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AN2 Therapeutics, Inc (ANTX) Fair Value & Analysis

Healthcare · US · Market cap $176M

AT AN2 Therapeutics, Inc logo AN2 Therapeutics, Inc ANTX · US
Price$5.93
Fair Value$1.42
Upside-76.1%
Quality51/100
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Thin margins · 0.0% net margin
negative free cash flow
Mixed vs. peers (4/8)
Narrow moat 5/100
Evidence: Low Range $0.9400 – $1.77 Share as image

Fair value as of: Jul 14, 2026

From 1 valuation models · updated 27 days ago

Fair value updated Jul 14, 2026, revised from $6.63 to $1.42 (−78.6%) since Jun 24, 2026. Share price +34.5% over the past month.

A solid business, but screening 76% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($1.77). The favourable scenario is already priced in.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.
  • Solid but not exceptional quality (51/100) and above fair value, neither a clear bargain nor a standout compounder.
  • A fairly wide model range ($0.9400 to $1.77) leaves room in how you read the outcome.
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Price vs Fair Value (4 years)

$22.29 $0.9800 Fair Value $1.42 Mar 2022 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Jul 14, 2026.

How to read this chart

52‑month range $0.9800 – $22.29 · fair‑value band $0.9400 – $1.77 · the $5.93 price screens above the $1.42 fair value. Dashed = 300-day average. As of Jul 14, 2026.

Full chart & analysis →

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Analysis

AN2 Therapeutics, Inc (ANTX) currently trades at $5.93, while our model-based Fair Value estimate is $1.42, implying the stock looks roughly 76.1% overvalued today. The Quality Score stands at 51/100 (solid quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: low).

It earns a return on equity of -44.6%. The balance sheet holds a net cash position of $19.9M. Fundamentals as of Jul 14, 2026

Our scenario range runs from $0.9400 (bear case) to $1.77 (bull case); at $5.93, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades about 14% below its 52-week high, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -43% fair-value upside, at -76%, ANTX screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
NCAV (Graham) $0.7400 $0.9900 $1.47 50
All 1 models by family
Asset-Based
NCAV (Graham) $0.7400 $0.9900 $1.47 50

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Key figures & financial health

Return on equity -44.6%
Free cash flow −$29.8M FY2025
EPS (TTM) $-1.10
Net cash $19.9M FY2025

Figures from reported company fundamentals · as of Jul 14, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 51/100

Of which business quality 55 · Market factors (momentum, volatility) 81

Profitability 0
Margins and returns on capital today
Quality Growth 45
Are margins and returns improving?
Cashflow 62
Earnings quality: real cash, not paper profit
Fin. Strength 100
Balance sheet, leverage, solvency risk
Investment 100
Disciplined investing over empire-building
Low Volatility 50
Calm price path (market factor)
Momentum 95
Price trend over the last 3–12 months (market factor)
52W Momentum 92
Distance to the 52-week high (market factor)
Net Issuance 34
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

AN2 Therapeutics, Inc., a biopharmaceutical company, focuses on discovering and developing novel small molecule therapeutics.

Full company description

AN2 Therapeutics, Inc., a biopharmaceutical company, focuses on discovering and developing novel small molecule therapeutics. The company's initial candidate includes epetraborole, which is phase 3 clinical trial as a once-daily oral treatment for patients with non-tuberculous mycobacterial lung disease, as well as studying for the treatment of acute melioidosis. It also develops AN2-502998 (AN15368), an investigational, boron-based small molecule in development for the treatment of chronic Chagas disease that is in preclinical trials; and has various research programs targeting the development of novel compounds in oncology and infectious disease based on its boron chemistry platform. It has a license agreement with Anacor Pharmaceuticals, Inc. to use, develop, manufacture, commercialize compounds and products, including epetraborole for the treatment, diagnosis, or prevention of various human diseases; and Brii Biosciences Limited to research, develop, manufacture, and commercialize compounds and products comprising epetraborole in China, Hong Kong, Taiwan, and Macau for the diagnosis, treatment, and prevention of human diseases; and GSK plc for the development of new therapies for TB. AN2 Therapeutics, Inc. was incorporated in 2017 and is headquartered in Menlo Park, California.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

AN2 Therapeutics, Inc reported revenue of $0 in FY2025 versus $0 in FY2021. Reported net income was −$35.2M in FY2025.

Revenue
FY21 $0
FY22 $0
FY23 $0
FY24 $0
FY25 $0
Net income
FY21 −$21.5M
FY22 −$41.5M
FY23 −$64.7M
FY24 −$51.3M
FY25 −$35.2M

ANTX screens 76% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "AN2 Therapeutics, Inc Fair Value". https://www.fairvalue-calculator.com/stock/ANTX

Peer Group

Biotechnology · 601 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 55 · Above median
Fair Value upside −76% · Bottom 25%
Return on assets -27% · Bottom 25%
Net margin (TTM) 0% · Above median
Operating margin (TTM) 0% · Above median
Revenue growth 0% · Above median

Valuation Multiples vs Biotechnology median · lower = cheaper

P/B 3.33× · Pricier than 75% of peers

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Jul 14, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $486.03 $278.78 -43%
Regeneron Pharmaceuticals, Inc REGN $664.45 $594.40 -11%
Samsung Biologics Co 207940 1,368,000 KRW 1,091,384 KRW -20%
Celltrion, Inc 068270 175,800 KRW 76,325 KRW -57%
WuXi Biologics (Cayman) Inc 2269 HK$39.54 HK$30.42 -23%
Innovent Biologics, Inc 1801 HK$86.70 HK$19.66 -77%
Sino Biopharmaceutical Limited 1177 HK$5.26 HK$3.36 -36%
ALTEOGEN Inc 196170 276,500 KRW 44,444 KRW -84%
RemeGen Co 688331 ¥134.02 ¥26.99 -80%
Biocon Limited BIOCON ₹440.70 ₹57.36 -87%

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Frequently asked questions

Is AN2 Therapeutics, Inc (ANTX) overvalued or undervalued?
As of Jul 14, 2026, our model estimates a fair value of $1.42 versus a price of $5.93, about −76% (overvalued).
What is the fair value of ANTX?
Our model-based fair value for AN2 Therapeutics, Inc is $1.42 (as of Jul 14, 2026), built from audited fundamentals. The current price is $5.93.
What is the quality score of ANTX?
AN2 Therapeutics, Inc has a Quality Score of 51/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the net profit margin of ANTX?
The net profit margin of AN2 Therapeutics, Inc is about 0.0%, meaning it keeps roughly 0.0% of revenue as net income. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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