or undervalued?
As of Nov 10, 2026, our estimate of fair value is $2.16 versus a price of $2.42, about 11% lower (overvalued).
What is the fair value of MGNX?
Our estimate for MacroGenics Inc is $2.16 (as of Nov 10, 2026), built from audited fundamentals. The current price: $2.42.
What is the quality score of MGNX?
MacroGenics Inc has a Quality Score of 42/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the price target for MacroGenics Inc (MGNX)?
Our calculated price target is the estimate of $2.16 (as of Nov 10, 2026). Cautious scenario $1.62, optimistic scenario $2.71. It is an estimate from revenue and assets compared with similar companies, because none of our valuation models currently carries, not an analyst target.
What is the MacroGenics Inc stock forecast for 2026?
Our estimate puts fair value at $2.16, about 11% lower versus a price of $2.42 (overvalued). Cautious scenario $1.62, optimistic scenario $2.71. The calculation is refreshed regularly with new filings.
What is the revenue of MacroGenics Inc (MGNX)?
MacroGenics Inc reported trailing-twelve-month revenue of about $175M (latest available figure, as of Nov 10, 2026).
What is the intrinsic value of MacroGenics Inc (MGNX)?
Intrinsic value and fair value mean the same thing: what the business is worth on its numbers, independent of the share price. For MacroGenics Inc it is $2.16 per share (as of Nov 10, 2026), against a price of $2.42.
Is MacroGenics Inc stock overvalued or undervalued in 2026?
As of Nov 10, 2026, MGNX trades above its calculated fair value: price $2.42, fair value $2.16, a gap of about −11% (overvalued). The calculation is refreshed with each new quarterly report, so the verdict can change during the year.
Is fair value the same as the market price of MGNX?
No. The price is what the market pays today ($2.42); the fair value is what the company's own numbers justify ($2.16). For MacroGenics Inc the two are $0.2600 per share apart. That gap is exactly why we show both numbers side by side.
How much is MacroGenics Inc worth?
The market values MacroGenics Inc at about $154M (market capitalisation, as of Nov 10, 2026). Per share that is $2.42; our models calculate a fair value of $2.16 per share.
What do the bullish and bearish scenarios say about MGNX?
Our models span a range for MacroGenics Inc: cautious scenario $1.62, base $2.16, optimistic $2.71 per share (as of Nov 10, 2026, price $2.42). The range comes from different growth and margin assumptions, not from analyst opinions.
What is the PEG ratio of MGNX?
The PEG ratio of MacroGenics Inc is 0.01 (P/E divided by earnings growth, as of Nov 10, 2026). That is below 1, so growth is priced more cheaply than the earnings multiple alone suggests.
How solid is the balance sheet of MacroGenics Inc (MGNX)?
Balance-sheet figures for MacroGenics Inc (as of Nov 10, 2026): return on equity −225.9%. They feed the Quality Score of 42/100, which measures business quality independently of the share price.
How far is MGNX from its 52-week high?
MacroGenics Inc trades at $2.42, about 50% below its 52-week high of $4.86 and 82% above the low of $1.33 (as of Nov 10, 2026). Distance from the high says nothing about value: that is what the fair value of $2.16 is for.
Which stocks are comparable to MacroGenics Inc?
From the same area (Healthcare) we also value Vertex Pharmaceuticals Incorporated, Moderna, Inc, Regeneron Pharmaceuticals, Inc, CSL Limited, among others. Each of them has its own fair-value calculation on this site using the same models, so the comparison is like for like.
Is MacroGenics Inc stock attractive at the current price?
The data as of Nov 10, 2026: price $2.42, calculated fair value $2.16 (−11%), Quality Score 42/100. Whether that fits your horizon and risk tolerance is your call. We provide the calculation, not investment advice.
Is it still worth investing in stocks now?
The global stock market currently sits 15.1% above its aggregate fair value. MacroGenics Inc itself currently trades above fair value. An expensive market is no reason to stay out and no reason to buy everything at once: keep a broad savings plan running, buy single stocks only with money you can do without, and hold part of your money liquid while the market is high. The full picture including sectors is on is it worth investing now.
What is the share price of MacroGenics Inc (MGNX)?
The closing price on Nov 10, 2026 was $2.42. Our estimate is $2.16, about 11% lower (overvalued). We carry closing prices from our data provider, not a live tick.
What should I pay attention to with MacroGenics Inc right now?
Evidence is limited here (fewer models, shorter history), so the fair value is a rougher estimate than usual. The price sits in the upper half of our model range, so the margin of safety is thin. Read the verdict with care: some models are missing inputs, so the estimate scatters more than usual.

Key figures of MacroGenics Inc

How large is the market capitalisation of MacroGenics Inc (MGNX)?
The market capitalisation of MacroGenics Inc is $154M. The stock-market value of the whole company: share price times number of shares. It is what the market asks for the entire business today.
What is the P/S ratio of MacroGenics Inc (MGNX)?
The price-to-sales ratio of MacroGenics Inc is 0.81 (last twelve months). Price to sales: market value relative to yearly revenue. Useful when profit is thin or distorted.
What are the earnings per share of MacroGenics Inc (MGNX)?
Earnings per share at MacroGenics Inc are $−1.63. Earnings per share over the last twelve months: total profit spread across every single share.
What is the net margin of MacroGenics Inc (MGNX)?
The net margin of MacroGenics Inc is −49.9% (fiscal year 2025). How much of every unit of revenue ends up as profit. 10% means 10 cents of profit per dollar of sales.
What is the return on equity of MacroGenics Inc (MGNX)?
The return on equity (ROE) of MacroGenics Inc is −226% (last twelve months). Profit relative to shareholders' equity, how efficiently the company works with its owners' money.
What is the EBIT return on assets of MacroGenics Inc (MGNX)?
On an EBIT basis the return on assets of MacroGenics Inc is −45.9% (avg 5y). Operating profit (EBIT) relative to everything the company owns, as a multi-year average. It describes the business model rather than one good or bad year.
What is the operating margin of MacroGenics Inc (MGNX)?
The operating margin of MacroGenics Inc is −42.2% (last twelve months). Profit from the core business (before interest and taxes) relative to revenue.
How fast is revenue growing at MacroGenics Inc (MGNX)?
Revenue at MacroGenics Inc is growing +378% versus a year earlier (3y avg −0.5%). How much revenue grew versus a year earlier (YoY). The 3-year average next to it puts the single year in context.
How fast are earnings growing at MacroGenics Inc (MGNX)?
Earnings per share at MacroGenics Inc are growing −70.4% versus a year earlier. How much earnings per share grew versus a year earlier.
How much free cash flow does MacroGenics Inc (MGNX) generate?
The free cash flow of MacroGenics Inc is −$83.0M (fiscal year 2025). The cash truly left after running and investing in the business, this is what pays dividends and buybacks.
How much net debt does MacroGenics Inc (MGNX) carry?
The net debt of MacroGenics Inc is $49.5M (fiscal year 2025). Debt minus cash on hand. The note shows how many years of free cash flow could in theory pay it off.
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