Jazz Pharmaceuticals PLC (JAZZ) fair value: what the stock is really worth
As of Nov 5, 2026: fair value (intrinsic value) of Jazz Pharmaceuticals PLC stock $368, price $227, upside +61.7%, quality 53 out of 100. Rating: strongly undervalued. Calculated from audited financials with 13 of our 26 valuation models and 37 quality factors, updated daily.
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Jazz Pharmaceuticals PLC
JAZZ · USThe stock costs 38% less than our calculation considers fair.
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Price vs Fair Value
White line = price, green steps = our fair value per fiscal year. As of Nov 3, 2026.
How to read this chart
60‑month range $97.78 – $261.62 · fair‑value band $178.25 – $656.64 · the $227.32 price screens below the $367.54 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). As of Nov 3, 2026.
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Company profile
Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally.
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The company offers Xywav to treat cataplexy or excessive daytime sleepiness (EDS) with narcolepsy and idiopathic hypersomnia (IH); Epidiolex for seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC); Rylaze for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma; Enrylaze to treat acute lymphoblastic leukemia and lymphoblastic lymphoma; Zepzelca for the treatment of metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy; Ziihera to treat HER2-positive biliary tract cancers; Modeyso for the treatment of diffuse midline glioma harboring an H3 K27M mutation; and Defitelio to treat severe veno-occlusive disease.
It also develops Zanidatamab in Phase 3 trial to treat HER2-positive gastroesophageal adenocarcinoma (GEA) and biliary tract cancers (BTC); Dordaviprone to treat H3 K27M-mutant diffuse glioma; and Vyxeos for the treatment of newly-diagnosed therapy-related acute myeloid leukemia.
In addition, the company is developing Zanidatamab to treat neoadjuvant and adjuvant breast cancer; Vyxeos for the treatment of High-risk MDS, newly diagnosed untreated patients with high-risk AML, and De novo intermediate or adverse risk AML stratified by genomics; and JZP3507 to treat pheochromocytoma and paraganglioma that are in Phase 2 clinical trials.
Further, it develops JZP815 to treat Raf and Ras mutant tumors; JZP898 for the IFN INDUKIN molecule in solid tumors; and JZP047 to treat absence epilepsy that are in Phase 1 clinical trials.
The company has licensing and collaboration agreements with Redx Pharma plc, Autifony Therapeutics Limited, Zymeworks Inc., Sumitomo Pharma Co., Ltd., and Werewolf Therapeutics, Inc. Jazz Pharmaceuticals plc was founded in 2003 and is headquartered in Dublin, Ireland.
Stock analysis
Jazz Pharmaceuticals PLC (JAZZ) currently trades at $227.32, while our model-based Fair Value estimate is $367.54, implying the stock looks roughly 38% undervalued today.
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Valuation
Bull case: the DCF Models group reads highest at a median of $319.07 per share, and 9 of the 13 models we run sit above the $227.32 price.
Bear case: the Earnings-Based group reads lowest at $77.79, and 4 of the 13 models stay below the price. Data coverage for this calculation is medium.
Scenario range: $178.25 (bear) to $656.64 (bull), the price of $227.32 sits inside it. Bear and bull are the same models on cautious and optimistic assumptions, a range, not a price target.
Quality & growth
The Quality Score stands at 53/100 (solid quality), in the Healthcare sector.
Mixed Growth: Revenue is growing, but margins or cash flow do not fully confirm the trend.
Jazz Pharmaceuticals PLC reported revenue of $4.3B in FY2025 versus $3.1B in FY2021, a compound +8.4%/yr. Reported net income was −$356M in FY2025.
Key figures
Market cap $15.8B Large · P/E ratio 67.3 · P/S ratio 3.03 · EPS (TTM) $3.38 · Net margin −8.3% · Return on equity 22.1% · Return on assets (EBIT) 2.7% · Operating margin 26.9%.
Competitive moat
Our AI-assisted moat analysis scores the competitive advantage at 67 out of 100 (low confidence).
What moves the price
The last reported earnings sit well below what analysts expect (earnings in transition, for example after write-downs or an earnings dip); whether the stock is cheap or expensive hinges on the expected recovery actually arriving. Read the fair value with that caveat.
The share trades about 13% below its 52-week high and 73% above its 52-week low, currently above its 200-day average.
For context, the median of 10 Healthcare peers we cover trades at 8% fair-value upside, at 62%, JAZZ screens cheaper than that median.
