AstraZeneca PLC (AZN) fair value: what the stock is really worth
As of Nov 5, 2026: fair value (intrinsic value) of AstraZeneca PLC stock £94.67, price £140, that is 32.6% below the price, quality 72 out of 100. Rating: overvalued. Calculated from audited financials with 24 of our 26 valuation models and 37 quality factors, updated daily.
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AstraZeneca PLC
AZN · LSEOur calculation puts a fair price 33% below what the stock costs today.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 6, 2026.
How to read this chart
60‑month range £72.66 – £154.39 · fair‑value band £55.97 – £128.44 · the £140.42 price screens above the £94.67 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 6, 2026.
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Company profile
AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines.
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The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Crestor, Andexxa, Onglyza, Symlin, XIGDUO XR, Atacand, Atacand HCT, Atacand Plus, Farxiga/Forxiga, Plendil, Modip, Splendil, Munobal, Flodil, Tenormin, Tenormine, Prenormine, Atenol, Zestril, Brilinta/Brilique, Komboglyze, Qtern, Wainua, Byetta, Lokelma, Seloken ZOK, Toprol-XL, Betaloc ZOK, XIGDUO, Accolate, Accoleit, Vanticon, Bricanyl Respules, Eklira Genuair/Tudorza/Bretaris, Pulmicort Turbuhaler, Symbicort Turbuhaler, Airsupra, Bricanyl Turbuhaler, Fasenra, Rhinocort, Tezspire, Bevespi Aerosphere, Daliresp/Daxas, Oxis Turbuhaler, Saphnelo, Breztri Aerosphere, Duaklir Genuair, Pulmicort Respules, and Symbicort pMDI. It also provides Beyfortus, Kavigale, Evusheld, Fluenz/FluMist, Synagis, Kanuma, Ultomiris, Koselugo, Voydeya, Soliris, Strensiq, Nexium, and other medicines.
The company offers its products for ocology, cardiovascular, renal and metabolism, respiratory & immunology, vaccines and immune, and therapies rare diseases.
It serves primary and specialty care physicians through distributors and local representative offices in the United Kingdom, the Americas, rest of Europe, Asia, Africa, and Australasia.
It has a strategic agreement with Tempus and Pathos to develop the largest multimodal foundation model in oncology; CSPC Pharmaceutical Group Limited to advance the discovery and development of novel oral candidates, with the potential to treat diseases across multiple indications; and Nucs AI Inc. to develop AI-driven Response Prediction for Therapeutic Radioconjugates.
The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.
Stock analysis
AstraZeneca PLC (AZN) currently trades at £140.42, while our model-based Fair Value estimate is £94.67, 33% below the price, so the stock looks overvalued today.
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Valuation
Bull case: the Multiples group reads highest at a median of £100.46 per share, and 0 of the 24 models we run sit above the £140.42 price.
Bear case: the Earnings-Based group reads lowest at £31.64, and 24 of the 24 models stay below the price. Data coverage for this calculation is high.
Scenario range: £55.97 (bear) to £128.44 (bull), the price of £140.42 sits above it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 72/100 (solid quality), in the Healthcare sector.
Healthy Growth: Revenue growth appears healthy and is supported by profitability and cash-flow quality.
AstraZeneca PLC reported revenue of $58.7B in FY2025 versus $37.1B in FY2021, a compound +12.2%/yr. Reported net income was $10.2B in FY2025, compounding +210.6%/yr from FY2021. FY2021 was a trough year, so the rate overstates the trend.
Key figures
Market cap £219B Mega · P/E ratio 28.1 · P/S ratio 4.90 · EPS (TTM) £4.99 · Dividend yield 1.7% · Net margin 17.4% · Return on equity 22.6% · Return on assets (EBIT) 8.3%.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 81 out of 100 (medium confidence).
What moves the price
The last reported earnings sit well below what analysts expect (earnings in transition, for example after write-downs or an earnings dip); whether the stock is cheap or expensive hinges on the expected recovery actually arriving. Read the fair value with that caveat.
The share trades about 9% below its 52-week high and 23% above its 52-week low, currently above its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at −11% fair-value upside, at −33%, AZN screens richer than that median.
Fair Value models
All 24 models by family
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Revenue & earnings trend
Growth Forecast
AZN screens overvalued: fair value 33% below the price. Compare with Eli Lilly and Company →
Recent news
- AstraZeneca (LSE:AZN) Filing Acceptance In Europe And Japan Puts Lung Cancer Combo Forward
- AstraZeneca (LSE:AZN) Posted Positive Phase III Results For Three Cancer Drugs
- AstraZeneca (LSE:AZN) Reports Positive Phase III Results In Eosinophilic Esophagitis
- AstraZeneca (LSE:AZN) Could Be 22% Undervalued On AI Partnership And Pipeline Updates
Compare AstraZeneca PLC with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Drug Manufacturers - General · 74 stocks
Valuation Multiplesvs Drug Manufacturers - General median · lower = cheaper
Strength profile in five axes (Snowflake)
VALUE 0: the price sits above our fair-value range.
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
- Dividend yield by industry
- EV/EBITDA by industry
- Piotroski F-Score screener with fair value
- Undervalued stocks: UK Stocks
- Valuation of the UK market
Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Drug Manufacturers - General stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| Bristol-Myers Squibb Company BMY | $63.13 | $75.91 | +20% | vs AZN |
| Gilead Sciences, Inc GILD | $167.57 | $191.93 | +15% | vs AZN |
| Amgen Inc AMGN | $460.28 | $507.39 | +10% | vs AZN |
| AbbVie Inc ABBV | $288.24 | $259.62 | −10% | vs AZN |
| Novartis AG NOVN | CHF 134.12 | CHF 119.58 | −11% | vs AZN |
| Merck & Co MRK | $146.94 | $129.26 | −12% | vs AZN |
| Pfizer Inc PFE | $29.88 | $24.87 | −17% | vs AZN |
| Roche Holding RO | CHF 399.00 | CHF 326.56 | −18% | vs AZN |
| Johnson & Johnson, JNJ | $272.32 | $168.85 | −38% | vs AZN |
| Eli Lilly and Company LLY | $1,365 | $749.92 | −45% | vs AZN |
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Key figures of AstraZeneca PLC
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