Fair Value models
All 13 models by family
The fair value above starts from this blend and is adjusted for dilution from new shares.
Quality Score breakdown
It rates the business: profits, how they develop, real cash, balance sheet, investing and share count.
Insider trades
In the last 6 months, 8 officers or directors sold shares worth $32.8M and none bought.
- SaleRenee D GalaPresident & CEO, Director3× since Sep 8, 2026: 5,000 shares, avg. $236.85$1.2MNov 3, 202610b5-1 plan
- SaleBruce C CozaddDirector11× since Nov 18, 2025: 149,500 shares, avg. $194.45$29.1MNov 2, 2026
- SaleNeena M PatilEVP & Chief Legal Officer4× since Feb 26, 2026: 59,192 shares, avg. $194.29$11.5MSep 10, 2026
- SaleRobert IannoneEVP, Global Head of R&D & CMO2× since Nov 17, 2025: 84,080 shares, avg. $242.77$20.4MAug 27, 202610b5-1 plan
- SaleMark Douglas SmithDirector1,157 shares at $230.55$266,746Jun 15, 202610b5-1 plan
- SaleSamantha PearceEVP, Chief Commercial Officer6,907 shares at $235.41$1.6MMay 28, 2026
- SaleRick E WinninghamDirector2× since Nov 18, 2025: 8,241 shares, avg. $201.05$1.7MMay 22, 2026
- SaleHeather Ann McSharryDirector2× since Nov 20, 2025: 5,415 shares, avg. $201.13$1.1MMay 22, 2026
- SalePatricia CarrSVP, Chief Accounting Officer4× since Nov 18, 2025: 13,636 shares, avg. $180.26$2.5MMar 9, 2026
- SaleNorbert G RiedelDirector3,415 shares at $192.00$655,680Feb 27, 2026
Plus 1 more entries from the last 12 months.
Plus 35 other filings such as grants, option exercises or tax withholding. They are not market purchases or sales.
Sales are often planned (taxes, diversification, 10b5-1 plans). Purchases with their own money are seen as the stronger sign. For information only: not part of the quality score or Fair Value.
Source: SEC Form 4, as of Nov 5, 2026. All filings at the SEC ↗
Revenue & earnings trend
Growth Forecast
Watch JAZZ, get fair value alerts →
Recent news
- What to expect from Jazz Pharmaceuticals’s (JAZZ) Q3 earnings
- Analysts Estimate Jazz Pharmaceuticals (JAZZ) to Report a Decline in Earnings: What to Look Out for
Compare Jazz Pharmaceuticals PLC with another stock
Price, fair value, quality and upside side by side.
Peer GroupⓘHow this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.Biotechnology · 566 stocks
Valuation Multiplesvs Biotechnology median · lower = cheaper
Strength profile in five axes (Snowflake)
Context: sector, industry, market
- Is the Health Care sector expensive or cheap?
- P/E, EV/EBITDA and margins by industry (reference tables)
- Return on equity by industry
- Quality Score by industry
- PEG screener for stocks with fair value
- Undervalued stocks: US Stocks
- Valuation of the USA market
Values & ESG
Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.
Similar stocks
10 more Biotechnology stocks, each showing price versus our Fair Value estimate.
| Stock | Price | Fair Value | vs Fair Value | Compare |
|---|---|---|---|---|
| Regeneron Pharmaceuticals, Inc REGN | $902.90 | $1,275 | +41% | vs JAZZ |
| Vertex Pharmaceuticals Incorporated VRTX | $542.50 | $608.47 | +12% | vs JAZZ |
| Genmab A/S GMAB | kr 3,635 | kr 4,068 | +12% | vs JAZZ |
| WuXi Biologics (Cayman) Inc 2269 | HK$48.68 | HK$53.55 | +10% | vs JAZZ |
| Samsung Biologics Co 207940 | 1,520,000 KRW | 1,644,500 KRW | +8% | vs JAZZ |
| argenx SE ARGX | $894.77 | $908.40 | +2% | vs JAZZ |
| CSL Limited CSL | A$202.04 | A$180.38 | −11% | vs JAZZ |
| BeOne Medicines AG 6160 | HK$248.60 | HK$153.56 | −38% | vs JAZZ |
| Celltrion, Inc 068270 | 215,000 KRW | 74,945 KRW | −65% | vs JAZZ |
| Royalty Pharma plc RPRX | $67.57 | $19.01 | −72% | vs JAZZ |
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Key figures of Jazz Pharmaceuticals PLC
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